[Sleep architecture in schizophrenia patients].

Objective: Sleep disorders are a common and important part of schizophrenia's clinical Picture; however, the number of polysomnography-based studies of schizophrenia is limited and there is a lack of consensus regarding a specific sleep pattern in schizophrenia patients. As such, the aim of the present study was to investigate the sleep architecture in non-medicated schizophrenia patients.

Method: The study included 13 adult male inpatients with schizophrenia, undifferentiated type, (based on DSM-IV-TR criteria) and an age- and sex-matched group of normal controls.

Patient adherence and efficacy of quetiapine treatment in schizophrenia: results of a multicentre, naturalistic 6-month follow-up study.

The aim of the study was to evaluate the adherence and efficacy of quetiapine treatment in a 6-month, multicentre, noninterventional naturalistic design. Overall, 710 schizophrenia patients using quetiapine or who had switched to quetiapine were included. The continuation rate for quetiapine treatment during 6-month follow-up period was 69%.

Polysomnography in patients with post-traumatic stress disorder.

Aims: The purpose of the present study was to investigate sleep structure in post-traumatic stress disorder (PTSD) patients with and without any psychiatric comorbidities. The relationship between sleep variables and measurements of clinical symptom severity were also investigated.

Methods: Sleep patterns of 24 non-medicated male PTSD patients and 16 age- and sex-matched normal controls were investigated on polysomnography on two consecutive nights.

Effectiveness of psychoeducation intervention on post-traumatic stress disorder and coping styles of earthquake survivors.

Aims And Objectives: The aim of the study was to examine the effectiveness of a psychoeducation intervention based on Peplau's approach, including problem-solving compared with intervention with medication on post-traumatic stress disorder (PTSD) symptoms and coping of earthquake survivors.

Background: Post-traumatic reactions and recovery are the result of complex interactions among biological, personal, cultural and environmental factors. Both psychosocial and psychopharmacological methods have been advised to treat PTSD.

Oscillatory responses representing differential auditory processing in sleep.

The goal of the study was to investigate the contribution of the delta and theta responses to the peaks on the event-related potential waveform and specifically to find the possible cognitive correlates of these oscillatory responses in rapid eye movements (REM) sleep and Stage 2 (spindle sleep), Stage 3 (light sleep) and Stage 4 (deep sleep; slow wave sleep) of non-REM sleep. Data on overnight sleep was acquired from 12 healthy, young adult, volunteer males; those on awake stage were obtained from 19 matched males. Brain activity was obtained in response to auditory stimuli (2000 Hz deviant and 1000 Hz standard stimuli: 65 dB, 10 ms r/f time, 50 ms duration) under passive oddball paradigm in sleep, active and passive oddball (OB-a, OB-p, respectively) paradigms in wakefulness.

In restless legs syndrome, during changes in vigilance, the forced EEG shifts from alpha activity to delta or high alpha may lead to the altered states of dopamine receptor function and the symptoms.

RLS cases may carry a genetic vulnerability called EEG alpha activity gate dyscontrols which appear during changes in vigilance and generally during sleep. It is triggered by forced EEG shifts either from alpha activity to delta or high alpha. Expressions of alpha activity gate dyscontrols may have a gate effect that trigger a second vulnerability-dopamine receptor specific individual sensitivity (DRSIS) and this leads to a deficiency in dopamine transmissions at diencephalospinal dopamine system (DSDS).

Treatment of compulsive sexual behaviour with clomipramine and valproic acid.

The concepts of compulsive sexual behaviour or sexual addiction and treatment of the disorder have been argued over by many investigators. From a scientific point of view, both concepts are still not well established in psychiatric nomenclature. On the other hand, authors point out that compulsive sexual behaviour, obsessive-compulsive disorder and substance addiction show similarities in symptomatology and response to treatment.

Prevalence of insomnia symptoms: results from an urban district in Ankara, Turkey 1.

Objective. Characteristics of insomnia symptoms in Turkey are not well established. The goal of this study was to determine the prevalence of insomnia and related symptoms in an urban district of Turkey.

Evaluation of periodic leg movements and associated transcranial magnetic stimulation parameters in restless legs syndrome.

Restless legs syndrome (RLS), a sensorimotor disorder characterized by unpleasant sensations commonly localized in the legs, is frequently associated with periodic limb movements (PLMs) during sleep. We investigated the role of transcranial magnetic stimulation (TMS) and cortical silent period (CSP) duration as diagnostic and monitoring tools in 20 patients with primary RLS before and after 1 month of treatment and also studied 15 normal age- and gender-matched subjects. Polysomnographic assessment was undertaken and the PLM index determined in 17 of the 20 patients.