Angiographic signs during mechanical thrombectomy as predictors of post-stroke epilepsy: a multicenter retrospective study.

Background: Post-stroke epilepsy (PSE) is a major complication of stroke. However, data about the predictors of PSE in patients with acute ischemic stroke (AIS) undergoing mechanical thrombectomy are limited.

Objective: To evaluate the relationship between intraoperative angiographic signs and PSE risk in patients with anterior circulation AIS who underwent mechanical thrombectomy.

Regulation of the valleytronic properties in single-layer NbSeCl.

The regulation of the valleytronic properties of two-dimensional materials can contribute to the in-depth study of valley physics and improve its potential for applications in valleytronic devices. Herein, we systematically investigate the electronic properties and the modulation of the valleytronic properties in single-layer NbSeCl. Our results reveal that NbSeCl is a semiconductor with a 105.

SaTDT enhanced plant tolerance to NaCl stress by modulating the levels of malic acid and citric acid in cells.

The issue of soil salinization is a global concern that significantly impairs crop productivity, quality, and distribution. Tonoplast Dicarboxylate Transporter (TDT) is a pivotal malic acid transporter localized on the vacuolar membrane, involving in maintaining intracellular pH homeostasis in plants. However, the molecular mechanisms and regulatory pathways underlying plant salt tolerance through TDT remain elusive.

Pseudohalide Anions Driven Structural Modulation in Distorted Tetrahedral Manganese(II) Hybrids Toward Tunable Green-Red Emissions.

Mn(II)-based halides have recently garnered significant interest as emerging luminescence materials for diverse photonic applications. Generally, Mn(II) hybrids with tetrahedral coordination show green emission, however, ones with octahedral coordination give red emission. Herein, we design the synthesis of tetrahedral Mn(II) pseudohalide hybrids, (RPhP)MnBrNCS (R=phenyl, pentyl or methyl; PhP=triphenylphosphine; x=1-3), achieved by gradually substituting bromides with pseudohalides (NCS).

Low-sampling and noise-robust single-pixel imaging based on the untrained attention U-Net.

The single-pixel imaging (SPI) technique illuminates the object through a series of structured light fields and detects the light intensity with a single-pixel detector (SPD). However, the detection process introduces a considerable amount of unavoidable white noise, which has a detrimental effect on the image quality and limits the applicability of SPI. In this paper, we combine the untrained attention U-Net with the SPI model to reduce noise and achieve high-quality imaging at low sampling rates.

Differences in cell subsets between sun-exposed and unexposed skin: preliminary single-cell sequencing and biological analysis from a single case.

Introduction: The composition and subsets of skin cells continuously change in a dynamic manner. However, the specific microcosmic alterations of human photoaged skin, independent of chronologic aging, remain unclear and have been infrequently analyzed. This study aimed to evaluate the biological processes and mechanisms underlying cell-subgroup alterations in skin photoaging.

Harnessing Cross-strand π-π Interlocking for Synergistic Enhancement of Immune Checkpoint Blocking and Ferroptosis.

The dynamic nature of noncovalent bonds in peptide self-assembly allows for selective accommodation of guest molecules. However, it remains unclear how to harness coassembly to reinforce the host peptides and simultaneously improve the application defects of guest molecules. This study aims to achieve supramolecular synergy between the host and guest, further expanding the functional space of the hybrid nanostructures.

Power optimization of high-power random Raman laser with a full-open cavity.

Since the concept of distributed feedback fiber random laser was put forward, random Raman fiber laser (RRFL) has made great progress in high power operation. For RRFL with a full-open cavity, the simplest cavity structure, further power scaling was restricted by the rapid increase of high-order Stokes wave. In this paper, we demonstrate that the output power of the RRFL can be further improved by optimizing the fiber length.

Influence of Host Lattice Ions on the Dynamics of Transient Multiband Upconversion in Yb-Er Codoped NaLnF and LiLnF Microcrystals (Ln: Y, Lu, Gd).

Inorganic host matrices provide a tunable luminescence environment for lanthanide ions, allowing for the modulation of upconversion luminescence (UCL) properties. AREF (A = alkali metal, RE = rare earth) have a low phonon energy and a high optical damage threshold, making them widely used as the host matrix for UCL materials. However, the impact mechanism of alkali metal ions and lanthanide lattice ions on transient UCL dynamics in AREF remains unclear.

A Ni@C nanowire-enabled photothermal membrane for highly efficient solar-driven interfacial water purification.

Ni@C nanowires were grown with about 5 nm nickel particles uniformly distributed along the one-dimensional framework. By assembling into a membrane, Ni@C exhibited 95.7% solar spectral absorption and a high water interfacial evaporation rate of 2.

Beneath the surface: DNA barcoding of shark fins in Singapore.

