Biotissue Curriculum Translates to Performance in the Operating Room for Gastrojejunostomy and Hepaticojejunostomy in Robotic Pancreaticoduodenectomy.

Objective: Robotic simulation training curricula aim to aid surgeons in attaining robotic operating room proficiency, but the crossover success remains to be examined.

Design: A retrospective cohort study grading robotic biotissue training models and intraoperative anastomotic videos. The curriculum included deliberate practice of inanimate drills of a hepaticojejunostomy (HJ) and gastrojejunostomy (GJ).

Correction: DDX43 mRNA expression and protein levels in relation to clinicopathological profile of breast cancer.

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Knockdown Induces Obesity and AHO Features in Early Zebrafish Larvae.

(Guanine Nucleotide-Binding Protein, Alpha Stimulating) is a complex gene that encodes the alpha subunit of the stimulatory G protein (Gα), critical for signaling through various G protein-coupled receptors. Inactivating genetic and epigenetic changes in , resulting in Gα deficiency, cause different variants of pseudohypoparathyroidism, which may manifest features of Albright hereditary osteodystrophy (AHO, a syndrome characterized by early-onset obesity and other developmental defects). Recent findings have linked Gα deficiency with isolated, severe, early-onset obesity, suggesting it as a potential, underrecognized cause of monogenic, non-syndromic obesity.

Ultrasonographic characterization of tendons and ligaments of palmar/plantar aspect of the cannon region in Egyptian donkeys.

Background: There is a scarcity of data regarding the ultrasonographic characterization of tendons and ligaments in the distal limbs of donkeys.

Aims: To determine ultrasonographic characteristics of normal tendons and ligaments at the palmar/plantar aspect of the cannon region in Egyptian donkeys.

Methods: B-mode ultrasonography was conducted for the proposed tendons and ligaments in 12 clinically normal donkeys.

Suppression of (Lepidoptera: Pyralidae) development by phytosanitary irradiation doses and their impacts on physiochemical and microbiological quality of dates.

is a serious insect pest of stored figs and dates. The irradiation sensitivity of different development stages of and large-scale testing of the proposed irradiation quarantine doses (50-500 Gy), were investigated. The impact of a PI dose of 400 Gy on the physiochemical and microbiological quality of dry dates (Bartamoda cv.

Nanohexagonal iron barium titanate nanoparticles surface-modified NiFeO composite screen-printed electrode for enzymatic glucose monitoring.

A nanocomposite of iron barium titanate/NiFeO (FBT/NF) was synthesized using sol-gel techniques to form organized hexagonal structures. The effects of NiFeO nanostructures on FBT's phase purity, morphology, and dielectric properties were systematically explored and intensively discussed. TEM imaging confirmed the hexagonal structure, and electrical measurements revealed that para-electric NF influenced the conductivity and impedance of ferroelectric FBT, with a shift in Curie temperature to lower values.

The inflammation and oxidative status of rat lung tissue following smoke/vapor exposure via E-cigarette, cigarette, and waterpipe.

Background: Tobacco smoking is a major worldwide health issue that contributes to millions of deaths annually. Electronic cigarettes (E-cigarettes) are also harmful. Smoke/vapor from E-cigarettes and tobacco products consists of free radicals and other toxic substances.

The association between health literacy and quality of life of patients with type 2 diabetes mellitus: A cross-sectional study.

Background: Health literacy-driven interventions in patients with type 2 diabetes have been found to play an important role in achieving glycemic control and enhancing diabetic self-management outcomes. The present study aimed to examine the role of health literacy as a predictor of quality of life among diabetic patients in Jordan.

Methods: This cross-sectional study enrolled 400 Type 2 diabetic patients visiting the endocrinology department at the outpatient clinic at Al Basheer Hospital in Amman, Jordan.

Efficacy and safety of coronary sinus reducer for refractory angina: a systematic review and meta-analysis of randomized controlled trials.

Refractory angina affects patients' quality of life around the world. Coronary sinus reducer (CSR) is a new therapeutic approach that has been investigated in recent years. We aimed to investigate the efficacy and safety of CSR for refractory angina.

Novel microfluidic development of pH-responsive hybrid liposomes: In vitro and in vivo assessment for enhanced wound Healing.

Wound healing is a complex biological process crucial for tissue repair, especially in chronic wounds where healing is impaired. Liposomes have emerged as promising vehicles for delivering therapeutics to facilitate wound repair. Liposomes have been explored as effective carriers for therapeutic agents.

Evaluating the Effects of BSA-Coated Gold Nanorods on Cell Migration Potential and Inflammatory Mediators in Human Dermal Fibroblasts.

Albumin-coated gold nanoparticles display potential biomedical applications, including cancer research, infection treatment, and wound healing; however, elucidating their interaction with normal cells remains an area with limited exploration. In this study, gold nanorods (GNR) were prepared and coated with bovine serum albumin (BSA) to produce GNR-BSA. The functionalized nanoparticles were characterized based on their optical absorption spectra, morphology, surface charge, and quantity of attached protein.

