Decoding the role of in enhancing osmotic stress tolerance in rice through ABA-dependent pathways and ROS scavenging.

Plant Class III peroxidases have diverse roles in controlling root hair growth, anther development, and abiotic and biotic stress responses. However, their abiotic stress response mechanism in rice remains elusive. Here, we identified a peroxidase precursor gene, , and investigated its role in enhancing osmotic stress tolerance in rice.

Coupling phylogenetic relatedness and distribution patterns provides insights into sandburs invasion risk assessment.

Invasive sandburs (Cenchrus spp.), tropical and subtropical plants, are preferred in grasslands and agricultural ecosystems worldwide, causing significant crop production losses and reducing native biodiversity. Integrating phylogenetic relatedness and potentially suitable habitats (PSHs) to identify areas at risk of invasion is critical for prioritizing management efforts and supporting decisions on early warning and surveillance for sandbur invasions.

Effect of corneal cross-linking on biomechanical properties of swollen rabbit corneas.

Corneal cross-linking (CXL) is an effective method to prevent the progression of keratoconus. CXL combined with hypotonic riboflavin solution is a modified treatment for thin corneas, which are deemed to be below the safe thickness threshold. In this study, rabbit corneas were subjected to different hydration levels using different osmolarity of riboflavin dextran solutions before CXL.

Concurrent Spin Squeezing and Light Squeezing in an Atomic Ensemble.

Squeezed spin states and squeezed light are both key resources for quantum metrology and quantum information science, but have been separately investigated in experiments so far. Simultaneous generation of these two types of quantum states in one experiment setup is intriguing but remains a challenging goal. Here, we propose a novel protocol based on judiciously engineered symmetric atom-light interaction, and report proof-of-principle experimental results of concurrent spin squeezing of 0.

Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration.

In biological systems, nanobubbles (NBs) effectively enhance hydrogen molecule retention and scavenging reactive oxygen species (ROS), but the underlying mechanisms remain elusive. To investigate this, we prepared hydrogen NB water samples with consistent dissolved hydrogen levels but varying NB densities to explore their physicochemical properties and effects on green algae (Chlorella vulgaris) under oxidative stress induced by copper ions (Cu) and cadmium ions (Cd). The results indicated a strong correlation between the hydrogen NB number density and the 25 % inhibitory concentration of Cu over 24 h, with ROS removal efficiency increased with the NB number density.

In Situ Crystallized Ceria-Vesicle Nanohybrid Therapeutic for Effective Treatment of Inflammatory Intraocular Disease.

Posterior uveitis is a leading cause of vision impairment and blindness globally due to its detrimental effects on the choroid and retina. The condition is worsened by oxidative stress, which heightens inflammation and perpetuates a cycle of damage that current treatments only temporarily relieve. To address this, a novel treatment involving the in situ crystallization of ultrasmall cerium oxide nanoparticles (≈3 nm) on mesenchymal stem cell (MSC) extracellular vesicles (EVs) for the management of primed mycobacterial uveitis (PMU) is developed.

Realizing Exceptional Points by Floquet Dissipative Couplings in Thermal Atoms.

Exceptional degeneracies and generically complex spectra of non-Hermitian systems are at the heart of numerous phenomena absent in the Hermitian realm. Recently, it was suggested that Floquet dissipative coupling in the space-time domain may provide a novel mechanism to drive intriguing spectral topology with no static analogs, though its experimental investigation in quantum systems remains elusive. We demonstrate such Floquet dissipative coupling in an ensemble of thermal atoms interacting with two spatially separated optical beams, and observe an anomalous anti-parity-time symmetry phase transition at an exception point far from the phase-transition threshold of the static counterpart.

[Retracted] Long non‑coding RNA Igf2as controls hepatocellular carcinoma progression through the ERK/MAPK signaling pathway.

[This retracts the article DOI: 10.3892/ol.2017.

Immunomagnetic particles exhibiting programmable hierarchical flower-like nanostructures for enhanced separation of tumor cells.

Immunomagnetic particles are extensively used for the separation of biological molecules and particles, and have exhibited great potential in many fields including biosensors, disease diagnosis and biomedical engineering. However, most immunomagnetic particles exhibit a smooth surface, resulting in a limited separation efficiency for biological particles featuring enormous surface nanostructures, such as tumor cells. Here we report flower-like immunomagnetic particles (FIMPs) prepared by streptavidin (SA)-assisted biomineralization and one-step antibody modification, and demonstrate their superior capability for highly efficient and selective separation of circulating tumor cells (CTCs).

Deep brain stimulation and lag synchronization in a memristive two-neuron network.

In the pursuit of potential treatments for neurological disorders and the alleviation of patient suffering, deep brain stimulation (DBS) has been utilized to intervene or investigate pathological neural activities. To explore the exact mechanism of how DBS works, a memristive two-neuron network considering DBS is newly proposed in this work. This network is implemented by coupling two-dimensional Morris-Lecar neuron models and using a memristor synaptic synapse to mimic synaptic plasticity.

The beetle's structural protein CPCFC making elytra tough and rigid.

The insect cuticle, which serves as both a protective barrier and an efficient lever system for locomotion, is an extracellular matrix primarily composed of chitin and protein. The cuticle protein CPCFC characterized by a "CFC" motif containing 2 Cys split by the insertion of 5 residues is distributed across most insect species and specifically localized in the hard part of the cuticle. However, their physiological function is not fully understood.

