A three-dimensional printed photopolymer resin implant for orbital rehabilitation for evisceration.

Purpose: To evaluate the biocompatibility of three-dimensional (3D) printed orbital spheres for evisceration.

Materials: A total of 10 consecutive patients (eight females and two males; mean age, 46.8 ± 14.

Hyoscine butylbromide for colorectal polyp detection: prospective, randomized, placebo-controlled trial.

Objectives:: The removal of pre-malignant colorectal lesions prevents cancer. Hyoscine has been proposed as a means of improving diagnosis by reducing colonic movements. The aim of this study was to analyze whether this anti-spasmodic enhances the detection of pre-malignant colorectal lesions.

Comparative analysis of endoscopic and histopathological features of superficial elevated lesions resected by endoscopic mucosal resection in the distal and proximal colon.

Objective: to compare endoscopic and histopathologic features of superficial, elevated lesions with one or more centimeters in diameter, diagnosed by videocolonoscopy on the distal and proximal colon, and subjected to mucosal resection.

Methods: we conducted a retrospective, cross-sectional, observational study involving 8,075 videocolonoscopies. From this total, we evaluated 166 mucosectomies in 145 patients with superficial, elevated lesions with a diameter equal to or greater than 1cm.

Femtosecond-assisted intrastromal corneal ring implantation for keratoconus treatment: a comparison with crosslinking combination.

Purpose: To compare visual outcomes, corneal astigmatism, and keratometric readings in patients with keratoconus who underwent intrastromal corneal ring implantation (ICRSI) alone with those who underwent ICRSI combined with ultraviolet A riboflavin-mediated corneal collagen crosslinking (CXL).

Methods: Pre- and post-operative best-corrected distance visual acuity (BCDVA), spherical error, cylindrical error, and mean keratometry were retrospectively compared over a period of 2 years in patients with keratoconus who underwent only ICRSI (group 1) versus those in patients who underwent combined ICRSI-CXL (group 2).

Results: Thirty-two eyes of 31 patients were evaluated.

[Femtosecond laser versus mechanical microkeratome for LASIK flap creation].

Purpose: To assess LASIK flaps made by femtosecond laser and mechanical microkeratome.

Methods: Clinical, prospective, randomized, masked study of 32 eyes (16 patients). Both eyes of all patients were operated, each patient underwent different techniques for lasik.

[Patients with astigmatism who underwent cataract surgery by phacoemulsification: toric IOL x asferic IOL?].

Purposes: Compare the visual acuity of patients who underwent cataract surgery by phacoemulsification with IOL AcrySof(®) toric implantation versus AcrySof(®) IQ and evaluate the reduction of cylindrical diopters (CD) in the postoperative period.

Methods: Analytical and retrospective study of 149 eyes with 1 or more diopters of regular symmetrical keratometric astigmatism, which underwent cataract surgery by phacoemulsification. The eyes were divided into two groups: the toric group with 85 eyes and the non-toric group with 64 eyes.

[Experimental study of new material for biocompatibility as orbital implant].

To evaluate the resin FullCure 720® biocompatibility as orbital implant. Clinical response and signs of systemic toxicity to the resin were evaluated, local biocompatibility and microscopic analysis regarding chronic local inflammatory response to the implant. The animals were weighted, biochemical exams and inflammatory response were evaluated.

Impact of collagen crosslinking on corneal sensitivity in keratoconus patients.

Purpose: To evaluate changes in corneal sensitivity after corneal collagen crosslinking in patients having progressive keratoconus.

Methods: Thirty-six consecutive patients having progressive keratoconus were included in the study. The crosslinking surgery was performed in one eye of each patient (study group) and the opposite eye was used as control (control group).

Modified femtosecond laser-assisted sutureless anterior lamellar keratoplasty.

A variation of the femtosecond laser-assisted sutureless anterior lamellar keratoplasty technique using a femtosecond laser incision for surgical management of anterior corneal disease is described. Six patients with corneal scars were treated with the laser to create a horizontal lamellar bed interface in the cornea of the donor and recipient eyes, with a manual partial-thickness vertical trephination to complete the excisions. This technique allows matching of donor and host tissue dimensions with precise tissue apposition and greater surface area for healing.

Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery.

Purpose: To evaluate the accuracy of intraocular lens (IOL) power calculations with A-constant optimization in Descemet's stripping automated endothelial keratoplasty (DSAEK) combined with cataract extraction and intraocular lens implantation (DSAEK triple procedure).

Design: Retrospective case series.

Participants: Thirty eyes of 22 patients with Fuchs' endothelial dystrophy who underwent the DSAEK triple procedure performed by a single surgeon.

Efficacy and safety of travoprost 0.004%/timolol 0.5% fixed combination as transition therapy in patients previously on prostaglandin analog monotherapy.

Purpose: To assess the safety and efficacy of transitioning patients whose intraocular pressure (IOP) had been insufficiently controlled on prostaglandin analog (PGA) monotherapy to treatment with travoprost 0.004%/timolol 0.5% fixed combination with benzalkonium chloride (TTFC).

The effect of subconjunctival bevacizumab on corneal neovascularization, inflammation and re-epithelization in a rabbit model.

Purpose: To evaluate the use of subconjunctival bevacizumab on corneal neovascularization in an experimental rabbit model for its effect on vessel extension, inflammation, and corneal epithelialization.

