Epithelial cells/progenitor cells in developing human lower respiratory tract: Characterization and transplantation to rat model of pulmonary injury.

Introduction: For cell-based therapies of lung injury, several cell sources have been extensively studied. However, the potential of human fetal respiratory cells has not been systematically explored for this purpose. Here, we hypothesize that these cells could be one of the top sources and hence, we extensively updated the definition of their phenotype.

Design and fabrication of polycaprolactone/gelatin composite scaffolds for diaphragmatic muscle reconstruction.

Diaphragmatic wall defects caused by congenital disorders or disease remain a major challenge for physicians worldwide. Polymeric patches have been extensively explored within research laboratories and the clinic for soft tissue and diaphragm reconstruction. However, patch usage may be associated with allergic reaction, infection, granulation, and recurrence of the hernia.

Partial replacement of left hemidiaphragm in dogs by either cryopreserved or decellularized heterograft patch.

Objectives: Large diaphragmatic defects are still a challenging issue for reconstruction using either synthetic prosthesis or bioprosthesis. To evaluate the possibility of using diaphragm allograft as a natural bioprosthesis in humans, we conducted a two-group study and compared cryopreserved and decellularized diaphragmatic heterograft patched in a canine model.

Methods: At the end of organ harvesting from a human donor, the left hemidiaphragm was taken to the laboratory in phosphate-buffered saline solution.

Successful airway management in a patient with tracheal stenosis and tracheoesophageal fistula: a case report.

A twenty-year-old girl was referred with tracheal stenosis (TS) which was a consequence of prolonged intubation after head injury because of previous car accident. The patient was aphasic and had normal respiration. Fiberoptic bronchoscopy showed complete tracheal obstruction at second tracheal ring level.

Pancreas transplantation in shiraz organ transplant center; the first Iranian experience.

Background: Pancreas transplantation is the treatment of choice for selected patients with type 1 diabetes mellitus. We reviewed our first 40 patients who underwent pancreas transplantation in Shiraz Organ Transplant Center.

Methods: Between April 2006 and April 2008, we performed pancreas transplantation on 40 recipients.

Outcome of kidney transplantation in patients with polycystic kidney disease: a single center study.

Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of end-stage renal disease and a common indication for renal transplantation. Patients with ADPKD show some differences in graft outcome and complications following renal transplantation. This study was undertaken to evaluate the demographics, outcome and complications of renal transplantation in patients with ADPKD.

The comparison of clinical and biochemical parameters among 1200 alive and dead renal transplant recipients.

With increasing long-term graft survival and life-long immunosuppression, cardiovascular disease and infectious complications are major causes of morbidity and mortality. We retrospectively evaluated 1200 consecutive kidney transplant patients at Shiraz Organ Transplant Center from December 1988 to December 2003. Data on demographic profile, donor source, blood pressure, rejection episodes, cause of death, and hematological and biochemical serum profiles were collected to compare alive and dead recipients.

Pediatric liver transplantation in Iran: evaluation of the first 50 cases.

LT is nowadays accepted as the definitive therapy for end-stage liver disease. We report our experiences with pediatric LT using grafts from living related and DD. From April 1999 to March 2006, 50 infants and children who underwent LT were studied for pretransplantation status, medical and surgical complications and survival rate.

Transplantation of a horseshoe kidney.

Experience with horseshoe kidney transplantation is limited. Horseshoe kidney may be underutilized for transplantation because of the greater incidence of vascular and other associated urological anomalies. Nowadays, owing to a greater number of patients waiting for a kidney donation and to a shortage of organs donated, more suitable organ acceptance criteria have been formulated.

Determination of the incidence and severity of hoarseness after cardiac surgery.

Background: The aim of the study was to determine the incidence and severity of hoarseness and vocal cord dysfunction in 200 patients undergoing open heart surgery in Shiraz-Iran.

Material/methods: This study involved prospective evaluation of 200 patients who underwent open heart surgery during the year 2003 in Shiraz University hospitals. All patients received the same standard anesthetic technique.

Outcome of mucormycosis in liver transplantation: four cases and a review of literature.

Mucormycosis is a rare but highly invasive fungal infection that occurs in transplant recipients. The literature contains descriptions of 12 cases of mucormycosis after orthotopic liver transplantation (OLT). This report describes the fatal courses in four patients at our center who developed mucormycosis after liver transplantation.