Publications by authors named "Hamoud Alotaibi"
Article Synopsis
- Indocyanine green (ICG) J-aggregates (IJA) show enhanced imaging and heating properties compared to monomeric ICG but have stability issues in biological environments.
- Researchers studied how different lipid compositions in liposomes affect IJA stability and performance, finding that high cholesterol and PEG-lipid content, along with low charged lipids, contributes to better performance.
- The IJA-liposomes demonstrated high biocompatibility and efficient photothermal effects in cancer models, and they cleared the body safely, with less liver accumulation compared to monomeric ICG, indicating their potential as alternatives for imaging and cancer therapy.
Indocyanine green is an FDA-approved fluorescent imaging dye used for determining cardiac output, hepatic function, liver blood flow, and retinal perfusion. It has been investigated preclinically in photoacoustic imaging and photothermal therapy (PTT); however, ICG photodegradation limits its biomedical applications. An aggregated form of ICG, known as J-aggregate (IJA), exhibits superior photoacoustic signals and thermal stability than the monomeric ICG.
View Article and Find Full Text PDFUnlabelled: : In asthma, the preventive measures taken by patients play an important role in improving life span and quality of life. This can be done more efficiently by community pharmacist by providing patient counseling and improving knowledge of patient about disease, risk factors, medication management and preventive measures to control asthma. : The objective of the study was to evaluate the contribution of community pharmacists in improvement of life span and quality of life of asthma patients.
View Article and Find Full Text PDFBackground: Community pharmacies are widely distributed and developments in this sector will greatly improve pharmaceutical health care delivery.
Objectives: To provide consumer's perceptions towards the contribution of community pharmacists in the dispensing process.
Method: The study was performed from mid-October to mid-November 2013 in Dawadmi, KSA.