Properties of Mitotic and Meiotic Recombination in the Tandemly-Repeated Gene Cluster in the Yeast .

In the yeast , the genes encoding the metallothionein protein Cup1 are located in a tandem array on chromosome VIII. Using a diploid strain that is heterozygous for an insertion of a selectable marker () within this tandem array, and heterozygous for markers flanking the array, we measured interhomolog recombination and intra/sister chromatid exchange in the locus. The rate of intra/sister chromatid recombination exceeded the rate of interhomolog recombination by >10-fold.