Topical anesthetic abuse keratopathy: a commonly overlooked health care problem.

Purpose: To evaluate the clinical course, treatment modality, factors affecting the epithelization period, and visual outcome in patients with topical anesthetic abuse keratopathy.

Methods: The medical records of 19 patients with a confirmed diagnosis of topical anesthetic abuse keratopathy were retrospectively examined; occupation, initiating event, biomicroscopic findings, treatment modality, epithelization period, and best-corrected visual acuity (BCVA) were noted. The Wilcoxon signed rank test was used to compare BCVA before and after treatment; P values <0.

In vivo confocal microscopic findings of 2 patients with Bietti crystalline corneoretinal dystrophy.

Purpose: To describe the clinical and in vivo confocal microscopic findings of the cornea in 2 patients with Bietti crystalline corneoretinal dystrophy using Heidelberg Retina Tomograph II Rostock Cornea Module.

Methods: Two women 25 and 33 years of age underwent ophthalmologic assessment, including fundus photography, optical coherence tomography, fluorescein angiography, electroretinography, and in vivo confocal microscopy.

Results: Slit-lamp examination revealed crystalline deposits at the superior limbus of the cornea in both of the subjects.

Ocular changes in primary hypothyroidism.

Background: To determine the ocular changes related to hypothyrodism in newly diagnosed patients without orbitopathy.

Findings: Thirty-three patients diagnosed to have primary overt hypothyroidism were enrolled in the study. All subjects were assigned to underwent central corneal thickness (CCT), anterior chamber volume, depth and angle measurements with the Scheimpflug camera (Pentacam, Oculus) and cup to disc ratio (C/D), mean retinal thickness and mean retinal nerve fiber layer (RNFL) thickness measurements with optical coherence tomography (OCT) in addition to ophthalmological examination preceeding the replacement therapy and at the 1(st), 3(rd )and 6(th )months of treatment.

Blood and lens lipid peroxidation and antioxidant status in normal individuals, senile and diabetic cataractous patients.

Purpose: Oxidative mechanisms are believed to play an important role in the pathogenesis of cataract, the most important cause of visual impairment at advanced age. To determine the body's antioxidant status as well as its lipid peroxidation levels, both blood and lens parameters were evaluated.

Methods: This study was performed on the blood samples and lenses obtained from 46 patients diagnosed as having cataract and 20 control subjects.