The global decline of shark populations, largely driven by overfishing to supply the shark fin trade, poses a significant threat to marine ecosystems. Southeast Asia, and particularly Singapore, is a key hub for the transit and trade of shark fins that contribute to the exploitation of these apex predators. Through the use of DNA barcoding techniques, this study aimed to determine what species of shark are involved in the Singapore shark fin trade.

Hybrid Eu(II)-bromide scintillators with efficient 5d-4f bandgap transition for X-ray imaging.

Luminescent metal halides are attracting growing attention as scintillators for X-ray imaging in safety inspection, medical diagnosis, etc. Here we present brand-new hybrid Eu(II)-bromide scintillators, 1D type [EtN]EuBr·MeOH and 0D type [MeN]EuBr·MeOH, with spin-allowed 5d-4f bandgap transition emission toward simplified carrier transport during scintillation process. The 1D/0D structures with edge/face -sharing [EuBr] octahedra further contribute to lowing bandgaps and enhancing quantum confinement effect, enabling efficient scintillation performance (light yield ~73100 ± 800 Ph MeV, detect limit ~18.

Asymmetrified Benzothiadiazole-Based Solid Additives Enable All-Polymer Solar Cells with Efficiency Over 19 .

Disordered polymer chain entanglements within all-polymer blends limit the formation of optimal donor-acceptor phase separation. Therefore, developing effective methods to regulate morphology evolution is crucial for achieving optimal morphological features in all-polymer organic solar cells (APSCs). In this study, two isomers, 4,5-difluorobenzo-c-1,2,5-thiadiazole (SF-1) and 5,6-difluorobenzo-c-1,2,5-thiadiazole (SF-2), were designed as solid additives based on the widely-used electron-deficient benzothiadiazole unit in nonfullerene acceptors.

Microaerobic-mediated suppression of Klebsiella pneumoniae mucoviscosity is restored by rmpD overexpression.

Aims: Hypervirulent Klebsiella pneumoniae (hvKp) causes invasive community-acquired infections in healthy individuals, and hypermucoviscosity (HMV) is the main phenotype associated with hvKp. This study investigates the impact of microaerobic environment availability on the mucoviscosity of K. pneumoniae.

Synthesis and Catalytic Performance of Bimetallic Oxide-Derived CuO-ZnO Electrocatalysts for CO Reduction.

Steering the selectivity of electrocatalysts toward the desired product is crucial in the electrochemical reduction of CO. A promising approach is the electronic modification of the catalyst's active phase. In this work, we report on the electronic modification effects on CuO-ZnO-derived electrocatalysts synthesized via hydrothermal synthesis.

NKILA is a novel suppressor of local recurrence in women breast malignant phyllodes tumor patients via inhibition of the NF-κB pathway.

The aim of the present study was to explore the functional mechanism of NF-Kappa B-interacting Long non-protein coding RNA (NKILA) in breast malignant phyllodes tumors (BMPTs). The expression and functional role of NKILA were investigated by performing qRT‒PCR, Transwell assays, and CCK‒8 assays in primary BMPT cells. A Kaplan‒Meier curve was used to assess overall survival (OS) and local recurrence-free survival (LRFS).

Inulin-gel-based oral immunotherapy remodels the small intestinal microbiome and suppresses food allergy.

Despite the potential of oral immunotherapy against food allergy, adverse reactions and loss of desensitization hinder its clinical uptake. Dysbiosis of the gut microbiota is implicated in the increasing prevalence of food allergy, which will need to be regulated to enable for an effective oral immunotherapy against food allergy. Here we report an inulin gel formulated with an allergen that normalizes the dysregulated ileal microbiota and metabolites in allergic mice, establishes allergen-specific oral tolerance and achieves robust oral immunotherapy efficacy with sustained unresponsiveness in food allergy models.

Polymerization-Induced Hierarchical Hybrid Particles from Siloxane Emulsification Endowing Polyurethane Composite Coating with Superhydrophobicity, Thermal Insulation, and Fluorescence.

Hierarchically structural particles (HSPs) are highly regarded as favorable nanomaterials for superhydrophobic coating due to their special multiscale structure and surface physicochemical properties. However, most of the superhydrophobic coatings constructed from HSPs are monofunctional, constraining their broader applications. Moreover, traditional methods for constructing HSPs mostly rely on complicated chemical routes and template removal.

Neoadjuvant camrelizumab plus apatinib for locally advanced microsatellite instability-high or mismatch repair-deficient colorectal cancer (NEOCAP): a single-arm, open-label, phase 2 study.

Background: PD-1 blockade is highly efficacious for mismatch repair-deficient colorectal cancer in both metastatic and neoadjuvant settings. We aimed to explore the activity and safety of neoadjuvant therapy with PD-1 blockade plus an angiogenesis inhibitor and the feasibility of organ preservation in patients with locally advanced mismatch repair-deficient colorectal cancer.

Methods: We initiated a single-arm, open-label, phase 2 trial (NEOCAP) at Sun Yat-sen University Cancer Center and the Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China.