Further course of mental health and use of alcohol and tranquilizers after cessation or persistence of cannabis use in young adulthood: a longitudinal study.

The main question addressed in this study is how cessation or persistence of cannabis use is related to use of legal drugs and mental health problems. In a longitudinal study a representative sample of young people in Norway, age 17-20 years (n = 1997), participated in a postal survey in 1985 and was followed up again in 1987 and 1989. The results showed a decrease in alcohol consumption among men both among those who ceased to use cannabis and those who continued their use, whereas among women who continued cannabis use the alcohol consumption increased.

Purification and characterization of an inducible L-lysine: 2-oxoglutarate 6-aminotransferase from Candida utilis.

L-Lysine:2-oxoglutarate 6-aminotransferase (EC 2.1.6.

Enzymatic production of alpha-aminoadipate-delta-semialdehyde and related compounds by lysine epsilon-dehydrogenase from Candida albicans.

L-Lysine epsilon-dehydrogenase [L-lysine:NADP+ oxidoreductase (epsilon-deaminating), EC 1.4.1.

Users and nonusers within a high risk milieu of cannabis use. A general population study.

A postal survey was carried out among a representative sample of nearly 2,000 young people in Norway (17-20 years old) in 1985, and followed up once again 2 years later. The sample was divided, according to the degree of exposure to cannabis in the peer milieu, into three groups: low, moderate, and high risk milieu. The differences between noncannabis users in high and in low risk milieux were the same as had been found in previous studies comparing users and nonusers of cannabis.

Occurrence of a novel yeast enzyme, L-lysine epsilon-dehydrogenase, which catalyses the first step of lysine catabolism in Candida albicans.

The yeast Candida albicans is able to utilize L-lysine as the sole nitrogen and carbon source accompanied by intracellular accumulation of alpha-aminoadipate-delta-semialdehyde. A novel yeast amino acid dehydrogenase catalysing the oxidative deamination of the epsilon-group of L-lysine was found in this yeast. The enzyme, L-lysine epsilon-dehydrogenase, is strongly induced in cells grown on L-lysine as the sole nitrogen source.

Initiation, continuation or discontinuation of cannabis use in the general population.

A nationally representative sample (n = 1997) of young people (17-20 years of age) was examined twice with an interval of two years using postal questionnaires supplemented by telephone interviews of non-responders. Sixty-eight per cent of the original sample participated in both surveys. Factors found to increase the probability of having ever used cannabis were sex, place of residence, divorced parents, earlier problems with education and employment, and mental and somatic health problems.

Use of alcohol and drugs in the transitional phase from adolescence to young adulthood.

The results are based on a prospective longitudinal national survey of 2000 young adults, 19-22 years old, who participated in a postal survey in 1985 and 1987; 68 per cent answered both questionnaires. This paper is mainly based on the cross-sectional analysis of the data from 1987. The transitional period from adolescence to young adulthood had a significant impact on both alcohol consumption and use of cannabis.

Occurrence of the general control of amino acid biosynthesis in yeasts.

The response of three amino acid biosynthetic enzymes, threonine dehydratase, tyrosine aminotransferase and saccharopine dehydrogenase, to conditions of histidine, tryptophan or lysine limitation was investigated in 15 yeast species. The activities of all these enzymes increased about two- to fourfold as a result of action of the general control of amino acid biosynthesis in Brettanomyces anomalus, Candida maltosa, Hansenula polymorpha, Rhodosporidium toruloides, Saccharomyces cerevisiae and Yarrowia lipolytica. No evidence for the existence of the general control was found in Candida brumptii, Candida utilis, Hansenula anomala, Hansenula henricii, Kluyveromyces marxianus, Pichia guilliermondii, Saccharomycopsis capsularis, Trichosporon adeninovorans and Trigonopsis variabilis.

The increase in alcohol consumption among women: a phenomenon related to accessibility or stress? A general population study.

This population survey of Norwegian women (N = 3997) and their husbands explore the relative importance of accessibility and stress variables in explaining the level of women's alcohol consumption. Among the accessibility-variables, population density and husbands' alcohol consumption have a significant impact on the women's consumption. Employment among women is not significantly related to their alcohol use when controlling for the husbands' consumption.

Psychopathology, parent relations, and careers in vocational training: a prospective study.

Twenty substance-abusing male clients, representative of the clients participating in a vocational training program in Oslo, were followed prospectively during 2-3 years. Forty-two percent of the nonpsychotic clients completed the training program as opposed to 25% in the psychotic/near psychotic group. All dropouts reported a feeling of being rejected by their fathers as opposed to 28% of the clients who completed the program (p less than .

Brief psychotherapy for hyepremesis gravidarum.

Brief, nonintensive psychotherapy produced a rapid, complete and permanent cure of hyperemesis gravidarum (pernicious vomiting in pregnancy). The treatment involved identification and amelioration of some common, superficial sources of anxiety during pregnancy. This method can be utilized by a nonpsychiatric physician and is recommended as quick, effective, safe and inexpensive.