Publications by authors named "Hamsa Reddy"
Background: Urinary tract infections (UTIs) are the second most common cause of graft dysfunction, accounting for significant morbidity, and are associated with poor graft and patient survival. This study aimed to assess the association between post-renal transplant UTI and graft outcomes.
Methods: We examined the effect of UTIs on graft outcomes in patients who underwent renal transplantation surgery between January 2010 and December 2022.
Article Synopsis
- * Children with CKD stages 2-4 received cholecalciferol either daily, weekly, or monthly, and significant increases in certain bone health markers were observed, especially in the weekly dosing group.
- * Results indicated that while all dosing regimens led to similar improvements in bone biomarkers, the weekly regimen had a notable advantage in one specific marker, providing flexibility in treatment options to enhance adherence.
Article Synopsis
- The study addresses the high prevalence of vitamin D deficiency in children with chronic kidney disease (CKD) and aims to create a population pharmacokinetic (PK) model for colecalciferol to improve dosing recommendations.
- Data from 83 children with CKD were analyzed using a complex modeling approach to understand how factors like kidney disease type and serum creatinine affect vitamin D levels.
- The findings suggest that using a weight-based dosing strategy for colecalciferol can optimize vitamin D levels and reduce the risk of overdose in this population.
Background: The optimal treatment regimen for correcting 25-hydroxyvitamin D (25OHD) deficiency in children with chronic kidney disease (CKD) is not known. We compared cholecalciferol dosing regimens for achieving and maintaining 25OHD concentrations ≥30 ng/mL in children with CKD stages 2-4.
Methods: An open-label, multicentre randomized controlled trial randomized children with 25OHD concentrations <30 ng/mL in 1:1:1 to oral cholecalciferol 3000 IU daily, 25 000 IU weekly or 100 000 IU monthly for 3 months (maximum three intensive courses).
Background: Peritoneal dialysis (PD) is the preferred modality of renal replacement therapy in children with end-stage renal disease (ESRD). In developing countries, the challenges of initiating and sustaining chronic peritoneal dialysis (CPD) are many and are not well-described in the literature.
Methods: This was a retrospective study of children aged 0-18 years on manual PD.
Only few reports of failure of intradermal postexposure prophylaxis for rabies following cat scratch exist in the published literature. We are reporting such a case in a 15-year-old girl. The child had category III cat scratch on her face.
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