Gastrointestinal Basidiobolomycosis in Pediatric Cases With Multiple-Site Involvement: A Case Series.

Basidiobolomycosis, a rare fungal infection seen in immunocompetent patients, is a chronic granulomatous infection affecting the skin and subcutaneous tissue. It is caused by the fungus . Gastrointestinal basidiobolomycosis usually has non-specific clinical manifestations, and its diagnosis requires a high index of suspicion.

Exosomal Liquid Biopsy in Prostate Cancer: A Systematic Review of Biomarkers for Diagnosis, Prognosis, and Treatment Response.

Prostate cancer, a leading cause of cancer-related mortality among men, often presents challenges in accurate diagnosis and effective monitoring. This systematic review explores the potential of exosomal biomolecules as noninvasive biomarkers for the diagnosis, prognosis, and treatment response of prostate cancer. A thorough systematic literature search through online public databases (Medline via PubMed, Scopus, and Web of science) using structured search terms and screening using predefined eligibility criteria resulted in 137 studies that we analyzed in this systematic review.

Effect of fenofibrate on residual beta cell function in adults and adolescents with newly diagnosed type 1 diabetes: a randomised clinical trial.

Aims/hypothesis: Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, shows some promise in alleviating beta cell stress and preserving beta cell function in preclinical studies of type 1 diabetes. The aim of this phase 2, placebo-controlled, double-blinded, randomised clinical trial was to investigate the efficacy and safety of fenofibrate in adults and adolescents with newly diagnosed type 1 diabetes.

Methods: We enrolled 58 individuals (aged 16 to 40 years old) with newly diagnosed type 1 diabetes and randomised them to daily oral treatment with fenofibrate 160 mg or placebo for 52 weeks (in a block design with a block size of 4, assigned in a 1:1 ratio).

Evaluating the Response of the Soil Bacterial Community and Lettuce Growth in a Fluorine and Cadmium Co-Contaminated Yellow Soil.

The impact of cadmium (Cd) and fluorine (F) on plant and human health has provoked significant public concern; however, their combined effects on plant and soil bacterial communities have yet to be determined. Here, a pot experiment was conducted to evaluate the effects of exogenous F, Cd, and their combination (FCd) on lettuce growth and soil bacterial communities. The results revealed that F and Cd concentrations in lettuce ranged from 63.

Functionality of wheat straw-derived biochar enhanced its efficiency for actively capping Cd and Pb in contaminated water and soil matrices: Insights through batch adsorption and flow-through experiments.

The impact of functionality of biochar on pressing environmental issue of cadmium (Cd) and lead (Pb) co-contamination in simultaneous soil and water systems has not sufficiently reported. This study investigated the impact of Fe- and Mg-functionalized wheat straw biochar (Fe-WSBC and Mg-WSBC) on Cd and Pb adsorption/immobilization through batch sorption and column leaching trials. Importantly, Fe-WSBC was more effective in adsorbing Cd and Pb (82.

Predicting the governing factors for the release of colloidal phosphorus using machine learning.

Predicting the parameters that influence colloidal phosphorus (CP) release from soils under different land uses is critical for managing the impact on water quality. Traditional modeling approaches, such as linear regression, may fail to represent the intricate relationships that exist between soil qualities and environmental influences. Therefore, in this study, we investigated the major determinants of CP release from different land use/types such as farmland, desert, forest soils, and rivers.

A Modified Model for Quantitative Heavy Metal Source Apportionment and Pollution Pathway Identification.

Current source apportionment models have successfully identified emission sources and quantified their contributions. However, when being utilized for heavy metal source apportion in soil, their accuracy needs to be improved, regarding migration patterns. Therefore, this work intended to improve the pre-existing principal component analysis and multiple linear regression with distance (PCA-MLRD) model to effectively locate pollution pathways (traffic emissions, irrigation water, atmospheric depositions, etc.

Mitigating cadmium exposure risk in rice with foliar nano-selenium: Investigations through Caco-2 human cell line in-vivo bioavailability assay.