Immersive Technologies in Healthcare: An In-Depth Exploration of Virtual Reality and Augmented Reality in Enhancing Patient Care, Medical Education, and Training Paradigms.

Background: Virtual reality (VR) and augmented reality (AR) are rapidly gaining traction in healthcare, offering transformative opportunities for patient care, medical education, and therapeutic interventions. Despite their potential, challenges remain regarding the implementation and integration of these technologies into existing healthcare practices.

Objective: This review aims to explore the current applications of VR and AR in healthcare, particularly focusing on their roles in enhancing patient care and medical training, as well as identifying research gaps that hinder their widespread adoption.

GC-MS, Antibacterial and In silico Studies of Sudanese Stem Bark Alcoholic Extract.

Introduction: Antimicrobial resistance is a critical global issue, and medicinal plants, as a key source of therapeutic agents, offer potential solutions by offering new antibacterial agents. tree, known as Al Kakamout in Sudan, is a significant source of Gum Arabic and has been traditionally used to treat bacterial diseases. This study aimed to investigate a hydro-ethanol extract of Kakamout stem bark through GC-MS analysis, evaluate its antibacterial activity against two standard bacterial strains, and conduct molecular docking and ADME studies.

Health Literacy and Medication Adherence Among Patients with Type 2 Diabetes in Jordan: A Cross-Sectional Study.

Background: Improving health literacy has been found to play a significant role in enhancing medication adherence in patients with type 2 diabetes.

Purpose: The present study aims to evaluate health literacy and its association with medication adherence among diabetic patients in Jordan.

Patients And Methods: This cross-sectional study included 400 diabetic patients, predominantly female (68.

Controlling the Apex in Early Onset Scoliosis Through Active Apex Correction (APC) Non Fusion Growth Modulating Technique, Is It a Myth?

Study Design: A multicenter retrospective study.

Objectives: To determine the rate of Apex facet fusion in children with Early Onset Scoliosis treated surgically with the Active Apex Correction (APC) technique.

Methods: Seventeen patients were treated with the APC technique as index surgery for Early Onset Scoliosis with more than 1 year of follow-up.

Heterotopic neuroglial mass in the parapharyngeal space causing dysphagia in a 4 years old child: A case report.

Introduction: Neuroglial heterotopia represents a rare differential diagnosis for pediatric neck masses. Its occurrence in the parapharyngeal space is exceptionally uncommon, with fewer than 30 documented cases in the literature.

Case Report: This report details the case of a 4-year-old girl initially noted to have a mass in the right parotid area at birth with no symptoms.

Identification of Variants in Pediatric Patients with Severe Early-Onset Obesity from Qatar.

The kinase suppressor of Ras 2 () gene is associated with monogenic obesity, and loss-of-function variants in have been identified in individuals with severe early-onset obesity. This study investigated variants in 9 pediatric patients with severe early-onset obesity in Qatar using whole genome sequencing among a cohort of 240 individuals. We focused on variants with a minor allele frequency (MAF) below 1% and a Combined Annotation Dependent Depletion (CADD) score above 13 to identify potential causative variants.

Neuroinflammation and Neurometabolomic Profiling in Fentanyl Overdose Mouse Model Treated with Novel β-Lactam, MC-100093, and Ceftriaxone.

Opioid-related deaths are attributed to overdoses, and fentanyl overdose has been on the rise in many parts of the world, including the USA. Glutamate transporter 1 (GLT-1) has been identified as a therapeutic target in several preclinical models of substance use disorders, and β-lactams effectively enhance its expression and function. In the current study, we characterized the metabolomic profile of the nucleus accumbens (NAc) in fentanyl-overdose mouse models, and we evaluated the protective effects of the functional enhancement of GLT-1 using β-lactams, ceftriaxone, and MC-100093.

Green Tea Polyphenol Nanoparticles Reduce Anxiety Caused by Tobacco Smoking Withdrawal in Rats by Suppressing Neuroinflammation.

Repeated exposure to tobacco smoke causes neuroinflammation and neuroplasticity, which correlates with smoking withdrawal-induced anxiety. The purpose of this study was to investigate the anticipated involvement of antioxidant-rich nanoparticles (NPs) prepared by oxidation-triggered polymerization of green tea catechins in impacting these effects in a rat model of tobacco smoke exposure. Exposure to tobacco smoke was carried out for 2 h a day, 5 days a week, for a total of 36 days.

Validation of an Arabic tool for assessing vaccination literacy: A factor and Rasch analysis.

Vaccine literacy is a significant part of health literacy. Although several tools have been developed to assess vaccine literacy, such tools are lacking in Arabic. Validating an Arabic version of a tool that evaluates vaccine literacy is critically important, as it would aid in understanding the decision-making process regarding vaccinations among individuals in Arabic-speaking countries.

Assessing mental health literacy in Jordan: a factor analysis and Rasch analysis study.

Background: Mental health literacy (MHL) research in Jordan is sparse and validated MHL measures are lacking. The present study validated a Jordanian version of the Mental Health Literacy Scale (MHLS) and examined Jordanian individuals' MHL.

Method: A Google Forms survey was designed, and the link was shared through various Jordanian social media platforms.