- Gastrointestinal parasite infections, particularly Ascaris lumbricoides, are a major public health issue in humid regions, affecting around 1.5 billion people globally; they can lead to various health disorders.
- A study involving 100 infected children and 50 healthy controls examined the immune response to A. lumbricoides, focusing on the levels of interleukins IL-4, IL-5, and TNF-α which are crucial for combating these infections.
- Results indicated significant differences in TNF-α and IL-5 levels between different age groups and infection severity, suggesting that age and infection status affect the cytokine response, while IL-4 levels showed no significant variance between age