Primary heavy silicone oil usage in inferior rhegmatogenous retinal detachment.

Purpose: To evaluate the efficacy and complications of heavy silicone oil (Densiron 68) in primary inferiorly located retinal detachment.

Methods: Sixty-seven eyes of patients aged 24-79 years with inferior primary rhegmatogenous retinal detachment with/without proliferative vitreoretinopathy grades C and lower were included in the study. The mean duration of the Densiron endotamponade was 87 days (range, 60-180 days), with a mean follow-up after removal of 110 +/- 41 days.

Posterior-segment surgeries with a two-port modified multiport illumination system.

Purpose: The purpose of this study was to evaluate the safety and efficacy of a modified two-port multiport illumination system (MIS) in different vitreoretinal surgeries.

Patients And Methods: Sixty-one patients had undergone pars plana vitrectomy for complications of retinal diseases with the modified MIS. Only two-port pars plana vitrectomy was performed with the MIS.

Surgical excision, cryotherapy, autolimbal transplantation and mitomycin-C in treatment of conjunctival-corneal intraepithelial neoplasia.

Purpose: To report surgical excision, cryotherapy, autologous conjunctival-limbal transplantation and topical mitomycin C (MMC) in the patient with extensive conjunctival-corneal intraepithelial neoplasia.

Methods: Case report and literature review.

Results: A 75-year-old woman was referred to our department with the diagnosis of conjunctival-corneal neoplasia.

Inhibition of experimental proliferative vitreoretinopathy with protein kinase C inhibitor (chelerythrine chloride) and melatonin.

Purpose: To investigate whether a protein kinase C (PKC) inhibitor and melatonin prevent proliferative vitreoretinopathy (PVR).

Methods: Twenty pigmented rabbits were used in this study. All rabbits except controls received an intravitreal injection of 0.

Intravitreal cortisone injection for refractory diffuse diabetic macular edema.

Purpose: The purpose of this study was to evaluate the safety and efficacy of intravitreal triamcinolone acetonide injection in patients with diffuse diabetic macular edema. We also compared the effect of intravitreal triamcinolone with macular grid laser photocoagulation in macular edema.

Patients And Methods: Thirty patients with diabetic diffuse macular edema unresponsive to grid laser photocoagulation for at least 4 months received 0.

Adrenomedullin and leptin levels in diabetic retinopathy and retinal diseases.

Purpose: Proliferative and vascular retinal diseases are important cause of irreversible blindness. Consistent features of these diseases are endothelial dysfunction and angiogenesis. Adrenomedullin (ADM) is a multifunctional vasorelaxant peptide.

Use of caffeic acid phenethyl ester and cortisone may prevent proliferative vitreoretinopathy.

Purpose: To investigate whether caffeic acid phenethyl ester (CAPE) and cortisone prevent proliferative vitreoretinopathy (PVR).

Methods: Twenty pigmented rabbits were used in this study. All rabbits except controls received an intravitreal injection of 0.

Urinary nitric oxide levels are increased and correlated with plasma concentrations in patients with Behçet's disease: is it a new urinary activity marker?

Nitric oxide (NO) is a free radical and serves many functions within the kidney. Excess NO causes glomerular injury. Behçet's disease (BD) is a systemic immunoinflammatory vasculitis, affecting every organ in the body including the kidneys (subclinic glomerulonephritis).

Nitric oxide and lipid peroxidation are increased and associated with decreased antioxidant enzyme activities in patients with age-related macular degeneration.

Background: Nitric oxide (NO), hydroxyl radical (OH*), superoxide anion (O2-) and hydrogen peroxide (H2O2) are free-radicals released in oxidative stress. Superoxide dismutase (SOD), glutathione peroxidase (GSHPx) and catalase (CAT) are antioxidant enzymes, mediating defense against oxidative stress. Excess NO and/or defective antioxidants cause lipid peroxidation, cellular dysfunction and death.

Comparison of secondary implantation of flexible open-loop anterior chamber and scleral-fixated posterior chamber intraocular lenses.

Purpose: To analyze and compare the outcomes and complication rates of secondary implantation of flexible, open-loop, anterior chamber intraocular lenses (AC IOLs) and single-piece, scleral-fixated, posterior chamber IOLs (PC IOLs).

Setting: Departments of Ophthalmology, Gaziantep University Medical Faculty, Research Hospital, Gaziantep, and Inönü University Medical Faculty, Research Hospital, Malatya, Turkey.

Methods: This study comprised 124 eyes of 113 aphakic patients (61 men, 52 women) with insufficient capsule support who had secondary IOL implantation from January 1997 to June 2001.

Lenticular astigmatism in tilted disc syndrome.

Purpose: To evaluate whether an abnormal optic disc shape in patients with tilted disc syndrome (TDS) is associated with an abnormal configuration of the crystalline lens measured as lenticular astigmatism.

Setting: Department of Ophthalmology, Inönü University Medical Faculty, Turgut Ozal Medical Center, Malatya, Turkey.

Methods: This cross-sectional masked case-control study comprised 32 eyes of 32 patients with established TDS (13 men, 19 women; mean age 21.

Use of caffeic acid phenethyl ester to prevent sodium-selenite-induced cataract in rat eyes.

Purpose: To investigate whether caffeic acid phenethyl ester (CAPE) prevents sodium-selenite-induced cataract.

Setting: Department of Ophthalmology and Biochemistry, Inonu University Medical Faculty, Turgut Ozal Medical Center, Research Hospital, Malatya, Turkey.

Methods: Sixty Sprague-Dawley rat litters were randomized into 3 groups.

Urinary adrenomedullin levels are increased and correlated with plasma concentrations in patients with Behçet's syndrome.

Background: The objective was to measure urinary adrenomedullin (AM) levels in patients with active or inactive Behçet's syndrome and compare them to levels in healthy control subjects.

Methods: Forty-five consecutive patients with Behçet's syndrome (20 men and 25 women with a mean age of 37.7 +/- 10.

Aqueous humor adrenomedullin levels differ in patients with different types of glaucoma.

Purpose: Adrenomedullin is a multifunctional 52 amino acid large peptide. Recent studies have reported that it is expressed in the iris-ciliary body in the eye and that it decreases intraocular pressure (IOP) by increasing outflow facility via specific adrenomedullin receptors, suggesting a role for this peptide in controlling IOP. In the present study, we aimed to explore clinically the possible involvement of adrenomedullin in the pathophysiology of glaucoma.

Serum levels of TNF-alpha, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet's disease.

Aim: Behçet's disease (BD) is asystemic immunoinflammatory disorder and the aetiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case-control study is to investigate serum pro-inflammatory cytokine tumour necrosis factor (TNF)-alpha, interleukin-1beta (IL-1beta), soluble IL-2 receptor (sIL-2R), IL-6, and chemokine IL-8 levels in patients with BD.