Circular RNAs as a new perspective in the diagnosis and mechanism of Leishmania infections.

Leishmaniasis is a neglected infectious disease that affects millions of people worldwide. Visceral leishmaniasis (VL) caused by Leishmania infantum and cutaneous leishmaniasis (CL) caused by L. major/ L.

Comparative effects of 8-week combined resistance exercise training and alternate-day calorie restriction on soluble epidermal growth factor receptor (sEGFR) and adipsin in obese men.

This study investigated the combined effects of resistance exercise training (RET) and alternate-day calorie restriction (ADCR) on body composition, insulin resistance (IR), insulin resistance-related biomarkers (adipokine adipsin and hepatokine soluble EFGR), and weight loss in obese men. The findings revealed that RET + ADCR induced the greatest reductions in body weight, body fat percentage, and waist-to-hip ratio (WHR) compared to RET and ADCR alone ( < 0.05).

Meteorin-like protein (Metrnl): A metabolic syndrome biomarker and an exercise mediator.

Metrnl is a secreted protein able to activate different intracellular signaling pathways in adipocytes, macrophages, myocytes and cardiomyocytes with physiological effects of the browning of white adipose tissue (BWT), insulin sensitivity, inflammation inhibition, skeletal muscle regeneration and heart protection. Shown to be regulated by obesity, diabetes, caloric restriction, weight loss and heart diseases, Metrnl is definitely involved in metabolic turbulences, and may play roles in metabolic syndrome (MetS). However, due to the conflicting data yielded, Metrnl is still far from clinical application as a diagnostic and/or a therapeutic agent or even a therapeutic target in MetS-related diseases such as type 2 diabetes (T2D) and obesity.

Effectiveness of Care for Child Development Program on the Sensitivity and Responsiveness Skills of Mothers.

Objectives: The present study was done to analyze the impact of the "care for child development" program on the sensitivity and responsiveness skills among mothers of children at risk of developmental delay.

Materials & Methods: This study was a quasi-experimental research with a pretest-posttest design and experimental and control groups. The statistical population included all mothers with children at risk of developmental delay in Tabriz.

Myokine-mediated exercise effects: the role of myokine meteorin-like hormone (Metrnl).

Meterorin-like hormone (Metrnl), as a novel secreted factor, has been shown to be involved in physiological and pathophysiological processes. The behaviour of Metrnl in metabolic conditions like type 2 diabetes is conflicting. Metrnl-mediated (treatment with Metrnl) auto/paracrine actions in skeletal muscle are glucose uptake, fat oxidation and muscle regeneration.

Five-factor model trait profiles of narcissistic grandiosity and narcissistic vulnerability in Iranian university students.

This study examined the relationship between pathological narcissism, narcissistic grandiosity, narcissistic vulnerability and the five-factor model of personality. Participants consisted of 290 undergraduate students from four universities in three different cities in Iran, recruited by available sampling, Instruments, including, Pathological Narcissism Inventory (PNI) and the NEO Five-Factor Inventory (NEO-FFI) were also completed for the participants. Hierarchical regression analysis showed that narcissistic grandiosity was positively associated with extraversion and openness, while narcissistic vulnerability and overall pathological narcissism were positively associated with neuroticism and negatively related to agreeableness and openness (only for narcissistic vulnerability).

Psychometric properties of the behavior rating inventory of executive function, second edition (BRIEF2) in a sample of children with ADHD in Iran.

This study investigated the psychometric properties of a Persian translation of the Behavior Rating Inventory of Executive Function(BRIEF2) in 253 children with ADHD in Iran (137 boys, 116 girls)ages 8 to 12 years old ( = 10.04;  = 1.42).

Downhill running exercise increases circulating level of myokine meteorin-like hormone in humans.

Background: Meteorin-like hormone (Metrnl) is a myokine with immunoregulatory traits. This study aimed at evaluating the response of the plasma levels of Metrnl to a downhill running exercise (DHRE) in humans.

Methods: Twenty active male college students (aged: 22±1.

Association of Meteorin-Like Hormone with insulin resistance and body composition in healthy Iranian adults.

Background And Aims: Sedentary behavior and/or physical inactivity are modifiable risk factors for noncommunicable diseases. Myokines are one of the mediators of physical activity health benefits. Relationship between regular physical activity (RPA) and baseline plasma Meteorin-Like Hormone (Metrnl) has not been explored in human.

The effects of circuit resistance training on plasma progranulin level, insulin resistance and body composition in obese men.