Effect of hot-air drying on drying characteristics and quality of tiger nut.

Background: The delayed drying of newly harvested tiger nuts can lead to mold and rancidity. Timely drying is therefore important. However, few studies have analyzed the impact of hot-air drying on the quality of tiger-nut oil and starch, making it essential to establish optimal drying conditions.

Diabetes Distress and Associated Factors Among Chinese Americans with Type 2 Diabetes in New York City.

Purpose: The purpose of this study is to describe diabetes distress and related factors among Chinese Americans with type 2 diabetes in New York City (NYC).

Methods: We conducted a secondary data analysis of the baseline data from three research studies conducted among community-dwelling Chinese American adults with type 2 diabetes. Diabetes Distress Scale (DDS) was used to measure sources of diabetes distress including emotional-, regimen-, interpersonal-, and physician-related distress.

Vigor King mitigates spermatogenic disorders caused by environmental estrogen zearalenone exposure.

Zearalenone (ZEN) has been shown to cause reproductive damage by inducing oxidative stress. Astaxanthin and L-carnitine are widely used to alleviate oxidative stress and promote sperm maturation. However, it remains uncertain whether they are effective in mitigating spermatogenesis disorders induced by ZEN.

Site-specific tethering nanobodies on recombinant adeno-associated virus vectors for retargeted gene therapy.

Recombinant adeno-associated viruses (rAAVs) have been extensively studied for decades as carriers for delivering therapeutic genes. However, designing rAAV vectors with selective tropism for specific cell types and tissues has remained challenging. Here, we introduce a strategy for redirecting rAAV by attaching nanobodies with desired tropism at specific sites, effectively replacing the original tropism.

Formate-tetrahydrofolate ligase: supplying the cytosolic one-carbon network in roots with one-carbon units originating from glycolate.

The metabolism of tetrahydrofolate (HPteGlu)-bound one-carbon (C) units (C metabolism) is multifaceted and required for plant growth, but it is unclear what of many possible synthesis pathways provide C units in specific organelles and tissues. One possible source of C units is via formate-tetrahydrofolate ligase, which catalyzes the reversible ATP-driven production of 10-formyltetrahydrofolate (10-formyl-HPteGlu) from formate and tetrahydrofolate (HPteGlu). Here, we report biochemical and functional characterization of the enzyme from Arabidopsis thaliana (AtFTHFL).

Characterizing Mental Health Status and Service Utilization in Chinese Americans With Type 2 Diabetes in New York City: Cross-Sectional Study.

Background: Emerging evidence indicates that individuals with type 2 diabetes (T2D) are more prone to mental health issues than the general population; however, there is a significant lack of data concerning the mental health burden in Chinese Americans with T2D.

Objective: The aim of this study was to explore the comorbid mental health status, health-seeking behaviors, and mental service utilization among Chinese Americans with T2D.

Methods: A cross-sectional telephone survey was performed among 74 Chinese Americans with T2D in New York City.

Biomechanical and histological changes associated with riboflavin ultraviolet-A-induced CXL with different irradiances in young human corneal stroma.

Keratoconus (KC) is a degenerative condition affecting the cornea, characterized by progressive thinning and bulging, which can ultimately result in serious visual impairment. The onset and progression of KC are closely tied to the gradual weakening of the cornea's biomechanical properties. KC progression can be prevented with corneal cross-linking (CXL), but this treatment has shortcomings, and evaluating its tissue stiffening effect is important for determining its efficacy.

CKIP-1-Loaded Cartilage-Affinitive Nanoliposomes Reverse Osteoarthritis by Restoring Chondrocyte Homeostasis.

Osteoarthritis (OA) is a chronic joint disease characterized by cartilage imbalance and disruption of cartilage extracellular matrix secretion. Identifying key genes that regulate cartilage differentiation and developing effective therapeutic strategies to restore their expression is crucial. In a previous study, we observed a significant correlation between the expression of the gene encoding casein kinase-2 interacting protein-1 (CKIP-1) in the cartilage of OA patients and OA severity scores, suggesting its potential involvement in OA development.

Orthodontic maxillary molar movement-induced zygomatic pillar remodeling and its consequences on occlusal characteristics and stress distribution.

Objective: We aimed to evaluate changes in the zygomatic pillar during orthodontic treatment involving premolar extraction, analyze the effects of maxillary first molar movement on zygomatic pillar remodeling, and examine occlusal characteristics and stress distribution after remodeling.

Methods: Twenty-five patients who underwent premolar extraction were included in the study. The zygomatic pillar measurement range was defined, and cross-sectional areas, surface landmark coordinates, alveolar and cortical bone thicknesses, and density changes were assessed using Mimics software based on the cone-beam computed tomography scans taken before (T0) and after the treatment (T1).

Investigating oral microbiome profiles in patients with cleft lip and palate compared with the healthy control.

Background: Patients with cleft lip and palate (CLP) have an oronasal communication differed from the closed state in healthy individuals, leading to a unique oral microbiome. This study aimed to determine if variances in the oral microbiota persist among CLP patients who have received treatments for the closure of these fistulas compared to the microbiota of healthy individuals.

Methods: Saliva samples were collected from a cohort comprising 28 CLP patients (CLP group) and 30 healthy controls (HC group).