Phosphoglucose isomerase gene expression as a prognostic biomarker of gastric cancer.

Objective: Tumor heterogeneity renders identification of suitable biomarkers of gastric cancer (GC) challenging. Here, we aimed to identify prognostic genes of GC using computational analysis.

Methods: We first used microarray technology to profile gene expression of GC and paired nontumor tissues from 198 patients.

The novel lncRNA p4516 acts as a prognostic biomarker promoting gastric cancer cell proliferation and metastasis.

Emerging evidence has shown that long noncoding RNAs (lncRNAs) participate in oncogenesis and tumor progression. We previously found a novel lncRNA p4516 which was closely associated with prognosis by preliminary study of lncRNA expression profile from paired tumors and nontumor tissues in 198 gastric cancer (GC) patients. However, the exact biological functions and the underlying molecular mechanisms of p4516 in gastric tumorigenesis still remain unclear.

Applying spatial analysis techniques to assess the suitability of multipurpose uses of spring water in the Jiaosi Hot Spring Region, Taiwan.

The Jiaosi Hot Spring Region is one of the most famous tourism destinations in Taiwan. The spring water is processed for various uses, including irrigation, aquaculture, swimming, bathing, foot spas, and recreational tourism. Moreover, the multipurpose uses of spring water can be dictated by the temperature of the water.