The contamination of paddy fields by cadmium and lead is a major issue in China. The consumption of rice grown in heavy metals contaminated areas poses severe health risks to humans, where bioavailability and bioaccessibility remains the critical factor for risk determination. Selenium nanoparticles (Se-NPs) can mitigate the toxicity of heavy metals in plants.

Enhancing the phytoextraction efficiency of heavy metals in acidic and alkaline soils by Sedum alfredii Hance: A study on the synergistic effect of plant growth regulator and plant growth-promoting bacteria.

Plant growth regulators (PGR) and plant growth-promoting bacteria (PGPB) have the potential in phytoremediation of heavy metals (HMs) contaminated soils. However, their sole application may not yield the optimal results, thus necessitating the combined application. The present study aimed to enhance the phytoremediation efficiency of Sedum alfredii Hance (S.

Multidisciplinary Management of Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) Syndrome in an Adolescent With Complex Congenital Anomalies: A Case Report.

Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome presents with complex diagnostic and therapeutic challenges and is characterized by uterine didelphys, obstructed hemivagina, and ipsilateral renal anomaly. A 14-year-old female with a history of anorectal malformation and urogenital sinus anomaly presented with menstrual blood in her urine, abdominal pain, and distension. Investigations revealed a bicornuate uterus, vesicovaginal fistula, and right ovarian cyst, leading to the diagnosis of OHVIRA syndrome.

Occurrence of micropollutants in rural domestic wastewater in Zhejiang Province, China and corresponding wastewater-based epidemiology analysis.

By 2021, rural regions in China were occupied by over 500 million residents, generating an annual volume of 19.5 billion m of rural domestic wastewater (RDW). This study aimed to investigate the occurrence and removal of micropollutants (MPs) in RDW treatment facilities and to perform a corresponding wastewater-based epidemiology analysis (WBE).

Impact of Diabetic Foot Ulcer on the Health-Related Quality of Life of Diabetic Patients in Khartoum State.

Background This is a novel study from Sudan aimed at comparing health-related quality of life (HRQoL) between diabetic foot ulcer (DFU) patients and diabetes patients without DFU. Additionally, this study aimed to determine the factors correlating with lower HRQoL. Methodology A descriptive, cross-sectional study with a comparative group was conducted in three diabetes centers in Khartoum, Sudan, in 2020.

Co-foliar application of zinc and nano-silicon to rice helps in reducing cadmium exposure risk: Investigations through in-vitro digestion with human cell line bioavailability assay.

Foliar application of zinc (Zn) or silicon nanoparticles (Si-NPs) may exert regulatory effects on cadmium (Cd) accumulation in rice grains, however, their impact on Cd bioavailability during human rice consumption remains elusive. This study comprehensively investigated the application of Zn with or without Si-NPs in reducing Cd accumulation in rice grains as well to exactly evaluate the potential risk of Cd exposure resulting from the rice consumption by employing field experiment as well laboratory bioaccessibility and bioavailability assay. Sole Zn (ZnSO) or in combination with Si (ZnSO +Si and ZnO+Si) efficiently lowered the Cd concentration in rice grains.

Transforming Bariatric Surgery Outcomes: The Pivotal Role of Enhanced Recovery After Surgery (ERAS) Protocols in Patient-Centered Care.

Bariatric surgery is a critical strategy in managing morbid obesity. Enhanced recovery after surgery (ERAS) protocols have revolutionized perioperative care in this field. This systematic review aims to synthesize current evidence on the impact of ERAS protocols on patient-centered outcomes in bariatric surgery.

Seed nano-priming with multiple nanoparticles enhanced the growth parameters of lettuce and mitigated cadmium (Cd) bio-toxicity: An advanced technique for remediation of Cd contaminated environments.

Seed nano-priming can be used as an advanced technology for enhancing seed germination, plant growth, and crop productivity; however, the potential role of seed nano-priming in ameliorative cadmium (Cd) bio-toxicity under Cd stress has not yet been sufficiently investigated. Therefore, in this study we investigated the beneficial impacts of seed priming with low (L) and high (H) concentrations of nanoparticles including nSiO (50/100 mg L), nTiO (20/60 mg L), nZnO (50/100 mg L), nFeO (100/200 mg L), nCuO (50/100 mg L), and nCeO (50/100 mg L) on lettuce growth and antioxidant enzyme activities aiming to assess their efficacy for enhancing plant growth and reducing Cd phytotoxicity. The results showed a significant increase in plant growth, biomass production, antioxidant enzyme activities, and photosynthetic efficiency in lettuce treated with nano-primed nSiH + Cd (100 mg L), nTiH + Cd (60 mg L), and nZnL + Cd (50 mg L) under Cd stress.

