Publications by authors named "Halle Marie Patrice"
Article Synopsis
- People with chronic illnesses, like those on dialysis, often have a lower quality of life, especially in countries like Cameroon.
- A study showed that most patients (about 76%) had low health-related quality of life scores, which means they weren't feeling very well overall.
- Many patients also faced social challenges, like not being able to attend school or find jobs, and their relationships often suffered because of their health issues.
Background: In spite of the global decreasing mortality associated with HIV, adolescents living with HIV (ADLHIV) in sub-Saharan Africa still experience about 50% mortality rate. We sought to evaluate survival rates and determinants of mortality amongst ADLHIV receiving antiretroviral therapy (ART) in urban and rural settings.
Methods: A multi-centered, 10-year retrospective, cohort-study including ADLHIV on ART ≥ 6 months in the urban and rural settings of the Centre Region of Cameroon.
Background: End-stage kidney disease is an independent risk factor for stroke; however, the relationship between hemodialysis and stroke in Sub-Saharan Africa has not been established.
Objective: To evaluate the incidence, associated factors, and clinical outcome of stroke among patients undergoing maintenance hemodialysis in Cameroon.
Methods: A hospital-based retrospective study using data from the medical files of 1060 patients on maintenance hemodialysis (given twice a week) was conducted.
Background: Acute kidney injury (AKI) is an under-recognized disorder, which is associated with a high risk for mortality, development of chronic kidney disease (CKD).
Objective: We sought to describe and compare the causes and outcomes of AKI amongst adult patients in Douala general hospital (DGH) and Buea regional hospital (BRH).
Methods: A hospital-based retrospective cohort analytic study was carried from February to April 2021.
Introduction: prognosis of lupus nephritis in sub-Saharan Africa is poorly known. The purpose of this study is to describe the clinical profile and survival of patients with lupus nephritis treated in the Department of Nephrology.
Methods: we conducted a single-centre retrospective cohort study over a period of 5 years.
Rituximab (RTX), a chimeric monoclonal anti-CD20 antibody has become part of the standard therapy for patients with CD20-expressing B-cell lymphoma and rheumatoid arthritis. After encouraging results with open studies in systemic lupus erythematosus (SLE), RTX has not shown its effectiveness in randomized controlled trials. However, its efficacy has been validated in renal, hematological, and neuropsychiatric disorders.
View Article and Find Full Text PDFBackground: Chronic kidney disease (CKD) is a major health problem with growing prevalence in sub-Saharan Africa.
Aim: Assess the prevalence and determinants of CKD in Garoua and Figuil cities of the North region of Cameroon.
Methods: A cross-sectional survey was conducted from January to June 2018 in the two cities, using a multi-level cluster sampling.
Background: Hemodialysis medical staffs usually work in a stressful environment. In low resource countries, professional conditions are worse and can lead to burnout syndrome. The aim of this study was to determine the prevalence of burnout syndrome and its associated factors in hemodialysis health care workers in Cameroon.
View Article and Find Full Text PDF[Epidemiologic and clinical profile, 90 days survival of incident end stage renal patient in haemodialysis during SARS-CoV2 pandemic: Experience of the General Hospital of Douala].
Nephrol Ther
August 2021
Article Synopsis
- - The study explored the impact of COVID-19 on patients with end-stage renal disease beginning hemodialysis in Cameroon, focusing on their epidemiology, clinical profiles, and 90-day survival rates during the pandemic.
- - Researchers conducted a cohort study over six months, observing 57 new hemodialysis patients, with 49% testing positive for COVID-19; those infected showed higher instances of severe complications like pulmonary edema and uremic encephalopathy.
- - Findings indicated a 90-day survival rate of only 48%, highlighting lower survival among COVID-19 patients and those from low socioeconomic backgrounds, with the latter increasing mortality risk significantly.
Background: A relationship exists between birth weight (BW) and glomerular filtration rate (GFR) in postnatal kidney. Willing to fill a gap of knowledge in sub-Saharan Africa, we assessed the effect of BW on blood pressure (BP), proteinuria and GFR among Cameroonians children.
Methods: This was a cross-sectional hospital-based study from January to April 2018 at the Yaounde Gynaeco-Obstetric and Paediatric Hospital (YGOPH).
Background: Non-adherence (NA) to hemodialysis regimens is one of the contributors to the high morbidity and mortality observed in patients with end-stage kidney disease (ESKD). We aimed to determine the prevalence and predictors of NA to hemodialysis (HD) regimens among patients on maintenance HD in Cameroon.
Methods: A cross-sectional study in two HD centers in Cameroon was conducted from January to February 2016.
Background: Uricemia dramatically rises with the stage of chronic kidney disease (CKD) and correlates with its mortality. Hemodialysis (HD) being the most used treatment at the end stage in sub-Saharan Africa, we sought to evaluate its efficacy on the clearance of uric acid (UAc) when used alone and twice per week.
Methods: A cross-sectional study of all consenting patients with CKD stage 5 recruited at random during HD sessions in a reference Centre in Cameroon from January to April 2017.
Background: Little is known about the changes in disease makers and risk factors in patients with chronic kidney disease (CKD) under nephrological care in Africa. This study aimed to evaluate the baseline level of markers of CKD and their 12-month time-trend in newly referred patients in a tertiary hospital in Cameroon.
