Osteoprotegerin as a marker of cardiovascular risk in children and adolescents with type 1 diabetes.

Background: Elevated osteoprotegerin (OPG) levels have been reported in patients with diabetes complications. We investigated whether plasma OPG levels can be used as a marker of cardiovascular risk in children and adolescents with type 1 diabetes (T1D).

Methods: Plasma blood samples were obtained from 243 subjects (143 children and adolescents with T1D and 100 healthy controls).