Publications by authors named "Hamid El Amri"

Article Synopsis
  • - This study explored the genetic, chemical, and biological properties of ten traditional Moroccan seed varieties, identifying two unique molecular profiles through DNA analysis and discovering a new gene sequence related to THCA synthase.
  • - Chemical analysis revealed a total of 37 compounds, including 13 non-volatile chemicals (like inactive cannabinoids and polyphenols) and 24 volatile compounds, with 7 of these being newly identified in seed extracts.
  • - The research also assessed the seeds' biological activities, showcasing their antioxidant, antimicrobial, cytotoxic, and potential antiviral effects, suggesting these seeds could be valuable for future nutritional and health-related studies.
View Article and Find Full Text PDF

Background: LMTK3 and AKT1 each have a role in carcinogenesis and tumor progression. The analysis of single nucleotide polymorphisms of AKT1 and LMTK3 could lead to more complete and accurate risk estimates for colorectal cancer.

Aim: We evaluated the association between single nucleotide polymorphisms (SNPs) of AKT1 and LMTK3 and the risk of colorectal cancer in a case-control study in Moroccan population.

View Article and Find Full Text PDF

The abnormal activation of AKT/mTOR signaling pathway and overexpression of LMTK3, are the main factors involved in the generation of drug resistance. Therefore, the use of computer-aided drug design in the inhibitors discovery offers an advantage to provide new candidates for the treatment of this resistance. We realised the virtual screening and molecular docking of AKT1 and LMTK3 proteins by the Dockblaster server.

View Article and Find Full Text PDF
Article Synopsis
  • - A collaborative exercise involving multiple labs was conducted to evaluate how effectively different laboratories can analyze DNA from old bone samples, specifically those around 150 and 400 years old, supplied by institutions in Prague.
  • - Eighteen participating laboratories used various techniques for DNA typing, and while they achieved consistent results for the 150-year-old sample, the 400-year-old sample presented challenges due to its degraded condition.
  • - The study highlights the importance for labs to routinely check their methods for identifying degraded DNA in bone and teeth samples, ensuring minimal contamination risks during the process.
View Article and Find Full Text PDF

Background: Anaplasma phagocytophilum is an emerging tick-borne zoonotic pathogen of increased interest worldwide which has been detected in northern Africa. Anaplasma platys is also present in this region and could possibly have a zoonotic potential. However, only one recent article reports on the human esposure to A.

View Article and Find Full Text PDF

In Morocco no data has been published on canine exposure to Anaplasma spp., Borrrelia burgdorferi, and Ehrlichia spp., and only one report is available on the occurrence of Dirofilaria immitis in dogs.

View Article and Find Full Text PDF

Anaplasma phagocytophilum is an emerging tick-borne zoonosis with extensive increased interest. Epidemiological data are available in several regions of the USA, Europe and Asia in contrast to other parts of the world such as North Africa. Blood samples of 261 healthy individuals divided in two groups i.

View Article and Find Full Text PDF