Federated Learning Approach for Secured Medical Recommendation in Internet of Medical Things Using Homomorphic Encryption.

The concept of Federated Learning (FL) is a distributed-based machine learning (ML) approach that trains its model using edge devices. Its focus is on maintaining privacy by transmitting gradient updates along with users' learning parameters to the global server in the process of training as well as preserving the integrity of data on the user-end of internet of medical things (IoMT) devices. Instead of a direct use of user data, the training which is performed on the global server is done on the parameters while the model modification is performed locally on IoMT devices.

Foliar application of plant growth regulators for enhancing heavy metal phytoextraction efficiency by Sedum alfredii Hance in contaminated soils: Lab to field experiments.

The phytoremediation efficiency of plants in removing the heavy metals (HMs) might be influenced by their growth status and accumulation capacity of plants. Herein, we conducted a lab-scale experiment and a field try out to assess the optimal plant growth regulators (PGRs) including indole-3-acetic acid (IAA)/brassinolide (BR)/abscisic acid (ABA) in improving the phytoextraction potential of Sedum alfredii Hance (S. alfredii).

Oncological Horizons: The Synergy of Medical and Surgical Innovations in Cancer Treatment.

The landscape of cancer treatment has witnessed a remarkable transformation in recent years, marked by the convergence of medical and surgical innovations. Historically, cancer therapy faced challenges, including limited efficacy and severe side effects. This narrative review explores the historical progression of cancer treatments, shedding light on significant breakthroughs in both medical and surgical oncology.

Orbital Onset: The Intricate Journey From Ear Abscess to Cavernous Sinus Thrombosis in a Diabetic Male.

Cavernous sinus thrombosis (CST) is a rare, yet severe condition often linked to infections in the nasal and facial areas. We present a case of a 43-year-old male farmer with diabetes who initially showed ear abscess symptoms that progressed to vision loss and CST-like symptoms. Self-treatment and an unidentified medication regimen may have worsened his condition.

Gallbladder Mysteries: A Diagnostic Dilemma in Mirizzi Syndrome With Acalculous Presentation.

Mirizzi syndrome (MS) is an uncommon condition caused by chronic gallbladder stones, leading to external compression and obstruction of the common hepatic duct. This report details an unusual MS case in a 65-year-old man who experienced right upper abdominal pain, jaundice, fever, and nausea. Diagnostic tests, such as ultrasound and CT scan, indicated acute acalculous cholecystitis resembling MS.

Effect of foliar application of nanoparticles on growth, physiology, and antioxidant enzyme activities of lettuce (Lactuca sativa L.) plants under cadmium toxicity.

Nanotechnology has attracted the interest of scientists due to its wide range of application specifically in agriculture. Nanoparticles (NPs) may act as a promising materials to alleviate cadmium (Cd) stress in plants. This study aims to assess the impact of multiple nanoparticles including nSiO (50 mg L:100 mg L), nTiO (20 mg L:60 mg L), nZnO (50 mg L:100 mg L), nFeO (100 mg L:200 mg L), nCuO (50 mg L:100 mg L), and nCeO (50 mg L:100 mg L) in combination with CdCl (5 µM) to mitigate Cd toxicity in lettuce through foliar application in hydroponic solution.

Seed priming with nano-silica effectively ameliorates chromium toxicity in Brassica napus.

Plant yield is severely hampered by chromium (Cr) toxicity, affirming the urgent need to develop strategies to suppress its phyto-accumulation. Silicon dioxide nanoparticles (SiO NPs) have emerged as a provider of sustainable crop production and resistance to abiotic stress. But, the mechanisms by which seed-primed SiO NPs palliate Cr-accumulation and its toxic impacts in Brassica napus L.