Antimicrobial Feature of Nanoparticles in the Antibiotic Resistance Era: From Mechanism to Application.

The growth of nanoscale sciences enables us to define and design new methods and materials for a better life. Health and disease prevention are the main issues in the human lifespan. Some nanoparticles (NPs) have antimicrobial properties that make them useful in many applications.

A turn-off fluorimetric -aptasensor for early detection of apoptosis inside the cells.

To detect cytochrome c (Cyt c) as an important biomarker of apoptosis inside the cells, a simple, label-free, fluorometric detection method has been presented. For this purpose, an aptamer/gold nanocluster probe (Aptamer@AuNCs) was produced which could specifically bind to Cyt c leading to fluorescence quenching of AuNCs. The developed aptasensor showed two linear ranges of 1-80 μM and 100-1000 μM and a detection limit of 0.