Publications by authors named "Hammami-Ghorbel Houda"
Background: Mycosis fungoides (MF) usually has an indolent course. However, some patients develop more aggressive disease and few prognostic parameters have been identified. Isolated cases of pustular MF (pMF) suggest an unfavourable prognosis.
View Article and Find Full Text PDFResearch in normal tissue radiobiology is in continuous progress to assess cellular response following ionizing radiation exposure especially linked to carcinogenesis risk. This was observed among patients with a history of radiotherapy of the scalp for ringworm who developed basal cell carcinoma (BCC). However, the involved mechanisms remain largely undefined.
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- Erythrokeratodermia variabilis (EKV) is a rare skin disorder linked to mutations in the GJB3 and GJB4 genes but can also occur due to other genetic mutations as seen in a consanguineous Tunisian family.
- Whole-exome sequencing identified a new homozygous mutation in the NIPAL4 gene in two sisters, suggesting it plays a critical role in this specific EKV phenotype.
- The younger sister displayed signs of Autosomal Recessive Congenital Ichthyosis, highlighting the variability of symptoms in EKV and reinforcing the importance of studying the NIPAL4 gene's impact on skin barrier function.
Buschke-Lowenstein tumor (BLT) is a large exophytic lesion of the anogenital region with a clinically malignant aspect but a benign histology. Because of its low incidence, this pathology is exceptional in childhood. Surgical excision is the main therapeutic approach.
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