Background Progranulin (PGRN) is implicated in obesity and insulin resistance (IR). The aim of this study was to evaluate the effects of 8 weeks of circuit resistance training (CRT) on plasma PGRN, IR and body composition in obese men. Materials and methods Twenty-eight healthy obese men [age: 36 ± 7.

High intensity intermittent training induces anti-inflammatory cytokine responses and improves body composition in overweight adolescent boys.

Background Anti-inflammatory cytokines, interleukin-4 (IL-4) and interleukin-13 (IL-13) modulate systemic energy metabolism through modifying body composition parameters. Hence, this study aimed at overweight adolescent boys to explore the effect of high intensity intermittent training (HIIT) on these anti-inflammatory cytokines and body composition parameters. Materials and methods Twenty overweight adolescent boys [aged: 18.

Comparing Behavioral-Emotional Difficulties in Siblings of Children with and without Sensory Impairments.

Background: Siblings of children with disabilities are the most likely family members to be affected by the child's disability due to the long-lasting nature of relationships between siblings compared to those of other family members. The aim of the present study was to compare the emotional-behavioral difficulties (EBD) in siblings of children with and without Sensory Impairments (SI).

Methods: The statistical population of this causal-comparative research included all siblings of children with and without SI in Shiraz, southern Iran in 2016.

Prevalence of IgG and IgM anti-Toxoplasma gondii Antibodies in Blood Donors at Urmia Blood Transfusion Organization, Iran.

Objective: The importance of toxoplasmosis lies in its global spread, opportunistic nature, and causative role in abortion or irreparable adverse effects on infants of infected pregnant women. Toxoplasma gondii has different transmission routes to humans, including blood transfusion. The objective of the present study was to evaluate the prevalence of IgG and IgM antibodies specific for T.

A Comparative Study of Group Behavioral Activation and Cognitive Therapy in Reducing Subsyndromal Anxiety and Depressive Symptoms.

Objective: This study compared the effectiveness of two group treatments, behavioral activation (BA) and cognitive therapy (CT), in reducing subsyndromal anxiety and depressive symptoms in a sample of Iranian university students.

Method: Twenty-seven Iranian university students who scored 18 or higher on the depression subscale and 16 or higher on the anxiety subscale of the Depression, Anxiety, and Stress Scale (DASS-42) were randomly assigned into treatment groups. One group received 8 sessions of BA (n = 14), and the other received 8 sessions of group CT (n = 13).

Acute effects of ginger extract on biochemical and functional symptoms of delayed onset muscle soreness.

Background: Inflammation and pain induced by delayed onset muscle soreness (DOMS) as a result of eccentric exercise (EE) or unaccustomed activity cause some difficulties in exercise for athletes. The purpose of this study was to survey the effect of ginger extract on biochemical and functional symptom of delayed onset muscle soreness.

Methods: In a quasi-experimental study, 36 healthy female subjects, who were recruited by intra dormitory calls, randomly divided into 3 groups, including: ginger intake 1 hour before exercise (GIBE), ginger intake immediately after exercise (GIAE) and placebo group (PL).

Effects of aerobic and anaerobic training programs together with omega-3 supplement on interleukin-17 and CRP plasma levels in male mice.

Background: Herein, we studied the effects of two different exercise protocols on IL-17 and CRP plasma levels along with the anti-inflammatory effects of fish oil. The purpose of the present study was to investigate the effect of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) consumption along with two different types of physical activities on IL-17 and CRP plasma levels in trained male mice.

Methods: A total of 130 adult male mice of Syrian race with the age of 2 months and the weight of 35±1 grams were selected.

Effect of aerobic exercise and fish oil supplements on plasma levels of inflammatory indexes in mice.

Background: Exercise has positive and negative effects on immune system. Herein, we would like to investigate the effects of incremental aerobic training and fish oil supplementation on the plasma levels of CRP, CPK and IL-17 in trained mice. One of the major roles of immune system is to produce soluble or cellular components that provide the immunity against inflammatory agent.

Parental self-confidence, parenting styles, and corporal punishment in families of ADHD children in Iran.

Objective: This study examines the relationship between parental self-confidence, warmth, and involvement, and corporal punishment in families of children with attention deficit/hyperactivity disorder (ADHD).

Method: The diagnosis of ADHD was established through clinical interviews with the parents, children, and teachers, according the criteria in DSM-IV-TR. This diagnosis was also established by having the parents complete the Conners' Parent Rating Scale, and the teachers complete the Conners' Teacher Rating Scale.