Differential Psychological Treatment Effects in Patients With Late-Life Depression and a History of Childhood Maltreatment.

Objective: This is the first interventional study to assess the impact of childhood maltreatment (CM) on psychological treatment outcomes in patients with late-life depression (LLD).

Methods: This is a secondary analysis of a multicenter, randomized controlled trial with 251 participants aged ≥60 years with moderate to severe depression. Participants were randomly assigned to cognitive behavioral therapy for late life depression (LLD-CBT) or to a supportive intervention (SUI).

From Calcium to Cadmium: Testing the Pairing Functional through Charge Radii Measurements of ^{100-130}Cd.

Differences in mean-square nuclear charge radii of ^{100-130}Cd are extracted from high-resolution collinear laser spectroscopy of the 5s ^{2}S_{1/2}→5p ^{2}P_{3/2} transition of the ion and from the 5s5p ^{3}P_{2}→5s6s ^{3}S_{1} transition in atomic Cd. The radii show a smooth parabolic behavior on top of a linear trend and a regular odd-even staggering across the almost complete sdgh shell. They serve as a first test for a recently established new Fayans functional and show a remarkably good agreement in the trend as well as in the total nuclear charge radius.

High precision hyperfine measurements in Bismuth challenge bound-state strong-field QED.

Electrons bound in highly charged heavy ions such as hydrogen-like bismuth Bi experience electromagnetic fields that are a million times stronger than in light atoms. Measuring the wavelength of light emitted and absorbed by these ions is therefore a sensitive testing ground for quantum electrodynamical (QED) effects and especially the electron-nucleus interaction under such extreme conditions. However, insufficient knowledge of the nuclear structure has prevented a rigorous test of strong-field QED.

Simple Nuclear Structure in (111-129)Cd from Atomic Isomer Shifts.

Isomer shifts have been determined in ^{111-129}Cd by high-resolution laser spectroscopy at CERN-ISOLDE. The corresponding mean square charge-radii changes, from the 1/2^{+} and the 3/2^{+} ground states to the 11/2^{-} isomers, have been found to follow a distinct parabolic dependence as a function of the atomic mass number. Since the isomers have been previously associated with simplicity due to the linear mass dependence of their quadrupole moments, the regularity of the isomer shifts suggests a higher order of symmetry affecting the ground states in addition.

Precision Test of Many-Body QED in the Be+ 2p Fine Structure Doublet Using Short-Lived Isotopes.

Absolute transition frequencies of the 2s 2S{1/2}→2p2P{1/2,3/2} transitions in Be^{+} were measured for the isotopes ^{7,9-12}Be. The fine structure splitting of the 2p state and its isotope dependence are extracted and compared to results of ab initio calculations using explicitly correlated basis functions, including relativistic and quantum electrodynamics effects at the order of mα(6) and mα(7) ⁢ln α. Accuracy has been improved in both the theory and experiment by 2 orders of magnitude, and good agreement is observed.

Spins, electromagnetic moments, and isomers of (107-129)Cd.

The neutron-rich isotopes of cadmium up to the N=82 shell closure have been investigated by high-resolution laser spectroscopy. Deep-uv excitation at 214.5 nm and radioactive-beam bunching provided the required experimental sensitivity.

Nuclear charge radius of 12Be.

The nuclear charge radius of (12)Be was precisely determined using the technique of collinear laser spectroscopy on the 2s(1/2)→2p(1/2,3/2) transition in the Be(+) ion. The mean square charge radius increases from (10)Be to (12)Be by δ(10,12)=0.69(5) fm(2) compared to δ(10,11)=0.

Vicia villosa agglutinin separates freshly isolated Peyer's Patch T cells into interleukin 5- or interleukin 2-producing subsets.

Murine L3T4 T cells freshly isolated from Peyer's Patch were fractionated based on differential adherence to Vicia villosa agglutinin (VVA). VVA adherent cells secreted IL-5, but not IL-2, after stimulation with Con A and IL-1. In striking contrast, VVA nonadherent PP L3T4 T cells secreted IL-2, but not IL-5, under the same conditions.

[Effect of tricuspid annuloplasty in mitral/aortic valve replacement on the clinical aspects and global function of the right heart chamber].

The clinical improvement after mitral or aortic valve surgery is primarily due to the correction of the aortic/mitral valve function and the subsequent decrease of pulmonary artery pressure. The hemodynamic effect of an additional tricuspid annuloplasty, however, is still unclear. To assess the influence of a tricuspid annuloplasty using DeVega- or Carpentier-technique on the clinical outcome, hemodynamics, and right ventricular function in patients with moderate to severe tricuspid insufficiency, 38 patients were studied pre- and 11 +/- 4 months postoperatively.

High-performance liquid chromatographic measurement of selected blood citric acid cycle intermediates.

We describe a high-performance liquid chromatographic (HPLC) method for analysis of the intermediates of the citric acid cycle. Using two Aminex HPX-87H columns in series at 36 degrees C, the early eluting compounds cis-aconitate, oxaloacetate, alpha-ketoglutarate and citrate-isocitrate can be resolved. Acetonitrile is used for extraction of citric acid cycle intermediates from blood as interfering ultraviolet absorbing peaks are present with perchloric acid or trichloroacetic acid extraction.