Publications by authors named "Han Li-Jie"

Article Synopsis
  • Circular RNAs (circRNAs) are important non-coding RNAs linked to various diseases, especially cancers, but their roles in cervical cancer are not well understood.
  • Recent studies identified 45 circRNAs significantly expressed in cervical cancer tissues, with hsa_circ_0018289 showing a notable increase in expression compared to normal tissues.
  • Further experiments revealed that hsa_circ_0018289 contributes to cervical cancer cell growth and spread by acting as a "sponge" for miR-497, highlighting its potential role in promoting tumor development.
View Article and Find Full Text PDF

We retrospectively investigated outcomes of haploidentical donor (HID) transplant for adults with standard-risk acute lymphoblastic leukaemia (ALL) in first complete remission (CR1) compared with human leucocyte antigen (HLA)-matched sibling donor (MSD) and HLA-matched unrelated donor (MUD) transplants. A total of 348 adult patients were enrolled, including 127 HID, 144 MSD and 77 MUD recipients. The cumulative incidence of grade II-IV acute graft-versus-host disease (aGVHD) was 39·5%, 24·0% and 40·3% for HID, MSD and MUD, respectively (P = 0·020).

View Article and Find Full Text PDF
Article Synopsis
  • Emerging evidence indicates that the long noncoding RNA PVT1 is linked to the development of cervical cancer, with its levels found to be increased in affected tissues and cell lines.
  • The study demonstrated that reducing PVT1 via siRNA led to significant decreases in cancer cell proliferation, migration, and invasion.
  • Additionally, miR-424 was shown to be downregulated in cervical cancer, and PVT1 appears to inhibit miR-424, suggesting that PVT1 functions as a competing endogenous RNA (ceRNA), highlighting a potential new target for cervical cancer therapy.
View Article and Find Full Text PDF

Objective: Patient positioning accuracy is critical in radiotherapy. To improve the patient positioning accuracy, a double lower limb auxiliary device has been developed to fix pelvis patients to treatment couch. A clinical study for comparing new device to conventional devices has been performed.

View Article and Find Full Text PDF

Systemic administration of chemotherapeutic agents can cause indiscriminate drug distribution and severe toxicity. Until now, encapsulation and targeting of drugs have typically relied on synthetic vehicles, which cannot minimize the clearance by the renal system and may also increase the risk of chemical side effects. Cell membrane capsules (CMCs) provide a generic and far more natural approach to the challenges of drug encapsulation and delivery in vivo.

View Article and Find Full Text PDF