Conceptual Uncertainties and Practical Challenges in Voluntary Nagoya Protocol Compliance: The Australian Situation.

Amidst growing international pressure for institutions that collect biological material to comply with the Nagoya Protocol, scientific gatekeepers such as herbaria, funding bodies, and academic journals increasingly request proof of Nagoya Protocol compliance. What happens when research is conducted in a country which does not have a comprehensive regulatory framework implementing the Nagoya Protocol? This article addresses this question through an examination of the difficulties that genetic resource collectors and biobankers may encounter in attempting to voluntarily comply with the Nagoya Protocol in Australia, a country that has not ratified the Nagoya Protocol at a federal level. It summarizes the requirements of the Nagoya Protocol, surveys the legal and regulatory situation that currently exists in Australia, and outlines the difficulties and ambiguities encountered by scientists and biobankers in attempting to navigate this system.

Management of Failed Fixation of Extracapsular Hip Fractures.

Background Extracapsular hip fractures are routinely treated with fixation, and the majority heal without complication. The fixation fails in a minority of cases, typically either by 'cutting out' of the superior femoral head or through breakage of the metalwork following non-union. In such cases, if operative treatment is thought appropriate, there are two major treatment options: revision fixation of the fracture or joint replacement surgery.

A Meta-Analysis to Evaluate Implant Survival and Benefits of the Use of Dual Mobility Constructs in Total Hip Replacement Following Hip Fracture.

Total hip replacement (THR) is commonly performed to treat hip fractures. Dual-mobility constructs (DMCs) are increasingly used for this indication. The aim of this study was to use evidence synthesis techniques to estimate net all-cause construct survival for THR with DMC performed for hip fracture.

Survivorship of the dual-mobility construct in elective primary total hip replacement: a systematic review and meta-analysis including registry data.

Introduction: Dislocation is a common complication associated with total hip replacement (THR). Dual-mobility constructs (DMC-THR) may be used in high-risk patients and have design features that may reduce the risk of dislocation. We aimed to report overall pooled estimates of all-cause construct survival for elective primary DMC-THR.

Quality of fracture reduction is associated with patient survival at one year, but not 30 days, following trochanteric hip fracture fixation. A retrospective cohort study.

Introduction: Few studies have been performed to evaluate the association between technical surgical factors and patient outcomes following hip fracture surgery. We performed a retrospective cohort study of elderly patients who had undergone fixation of trochanteric hip fractures using a sliding hip screw (SHS), with the aim of establishing whether there was a correlation between quality of fracture reduction and mortality at 30 days and one year.

Patients And Methods: A retrospective cohort study was designed.

Using a Wearable Activity Monitor to Accurately Measure Mobility After Surgery for Hip Fractures (MASH)-A Feasibility Study Protocol.

Introduction: Hip fractures are the most common reason for acute orthopaedic admission in the United Kingdom (UK) and pose a substantial cost to the National Health Service (NHS). A significant proportion of this expenditure is accounted for by hospital bed days, with additional contributions from health and social aftercare. Early ambulation following hip fracture surgery improves outcomes by accelerating functional recovery and reducing the need for ongoing care.

Safety Considerations in 3D Bioprinting Using Mesenchymal Stromal Cells.

Three-dimensional (3D) bioprinting has demonstrated great potential for the fabrication of biomimetic human tissues and complex graft materials. This technology utilizes bioinks composed of cellular elements placed within a biomaterial. Mesenchymal stromal cells (MSCs) are an attractive option for cell selection in 3D bioprinting.

Autologous cell-free serum preparations in the management of knee osteoarthritis: what is the current clinical evidence?

Background: There is paucity in the current literature regarding clinical outcomes of autologous cell-free serum preparations. The objective of this paper is to collate the clinical evidence and review the results of intraarticular injections of autologous cell-free serum preparations in the management of knee osteoarthritis (OA).

Methods: A comprehensive English literature search was undertaken using the healthcare database website (https://hdas.

Patients with Clinically Suspected but Unproven Hip Fractures, Who Require Cross-Sectional Imaging, Are Best Initially Admitted under Geriatrician-Led Care-A Retrospective Review.

Patients with suspected hip fractures who require further imaging to confirm or disprove the diagnosis may be admitted to orthopaedic or medical departments. We aim to provide evidence regarding the appropriate admission pathway for such patients. This is a retrospective study of all suspected hip fracture patients receiving second-line imaging between 1 January 2015 to 30 June 2016 in one hospital trust.

Using an original triage and on call management tool aids identification and assessment of the acutely unwell surgical patient.

Until now, there have been no published surgical triage tools. We have developed the first such tool with a tiered escalation policy, aiming to improve identification and management of critically unwell patients. The existing sheet which is used to track new referrals and admissions to the surgical assessment unit was reviewed.

Improving documentation in surgical operation notes.

Background: Accurate documentation in surgical operation notes is crucial in facilitating the postoperative care of surgical patients and forms an important medicolegal document. This study audited the quality and completeness of documentation in surgical operation notes at a single district general hospital against the Royal College of Surgeons (2014) Good Surgical Practice guidelines, and looked to improve clinical practice through improved compliance with these guidelines.

Method: A total of 101 operation notes were audited from a variety of surgical specialities in November 2014 (cycle 1) and 100 notes in May 2015 (cycle 2).