Topological and functional analysis of nonalcoholic steatohepatitis through protein interaction mapping.

Aim: The corresponding proteins are important for network mapping since the interaction analysis can provide a new interpretation about disease underlying mechanisms as the aim of this study.

Backgroud: Nonalcoholic steatohepatitis (NASH) is one of the main causes of liver disease in the world. It has been known with many susceptible proteins that play essential role in its pathogenesis.

Introduction of inflammatory bowel disease biomarkers panel using protein-protein interaction (PPI) network analysis.

Aim: In the present study, a protein-protein interaction network construction is conducted for IBD.

Background: Inflammatory bowel diseases as serious chronic gastrointestinal disorders attracted many molecular investigations. Diverse molecular information is present for IBD.

Primary sclerosing cholangitis associated with elevated immunoglobulin-g4: a preliminary study.

Background. Immunoglobulin IgG4-associated cholangitis (IAC) disease is a systemic disease histologically characterized by extensive T lymphocytes and IgG4 positive plasma cell infiltration in various organs. Prevalence of IAC in PSC patients was reported to be between 7% and 11.

Clinicopathological significance of E-cadherin, β-catenin and p53 expression in gastric adenocarinoma.

Background: E-cadherin/catenin complexes exert a role in cell adhesion. β-catenin is a key player in Wnt signaling pathway in gastric cancer. P53 is a tumor suppressor gene which also regulates apoptosis.