Methods: This was a retrospective cohort study including 420 patients referred for CKD between 2006 and 2012 to the nephrology unit of the Douala General Hospital in the littoral region of Cameroon.
Intradialytic hypotension (IDH), one of the most frequent acute complications of hemodialysis (HD), is associated with increased patient's morbidity and mortality. The aim of this study was to determine its prevalence and associated factors among patients on maintenance HD in Cameroon. This was a prospective longitudinal study carried out from June 20, to July 30, 2016 (5 weeks), including adult patients on HD >3 months at a tertiary hospital in Douala.
View Article and Find Full Text PDFEchocardiographic left atrial remodelling and determinants of left atrial size in the early phase of high blood pressure: a comparative cross-sectional study in Douala, Cameroon.
Cardiovasc J Afr
November 2020
Background: Left atrial remodelling (LAR) has been described in Western populations with chronic hypertension and is associated with a higher risk of adverse cardiovascular events. Although hypertension tends to occur earlier and is more severe in sub-Saharan Africa than in more developed nations, LAR and its associated factors in these African hypertensive subjects have been poorly elucidated.
Objectives: To assess left atrial structural remodelling in black hypertensive patients and determine factors associated with left atrial size.
Background: Chronic kidney disease (CKD) is one of the major complications of Human immune deficiency Virus (HIV) and a risk factor for poor outcome of these patients. We aimed to describe the profile and outcome of HIV positive patients with CKD in Douala general hospital in Cameroon.
Methods: HIV positive patients with CKD referred to the nephrologist from January 2007 to March 2013 were included.
Background: Late presentation (LP) of chronic kidney disease (CKD) patients to nephrologist is a serious problem worldwide with persistent high prevalence despite known benefits of early nephrology care.
Objective: Determine the prevalence and factors associated with LP of CKD patients to nephrologists in Cameroon.
Methods: A cross-sectional study from October 2015 to May 2016 at the nephrology units of the Douala General and Laquintinie hospitals, including all consenting incident CKD patients.
Introduction: Chronic kidney disease (CKD) is frequent amongst human immunodeficiency virus (HIV)-positive patients, and screening is not routinely performed in Sub-Saharan Africa due to resource constraints. We aimed to determine the prevalence of CKD and associated factors in HIV-infected patients in Cameroon.
Materials And Methods: A cross-sectional study in Northern Cameroon included HIV-positive patients who attended the HIV clinic.
Article Synopsis
- Increased aortic pulse wave velocity (PWV), a measure of arterial stiffness, is a predictor of cardiovascular events in chronic kidney disease (CKD) patients, and this study examined its patterns among Cameroonian patients.
- The study involved 150 CKD patients and found that PWV increased with age; non-dialyzed patients had higher PWV than those on hemodialysis.
- The research indicated that 61.3% of participants had a PWV indicative of subclinical aortic damage, and advanced age, mean arterial pressure, and tobacco use were linked to higher PWV levels; further research is needed to explore these findings.
Hepatitis C virus (HCV) infection one of the most common blood-borne infections is endemic in Cameroon and a serious problem in hemodialysis (HD). We aimed to determine the annual incidence and factors associated with seroconversion to hepatitis C positivity amongst patients on maintenance HD after an exposition of two years in a center with a high prevalence of hepatitis C (20.6%) and where no isolation policy is practiced.
View Article and Find Full Text PDFBackground: Chronic kidney disease (CKD) poses a substantial health burden in sub-Saharan Africa, with risk factors ranging from communicable to non-communicable diseases. Hyperuricemia has been recently identified as a factor of progression of CKD. Identifying factors associated with hyperuricemia in CKD patients would help determine interventions to reduce CKD mortality, particularly in resources limited countries.
View Article and Find Full Text PDFBackground: There are conflicting reports on the impact of HIV in the era of combined antiretroviral (c-ART) on survival of patient with ESKD. We aimed to compare the one-year survival of HIV positive patients to that of their HIV negative counterparts with ESKD on maintenance haemodialysis in Cameroon.
Methods: This was a retrospective cohort study conducted in the haemodialysis units of the Douala and Yaoundé General Hospitals.
Introduction: home blood pressure measurement (HBPM) is not entirely capable of replacing ambulatory blood pressure (BP) measurement (ABPM), but is superior to office blood pressure measurement (OBPM). Although availability, cost, energy and lack of training are potential limitations for a wide use of HBPM in Sub-Saharan Africa (SSA), the method may add value for assessing efficacy and compliance in specific populations. We assessed the agreement between HBPM and ABPM in chronic kidney disease (CKD) patients in Douala, Cameroon.
View Article and Find Full Text PDFBackground: Pediatric nephrology is challenging in developing countries and data on the burden of kidney disease in children is difficult to estimate due to absence of renal registries. We aimed to describe the epidemiology and outcomes of children with renal failure in Cameroon.
Methods: We retrospectively reviewed 103 medical records of children from 0 to 17 years with renal failure admitted in the Pediatric ward of the Douala General Hospital from 2004 to 2013.
Introduction: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created haemodialysis units in Cameroon: the Buea and Bamenda haemodialysis centres.
Methods: A cross sectional study: included were patients who had spent at least three months in haemodialysis.