An effective percutaneous transvenous mitral commissurotomy (PTMC) and aortic valvotomy (PTAV) was performed upon a 61-year-old male patient suffered from acute left heart failure due to combined valvular disease (mitral and aortic stenosis) and had complicated with acute renal failure following low cardiac output. Hemodynamic study being examined through Swan-Ganz catheter and echocardiography after PTMC and PTAV showed marked releaf from these two valvular stenosis. We consider that although this new treatment can't exceed surgical commissurotomy in an effect, it can be applied to those who are thought to be riskfull for the surgical intervention because of its inherent characteristics being simple and less invasive.
View Article and Find Full Text PDFA case report is presented of a 73-year-old male who was seen with fever, jaundice, abdominal pain and central nervous system depression. He failed to respond to intensive antibiotic therapy, and subsequently acute obstructive suppurative cholangitis fully developed. Upon laparotomy, the patient's gallbladder was found to be enlarged with the bile from the gallbladder and bile duct itself containing a high pus content.
View Article and Find Full Text PDFThe pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral administration of 10 to 100 mg of CV-4151, peak plasma levels of 1-6 micrograms/mL were reached in a dose-dependent manner within 1 hour.
View Article and Find Full Text PDFNihon Geka Gakkai Zasshi
March 1988
The authors, having experienced 17 cases of subclavian arterial obstruction at its origin in Montpellier, France and in Japan, performed direct anastomosis between the divided end of the proximal subclavian artery and the ipsilateral common carotid artery (transposition technique) in 12 cases. Our series of 17 patients ranging in age from 30 to 73 years who were evaluated for variety of symptoms: 8 had subclavian steal syndrome; 12 had claudication of upper extremity; 1 had visual disturbance; 3 had vertigo; and 1 had ear throbbing. Twelve patients were treated surgically with division of the proximal subclavian artery and its anastomosis to the common carotid artery by means of supraclavicular cervicotomy.
View Article and Find Full Text PDFWe examined the effects of a new inotrope, OPC-8212 (OPC: 2(1H)-quinolinone), on coronary sinus flow (CSF), myocardial oxygen consumption, myocardial lactate extraction ratio (LER), cardiac index (CI) and pulmonary arterial diastolic pressure (PADP) in eleven patients with prior myocardial infarction. Measurements were taken before (control) and 8 hours after administration of OPC (480 mg, p.o.
View Article and Find Full Text PDFThe present study was performed to measure and calculate the mechanical force of percutaneous balloon valvotomy (PBV) for mitral valvular stenosis, using an equation pertaining to the mechanical force of the balloon needed to dilate the stenotic mitral valve. In case 1, the diameter of the mitral valve was enlarged by PBV from 1.43 cm to 2.
View Article and Find Full Text PDFHeart Vessels
September 1988
Transvenous mitral commissurotomy (TMC) was conducted with transesophageal echocardiography (TEE) in two patients with mitral stenosis. It was possible to see clearly not only the intracardiac structures to be examined by TMC, such as the right and left atria, interatrial septum, and mitral valve, but also the instruments used in TMC, such as the catheter, guidewire, and balloon. It was possible to determine the positional relation between the intracardiac structures and instruments.
View Article and Find Full Text PDFTo develop ultrasonic cardiac tissue characterization, serial changes in intensity of backscattered ultrasound from the normal and infarcted myocardium were studied in vitro, with frequency-domain analysis. As an index of backscattered signal intensity, quantitative integrated backscatter [(10 X log-S2/S1)] (dB), S1 and S2 = areas of power spectra of digitized (sample rate = 100 MHz, 8 bits) ultrasonic signals from a perfect reflector and good specimens) were calculated for 60 regions of the myocardium (N = 20, MI = 40) excised from 10 dogs 3 days, 1, 2, and 4 weeks after coronary artery ligation in 2, 3, 3, and 2 dogs, respectively. The myocardial specimens and a stainless steel reflector were mounted at the focal distance of a newly-developed wide-band transducer having a center frequency of 4.
View Article and Find Full Text PDFExperimental achalasia dogs produced with Deloyer's method showed higher resting pressure at the gastroesophageal junction and the increase in LES pressure in response to tetragastrin and cholecystokinin. Dose-response curve of the LES to each dose of tetragastrin in achalasia dog shifted to the left. Resting LES pressure in 11 patients with achalasia was 42.
View Article and Find Full Text PDFHiroshima J Med Sci
June 1985
For the echocardiographic assessment of intramyocardial blood flow distribution by intravenous contrast echocardiographic technique, we measured the echo intensity of a point (phi 6 mm) in the interventricular septum using a lightmeter in end-diastole before and after the intravenous injection of various dosages of ether or hydrogen peroxide in one open-chest and four closed-chest dogs. Before the injection of contrast media, the echo intensity of the myocardium varied within a range of 6.1 +/- 4.
View Article and Find Full Text PDFTrans Am Soc Artif Intern Organs
June 1985
Trans Am Soc Artif Intern Organs
June 1985