Assessment of the Predictive Factors Influencing the Diagnosis and Severity of Villous Atrophy in Patients with Celiac Disease and Iron Deficiency Anemia Referred for Diagnostic Endoscopy in Basrah, Iraq.

The classic celiac disease (CD) presentation in individuals with iron deficiency anemia (IDA) has been changed given the large percentage of subtle or asymptomatic cases. The study objective was to assess the predictive factors influencing the diagnosis and severity of villous atrophy in individuals with CD and IDA referred for a diagnostic endoscopy. This was a retrospective observational, cross-sectional analysis of the medical records of 499 individuals with IDA in 2 centers in Basrah, Iraq, who referred for possible diagnosis of CD within 10 years (2006-2016).

A Giant Ureteral Inflammatory Myofibroblastic Tumor in a 4-Year-Old Child: A Case Report and Review of the Literature.

Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm of children and young adults. It consists of myofibroblastic cells of borderline malignancy admixed with inflammatory cells. According to the WHO classification, of tumors, it is a soft-tissue tumor with an intermediate malignant potential.

Duplication of the urethra in an adult male presenting with scrotal fistula: a rare case report.

Urethral duplication is a rare congenital abnormality with varied clinical manifestations; to this day, <300 cases were reported in the literature. It is affecting mainly males and is nearly always diagnosed in childhood or adolescence. It may be complete or incomplete, and the most widely accepted classification of the different types of urethral duplication was developed by Effman .

Right-sided varicocele thrombosis complicating an acute epididymo-orchitis: A case report and review of the literature.

Unilateral right-sided varicocele is a rare and warning condition that should hint at a serious retroperitoneal disease such as renal cell neoplasm. Furthermore, its thrombosis is such an unusual entity that only a few cases have been described. We review the literature and report, to our knowledge, the second case of acute scrotal pain caused by unilateral right-sided varicocele thrombosis complicating an ipsilateral epididymo-orchitis, with no underlying coagulopathy or abdominal neoplasm, to illustrate the clinical, morphologic and therapeutic features of this entity.

Synergistic effect and VEGF/HSP70-hom haplotype analysis: relationship to prostate cancer risk and clinical outcome.

Prostate cancer (PCa) is a complex disorder resulting from the combined effects of multiple environmental and genetic factors. Our previous single-locus analysis showed that VEGF and HSP70-hom polymorphisms were significantly associated with PCa susceptibility and prognosis. Both genes encoding these proteins were located on chromosome 6p21, and combining the neighboring single nucleotide polymorphisms (SNPs) into haplotypes may increase the association with the disease.

Clinical findings and prevalence of helicobacter pylori in patients with gastritis B in Al-basrah governorate.

Objectives: To detect the prevalence of H. pylori in patients with gastritis B.

Methods: This study involved 58 patients (group A) with gastritis B attending the Al-Sadder teaching hospital from January to November 2008.

[Prostate cancer: comparative study of stage T1a and stage T1b].

Objective: To compare the epidemiological profiles and histoprognostic factors of two groups of prostate cancer: T1a versus T1b.

Materials And Methods: Between January 1996 and December 2005, 1359 patients were operated for benign prostatic hyperplasia (BPH) in our urology department. All patients had a PSA less than 4 ng/ml, an adenomatous prostate on digital rectal examination with a homogeneous appearance on prostatic ultrasonography.

[To analyse diagnosis, management and prognosis of florid cystitis glandularis (pseudoneoplastic entity)].

Purpose: To analyse diagnosis, management and prognosis of florid cystitis glandularis (pseudoneplastic entity).

Patients And Methods: A retrospective study of 6 consecutive patients with florid cystitis glandularis seen at the department of Urology of Monastir (Tunisia) from January 1996 to July 2006. All patients underwent ultrasonography, and cystoscopy.

Combined effects of the angiogenic genes polymorphisms on prostate cancer susceptibility and aggressiveness.

The single-gene approaches in association studies of polygenic diseases are likely to provide limited value in predicting risk. The combined analysis of genetic variants that interact in the same pathway may amplify the effects of individual polymorphisms and enhance the predictive power. To evaluate higher order gene-gene interaction, we have examined the contribution of four angiogenic gene polymorphisms (VEGF-1154G/A; VEGF-634G/C; MMP9-1562C/T and TSP1-8831A/G) in combination to the risk of prostate cancer.

Association of HSP70-hom genetic variant with prostate cancer risk.

Because of the importance of androgens to prostate cancer (PCa) development, several candidate genes along androgen pathway have been under intensive study. Given the role of the molecular chaperone HSP70 in the regulation of the androgen receptor (AR) transactivation function, we first chose to explore the association between the HSP70-hom functional genetic variant (+2437 T > C) and prostate cancer risk by genotyping DNA samples from 101 unselected PCa patients and 105 healthy men. There was a trend towards lower frequency of TC and CC genotypes among patients when compared with healthy controls, however the difference did not reach the statistical significance (TC genotype: OR = 0.

TSP1 and MMP9 genetic variants in sporadic prostate cancer.

Angiogenesis plays an important role in the initiation and progression of many malignancies including prostate cancer (PCa). Therefore, genes implicated in angiogenic pathways could be susceptibility candidate genes for this malignancy. In this respect, we investigated the impact of functional genetic variants of TSP1 (N700S) and MMP9 (-1562 C/T) genes on the development and progression of PCa.

Association of VEGF genetic polymorphisms with prostate carcinoma risk and clinical outcome.

Objectives: Vascular endothelial growth factor (VEGF) is a potent stimulus of angiogenesis that has an important role in many human malignancies including prostate carcinoma (PCa). We evaluated the role of the functional VEGF polymorphisms as genetic markers for PCa susceptibility and prognosis.

Methods: The study included 101 patients with PCa and [corrected] 100 age-matched healthy men.

[An unusual testicular tumour: splenogonadal fusion].

Splenogonadal fusion is a rare congenital anomaly that is often discovered at operation or autopsy. The diagnosis is difficult, but could be based on preoperative scintigraphy and frozen section histological examination to avoid useless orchidectomy. It is a benign lesion, which must be distinguished from testicular tumour.

[Florid glandular cystitis].

Introduction: Florid glandular cystitis is a rare benign bladder tumour, which can simulate a malignant lesion.

Material And Methods: Over a period of fifteen years, we have observed one case of recurrent florid glandular cystitis.

Results: This 48-year-old patient presented with terminal haematuria and right low back pain with a history of endoscopic resection of a bladder tumour.

[Encrusted cystitis].

Encrusted cystitis is a chronic inflammation of the bladder mucosa associated with calcified deposits induced by numerous bacteria in an alkaline medium. Corynebacterium urealyticum or group D2 is most frequently incriminated. Encrusted cystitis is a rare disease with non-specific clinical features.

[Twin pregnancy after renal transplantation: first case reported in Tunisia].

Women with end-stage renal disease or on regular dialysis have low fertility. Renal transplantation restores not only normal renal and endocrine functions but also the reproductive function as well and this conception becomes possible. Pregnancy in transplanted women is at higher risk and necessitates a multidisciplinary follow up.

[Leiomyoma of the urinary bladder].

Benign mesenchymal tumors of the bladder are rare. Leiomyoma is the most common mesenchymal tumor of the bladder. We report a new case.