Phytochemical Investigation of and Anti-Inflammatory Butenolide Derivatives.

Phytochemical investigation of the whole plant of Kunth led to the isolation and characterization of a butanolide, rosmarinosin B (), that was isolated from natural sources for the first time, a new butenolide, 5--acetyl bracteanolide A (), and a new apocarotenoid, 2-hydroxyisololiolide (), together with 25 known compounds (compounds - and -). The structures of the new compounds were elucidated by analysis of their spectroscopic data, including MS, 1D, and 2D NMR experiments, and comparison with literature data of known compounds. Furthermore, four butenolides - were synthesized as novel derivatives of bracteanolide A.

Phytochemicals from Tradescantia albiflora Kunth Extracts Reduce Serum Uric Acid Levels in Oxonate-induced Rats.

Background: Tradescantia albiflora (TA) Kunth (Commelinaceae) has been used for treating gout and hyperuricemia as folklore remedies in Taiwan. Therefore, it is worthwhile to study the effect of TA extracts on lowering uric acid activity. The hypouricemic effects of TA extracts on potassium oxonate (PO)-induced acute hyperuricemia were investigated for the first time.