What are family caregivers' experiences of coordinating end-of-life care at home? A narrative review.

Objectives: People with life-limiting diseases, who are no longer receiving active or curable treatment, often state their preferred place of care and death as the home. This requires coordinating a multidisciplinary approach, using available health and social care services to synchronize care. Family caregivers are key to enabling home-based end-of-life support; however, the 2 elements that facilitate success - coordination and family caregiver - are not necessarily associated as being intertwined or one and the same.

Single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine in mechanically ventilated ICU patients: A study protocol of a feasibility randomized controlled trial with an embedded qualitative study.

Background: Endotracheal suction catheters are often used multiple times during endotracheal suctioning procedures in resource-limited intensive care units (ICU). The impact of this practice on mechanically ventilated patients' outcomes remains unclear.

Aim: The aim of this feasibility randomized controlled trial (fRCT) is to assess the feasibility and acceptability of single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine in mechanically ventilated ICU patients.

An exploration of sharps injuries within healthcare students at a UK university.

Background: There is evidence available worldwide that nursing, medical and dental students sustain sharps injuries during their programmes of study. However, there is lack of evidence and research relating to the many students of other healthcare professions who may encounter sharps instruments.

Aim/objective: The aim of the study was to identify the extent, type and impact of sharps injuries sustained by pre-registration healthcare students.

A narrative review of patients' lived experience of having a pressure injury.

Aim: To explore patients' experiences of living with pressure injuries.

Design: A qualitative narrative review and thematic synthesis of qualitative research studies.

Data Sources: Six electronic databases were searched: Medline, CINAHL, Scopus, Web of Science, Embase, and Google Scholar (for grey literature).

Sharps injuries within the healthcare student population: a narrative review.

Background: Studies have reported evidence on sharps injuries among nursing, medical and dental students but little is known about the amount, type and causes of sharps injuries affecting other healthcare students.

Aim: The aim of the narrative review was to identify the extent, type and causes of sharps injuries sustained by healthcare students, especially those not in those fields.

Method: Eight databases were searched using keywords to identify studies published between 1980 and March 2023.

Origins, characteristics and destination of nursing students in South West England.

Background: Worldwide there are concerns about the supply of nurses into health systems. Understanding and balancing the supply of and demand for healthcare professionals is crucial to efficient healthcare delivery, yet there is relatively little research that examines in detail where nursing students come from and where they go after qualification.

Objectives: To investigate the demographic characteristics of applicants to nursing and midwifery programmes in England, those that are enrolled, attrition during study, and their career intentions on graduation.

Exploring the psychological effects of sharps injuries sustained by healthcare workers.

Much of the research into sharps injuries sustained by healthcare workers focuses on prevalence and incidence and to a lesser extent the financial implications of such injuries. An under-researched area is the psychological effects of such injuries. This article reports the findings of a narrative literature review that aimed to synthesise the evidence on this subject.

The psychological impact of sharps injuries sustained by medical students.

Much is known and reported about sharps injuries among healthcare workers, but there has been a lack of published evidence regarding the psychological impact of sharps injuries among medical students. The purpose of this narrative review was to discover the psychological impact of sharps injuries within the medical student population. Medical, health and psychology databases were searched for studies written in the English language and published between 1980 and 2021.

Investigating the incidence and type of sharps injuries within the nursing student population in the UK.

Aims: To identify the incidence and type of sharps injuries within a UK nursing student population.

Background: Evidence suggests that nursing students sustain sharps injuries across the world, but there is a lack of data from the UK. Design: Questionnaire survey.

The experience and psychological impact of a sharps injury on a nursing student population in the UK.

Aims: The aims of this study were to explore the experience and psychological impact of sustaining a sharps injury within a nursing student population in the UK. Design: A qualitative approach was taken, using two methods to gather data, namely a Twitter chat and interviews.

Methods: A Twitter chat was orchestrated to investigate the experiences of sharps injury with nursing students and registered nurses nationwide (=71).

Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis.

Background: Sequencing studies have pointed to the involvement in schizophrenia of rare coding variants in neuronally expressed genes, including activity-regulated cytoskeleton-associated protein (ARC) and N-methyl-D-aspartate receptor (NMDAR) complexes; however, larger samples are required to reveal novel genes and specific biological mechanisms.

Methods: We sequenced 187 genes, selected for prior evidence of association with schizophrenia, in a new dataset of 5207 cases and 4991 controls. Included among these genes were members of ARC and NMDAR postsynaptic protein complexes, as well as voltage-gated sodium and calcium channels.

The impact of sharps injuries on student nurses: a systematic review.

Aims And Objectives: The purpose of this review was to discover the impact of sharps injuries in the student nurse population.

Background: Much is known and reported about sharps injuries in registered nurses, but there has been a lack of published evidence regarding sharps injuries within the student nurse population.

Method: A systematic review of nursing, health and psychology databases was conducted.

Undetectable pregnancy-associated plasma protein-A in antenatal serum Down's syndrome screening: a case of assay interference.

Serum pregnancy-associated plasma protein-A (PAPP-A) is measured in Down's syndrome screening, routinely offered to women in pregnancy. We present the case of an undetectable pregnancy-associated plasma protein-A concentration on the PerkinElmer AutoDELFIA system where immunoassay interference was suspected. Investigations performed, including dilution and recovery studies and antibody-blocking tube incubations, all yielded serum pregnancy-associated plasma protein-A concentrations of <25 mU/L.

Assessing the risk of post-operative nausea and vomiting.

Post-operative nausea and vomiting (PONV) is a common complication for many surgical patients, causing anxiety and distress. Evidence suggests that nursing practice in this area is inconsistent and that nurses' knowledge needs to improve, to promote better patient outcomes. This article provides a review of the incidence of PONV, associated complications and risk factors.

Needlestick and sharps injuries in the nursing student population.

Needlestick injuries (NSIs) and sharps injuries are a potential source of harm. Such injuries can cause considerable distress and have an economic effect on both the person who is injured and the healthcare organisation. Although data regarding trained nurses are more plentiful, there is a dearth of published information and research on the incidence and causes of NSIs and sharps injuries in the nursing student population, especially in the UK.

The management of lipohypertrophy in diabetes care.

Lipohypertrophy has been a recognized complication of insulin therapy for many years, yet research shows that its prevalence in insulin-injecting patients with diabetes remains high. The problem for the patient is that the injection of insulin into a site of lipohypertrophy, although painless, may lead to erratic absorption of the insulin, with the potential for poor glycaemic control and unpredictable hypoglycaemia. Despite the important implications of this for diabetes control in insulin-injecting patients, there is a dearth of information and completed research into the condition.