Using Platelet-Rich Fibrin in Combination With Allograft Bone Particles Can Induce Bone Formation in Maxillary Sinus Augmentation.

Background: Sinus pneumatization secondary to posterior maxillary tooth extraction can hinder proper implant installation. Maxillary sinus floor augmentation is a surgical procedure that has been proposed to overcome this issue.

Purpose: The aim of this study was to evaluate and compare the histomorphometric outcomes of sinus floor elevation using allograft bone particles with or without platelet-rich fibrin (PRF).

Marginal bone loss around crestal or subcrestal dental implants: prospective clinical study.

Objectives: The stability of crestal bone has been reported as a major factor in the success of dental implants. Implants can be placed in an equicrestal (crestal) or subcrestal position. The aim of this study was to evaluate the effect of implant depth placement on marginal bone loss.

Evaluation of the Topical Effect of Probiotic Mouthwash in the Treatment of Patients with Peri-Implant Mucositis.

Peri-implant mucositis is a reversible inflammatory process of the soft tissue surrounding a dental implant. If left untreated, peri-implant mucositis can evolve into peri-implantitis, which leads to the loss of the supporting bone around the implant. The treatment of peri-implantitis is of special importance, since peri-implantitis can be very expensive and troublesome for both the patient and the dentist and a lack of complete resolution can lead to a low probability of implant success.

A novel mutation in the cathepsin C (CTSC) gene in Iranian family with Papillon-Lefevre syndrome.

Objectives: In this study, we analyzed the whole exomes of CTSC gene in a family with history of PLS.

Materials And Methods: Genomic DNA was extracted from peripheral blood and genotype analysis was performed. The mutated protein sequence was used to find the best possible tertiary structure for homology modeling.

The evaluation of implant stability measured by resonance frequency analysis in different bone types.

Objectives: Bone density seems to be an important factor affecting implant stability. The relationship between bone density and primary and secondary stability remains under debate. The aim of this study was to compare primary and secondary stability measured by resonance frequency analysis (RFA) between different bone types and to compare implant stability at different time points during 3 months of follow-up.

Evaluation of Alveolar Crest Changes following Buccal Bone Overbuilding in Immediate Implantation.

The aim of the present study was to evaluate alveolar crest changes when using demineralized freeze-dried bone allograft (DFDBA) and resorbable membrane between flap and buccal bone in addition to filling the gap, as compared to merely filling the gap, when performing immediate implantation. In 18 patients with 24 single-root teeth, implants were placed immediately after extraction. In the test group (nine patients with 12 teeth), DFDBA and barrier membrane were placed between buccal crest and flap after implant placement.

Comparison of Two Regenerative Surgical Treatments for Peri-Implantitis Defect using Natix Alone or in Combination with Bio-Oss and Collagen Membrane.

The aim of this clinical trial was to evaluate 6-month clinical and radiographic outcomes after surgical regenerative therapy of peri-implantitis lesions using either porous titanium granules (Natix, Tigran Technologies, Malmo, Sweden) alone or bovine bone mineral (Bio-Oss, Giestlich, Wolhusen, Switzerland) with a collagen membrane (B&B Dental Implant Company, San Pietro, Italy). Twenty-four patients having at least one implant with a peri-implantitis lesion were involved in this study. Patients were assigned randomly into two groups and treated with two different regenerative approaches.

Evaluation of the effects of subgingival injection of Simvastatin on space re-opening after orthodontic space closure in adults.

Background. This clinical trial evaluated the effect of Simvastatin on space re-opening after orthodontic space closure and its effect on the gingival index (GI) and clinical attachment loss (CAL). Methods.

Protein modeling of cathepsin C mutations found in Papillon-Lefèvre syndrome.

Background: Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder characterized by hyperkeratosis involving the palms, soles, elbows, and knees followed by periodontitis, destruction of alveolar bone, and loss of primary and permanent teeth. Mutations of the lysosomal protease cathepsin C gene (CTSC) have been shown to be the genetic cause of PLS. This study analyzed CTSC mutations in five Iranian families with PLS and modeled the protein for mutations found in two of them.

In vitro antimicrobial comparison of chlorhexidine, persica mouthwash and miswak extract.

Aim: Herbal mouthwashes, such as persica (Salvadora persica, mint and yarrow extracts) and miswak extract have been shown to decrease gingival inflammation and plaque accumulation. The aim of this study was to compare the antimicrobial activities of persica and miswak extract with the conventional mouthwash chlorhexidine against Streptococcus salivarius, Streptococcus sanguis, Lactobacillus vulgaris and Candida albicans.

Materials And Methods: In this in vitro study, blood-agar culture (Merk, Germany) was used to grow the streptococcus strains, saburd-dextrose culture (Merk, Germany) was used to grow C.

The effect of periodontal treatment on IL-6 production of peripheral blood monocytes in aggressive periodontitis and chronic periodontitis patients.

Background: Several cytokines, including IL-6 have been implicated in the pathogenesis of periodontal disease. It is established that monocytes from periodontitis subjects show an increased production of IL-6 as compared to healthy subjects. However, little is known about the effect of periodontal treatment on IL-6 production by monocytes in subsets of periodontitis patients.