Methods: In this prospective, randomized, blinded, experimental study, 20 rabbits were submitted to a chemical trauma with sodium hydroxide and subsequently divided into two groups. The experimental group received a subconjunctival injection of bevacizumab (0.

[Effect of subconjunctival bevacizumab on corneal neovascularization and reepithelization 25 days after chemical burn].

Purposes: To evaluate the effect of subconjunctival bevacizumab in an experimental model of neovascularization in rabbit cornea. Determine its effect on vessels extension, inflammation, epithelialization of the cornea and whether the evaluation method used is appropriate to compare neovascular models.

Methods: Experimental, prospective, randomized, blinded study in twenty rabbits subjected to chemical trauma with sodium hydroxide at 1N divided into two groups.

[CBO/ALCON teaching method of phacoemulsification: results of Hospital de Olhos do Paraná].

Purpose: To analyze the results obtained with a new phacoemulsification teaching method in the specialization course of Hospital de Olhos do Paraná.

Methods: A retrospective study evaluated the results of a "reversal" method used in the CBO/ALCON teaching program at the Hospital de Olhos do Paraná. The method is based on the student progression through five checkpoints starting from the end of the surgery towards the beginning and analysis of intra- and postoperative complications at each one of the checkpoints.

[Asymmetric intrastromal corneal ring for the treatment of keratoconus].

Purpose: To analyze corneal curvature and visual acuity after asymmetric intrastromal corneal rings implantation, not following the nomogram proposed by the manufacturer.

Methods: Seven eyes of seven keratoconus patients which had asymmetric corneal rings implanted in their corneal stroma were studied.

Results: A flattening of the average corneal keratometry was noted in all patients, as well as an increase of the postoperative corneal asymmetry.

[Technique for separating Descemet membrane for corneal endothelial cells transplantation: experimental study in rabbits].

Purpose: To evaluate the percentage of endothelial cell damage induced during a surgical technique of Descemet's membrane separation containing healthy endothelium, analyze the viability and efficacy of this technique, and evaluate the percentage of endothelial cell damage caused by inversion of the cornea on an artificial anterior chamber.

Methods: The corneas from three groups of 12 New Zealand rabbits were evaluated. The Group one was used as the control, so the corneas were analyzed after collected and trephinated.

[Snellen visual acuity evaluation].

Purpose: To evaluate the visual acuity (VA) measurement by Snellen chart at three main Ophthalmology centers in Curitiba, compare these measurements with a computerized method for calibrating VA and also with the standard theory developed by Hermann Snellen.

Methods: Descriptive study including 15 Ophthalmology clinics and a computerized method to measure the VA. Using a tape measure and a caliper, measurement of the distance was obtained from the sitting patients' eye to VA optotypes projection on the wall.

[Citophotometric expression of the factor of cellular proliferation ki-67 in the goiter colloid and in the papillary carcinoma of the thyroid].

Objective: To compare the cytophotometric quantitative expression of Ki-67 cellular proliferation factor in the colloid goiter with papillary carcinoma of the thyroid.

Methods: The protein Ki-67 was studied with immunohistochemistry in 20 cases of papillary carcinoma of the thyroid and 12 cases of colloid goiter. The immunomarked cell nuclei were quantified through the software SAMBA 4000 and analyzed by software IMMUNO, considering variables index marker and optical density.

Visual performance after toric IOL implantation in patients with corneal astigmatism.

Purpose: To analyze visual acuity without correction and rotational stability outcomes following toric IOL implantation.

Methods: Prospective study of 20 eyes of 13 patients that underwent phacoemulsification surgery indicated for cataract associated with regular keratomeric astigmatism, symmetrical, ranging from 1 to 4 diopters. Best corrected visual acuity, refraction, keratometry and computed topography were performed preoperatively.

[Evaluation of the quality of donor corneas in relation to the age of donor and cause of death].

Purpose: To analyze the quality of the corneas evaluated by slit lamp examination in the Eye Bank of the Hospital de Clínicas UFPR and its relation to donor age and cause of death.

Methods: Analysis of 492 corneas, evaluated in BTO HC-UFPR between August 2006 to August 2008. Each cornea was classified regarding the quality as: very good, good, regular and bad; and according to clarity, epithelial defect, stromal edema, Descemet's folds, stromal opacity, corneal scarring, endothelial density and guttata.

[The main factors related with cornea non-donation of potential donors in a university hospital of Curitiba].

Purpose: To define the main factors related with cornea non-donation of potential donors in a University Hospital of Curitiba.

Methods: The potential corneal donators who died at the I.C.

[Influence of corneal astigmatism in final visual acuity after implantation of AcrySof ReSTOR: case report].

Currently, new types of intraocular lenses have been developed aiming to eliminate presbyopia and the use has become more popular. The authors report the case of a patient with bilateral cataract and corneal irregularities and astigmatism higher than 2D in the corneal topography, in which AcrySof ReSTOR intraocular lens was implanted in the left eye associated to relaxing limbal incisions trying to reduce corneal astigmatism. The near and distance postoperative visual acuity were worse than expected, with no improvement with refraction.

[Total testosterone level in postmenopausal women with dry eye].

Purpose: The purpose of this study was to compare total testosterone blood level among three groups of postmenopausal women: control, mild to moderate dry eye and severe dry eye.

Methods: Twenty-nine postmenopausal women were selected. The exclusion criteria were: hormone replacement therapy in the last 8 weeks, mechanical palpebral abnormalities, pterygium, lacrimal obstructions, intraocular inflammation or contact lens use.