Publications by authors named "Halit E Taskin"

Article Synopsis
  • The global rise in obesity has led to the need for clear guidelines combining medical, endoscopic, and surgical methods for effective treatment.
  • An expert panel formed by IFSO-EC created evidence-based recommendations for treating adults with a BMI of 30 or higher, focusing on integrating lifestyle interventions and various weight loss techniques.
  • These guidelines emphasize a comprehensive approach to obesity management, recognizing it as a complex, chronic disease that requires understanding all therapeutic options available.
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  • The study highlights the increasing importance of metabolic and bariatric surgery (MBS) in addressing global obesity, emphasizing the need for rigorous academic and fellowship training for surgeons.
  • A Modified Delphi method involving 89 surgeons from 42 countries was used to establish expert consensus on the necessary criteria for surgeons to obtain privileges for performing MBS, reaching agreement on 29 out of 30 statements.
  • Key consensus points include the requirement for surgeons to hold a general surgery degree, complete a dedicated fellowship, and adhere to defined learning curves for various MBS procedures, alongside maintaining patient data and collaborating in a multidisciplinary team.
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Purpose: There is a lack of evidence for treatment of some conditions including complication management, suboptimal initial weight loss, recurrent weight gain, or worsening of a significant obesity complication after one anastomosis gastric bypass (OAGB). This study was designed to respond to the existing lack of agreement and to provide a valuable resource for clinicians by employing an expert-modified Delphi consensus method.

Methods: Forty-eight recognized bariatric surgeons from 28 countries participated in the modified Delphi consensus to vote on 64 statements in two rounds.

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Background: Laparoscopic splenectomy (LS) is considered the gold standard treatment in adults with idiopathic thrombocytopenic purpura (ITP) refractory to medical therapy. However, the retrieval of the spleen in LS is still a technical challenge, despite the use of various commercial retrieval bags. This study reports the feasibility and reliability of using a saline bag for spleen retrieval in a reduced port splenectomy.

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  • Several studies suggest that a specific mitochondrial DNA deletion may affect metabolism, and this study looked at its relationship with obesity-related issues in fat tissue.
  • The research involved obese individuals undergoing surgery and examined mitochondrial DNA deletions, energy status indicators, and fat tissue composition, finding no significant differences between obese and control groups.
  • The results indicated that while the mitochondrial DNA deletion doesn't significantly affect energy levels in fat tissue, it may relate to changes in lipid structure, offering insights into the connections between mitochondrial deletions and obesity.
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Article Synopsis
  • - Ramadan fasting is a significant Islamic practice, but patients with a history of metabolic/bariatric surgery (MBS) may face unique risks, highlighting the need for better guidance and recommendations regarding fasting safety.
  • - An international survey involving 21 medical centers across 11 countries identified 132 patients who experienced complications while fasting post-MBS, with upper gastrointestinal (GI) issues being the most common.
  • - Complications such as GERD, abdominal pain, and dumping syndrome were reported, and surgical intervention was required for a small percentage of patients; hence, it's crucial to inform MBS patients about potential risks during fasting and to review their medications.
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Article Synopsis
  • Recent advancements like OpenAI's ChatGPT-4 are being explored for their potential use in bariatric surgery decision-making as obesity rates rise.
  • The study involved a survey of thirty bariatric surgeons who assessed ten patient scenarios, comparing their recommendations with those provided by ChatGPT-4.
  • Results showed that ChatGPT-4 aligned with expert opinions 30% of the time, highlighting inconsistencies and the necessity for human expertise in effective treatment decisions.
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Background: This international Young-IFSO survey aims to address variations, trends, and obstacles in bariatric/metabolic surgery (BMS) training globally, since expectations and resources differ among young surgeons.

Methods: The Young-IFSO scientific team designed an online confidential questionnaire with 50 questions analyzing the individual BMS training. The survey link was sent to all IFSO/ASMBS members and was shared in social media.

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Article Synopsis
  • The study compared the effects of a very low-calorie ketogenic diet (VLCKD) and a Mediterranean diet (MD) on weight loss and metabolic health in obese patients preparing for bariatric surgery over a 15-day period.
  • Patients on the VLCKD lost a median of 2.7 kg/m in BMI, while those on the MD lost 1.4 kg/m, with significant reductions in fat percentage and liver size favoring the VLCKD group.
  • Both diets improved cholesterol and LDL levels, but the VLCKD group showed greater overall improvements in metabolic and anthropometric measures, demonstrating its effectiveness for short-term weight loss and health benefits prior to surgery.
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Introduction: This study examined whether 355 obese patients with type 2 diabetes (T2D) of varying duration and severity experienced equivalent weight loss and T2D remission following a newer sleeve gastrectomy (SG) procedure - SG with transit bipartition (SG-TB).

Methods: Primary outcomes were changes in body mass index (BMI), total weight loss (TWL), excess BMI loss (EBMIL), A1C, and diabetes medication use through 24 months.

Results: Between December 2015 and December 2019, 399 patients who underwent SG-TB reached the 2-year time point.

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Aim: Obesity is a disease complicating the course of COVID-19 and SARS-CoV-2 vaccine effectiveness in adults with obesity may be compromised. Our aim is to investigate the spike-protein receptor-binding domain antibody titers against BNT162b2 mRNA and inactivated SARS-CoV-2 (CoronaVac) vaccines in people with severe obesity. It is anticipated that the results to be obtained may provide invaluable information about future SARS-CoV-2 vaccination strategies in this vulnerable population.

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The bariatric food pyramid is a standard for long-term healthy living and nutritional habits of patients who have undergone bariatric surgery, taking their gastric capacity and special nutritional requirements into account. This study aimed to evaluate how the compliance with the pyramid affects the anthropometric change in patients who have undergone bariatric surgery, depending on the period after surgery. 81 patients who have undergone bariatric surgery between August 2016 and September 2018 participated in the study.

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Acute appendicitis is one of the most common abdominal surgical emergencies worldwide. Clinical diagnosis is possible in most of the cases although imaging modalities may become necessary if the diagnosis is uncertain. Appendectomy, preferably the laparoscopic ap-proach, still remains the gold standard treatment to date.

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Background: Metabolic/bariatric surgery has been shown to increase testosterone in males with obesity. This study investigated the effect of the novel metabolic/bariatric surgery procedure, sleeve gastrectomy with transit bipartition (SG-TB), on serum total testosterone and metabolic variable changes in men with obesity and type 2 diabetes.

Methods: In a prospective single-center cohort study, laboratory samples were analyzed preoperatively and at 6 months following SG-TB in patients with a body mass index (BMI) ≥30 kg/m2.

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Article Synopsis
  • Early diagnosis of subclinical cardiovascular disease (CVD) in morbidly obese patients is crucial, and this study examined how sleeve gastrectomy (SG) impacts certain biomarkers related to atherosclerosis.
  • After comparing metabolic and inflammatory markers in patients undergoing SG and a control group, significant differences were observed at baseline, with the surgery group showing marked improvements at 12 months, coinciding with substantial weight loss.
  • The reduction in biomarkers linked to atherosclerosis, including sLOX-1, indicates that SG may help prevent CVD by minimizing endothelial damage, positioning sLOX-1 as a potential marker for cardiovascular issues in morbidly obese individuals.
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Introduction: Tuberous sclerosis complex is an inherited multisystemic disorder with manifestations in various organ systems as a result of a mutation of 1 of 2 tumor suppressor genes, tuberous sclerosis complex-1 or tuberous sclerosis complex-2. Perivascular epithelioid cell tumors have been shown to be associated with these gene mutations and include a variety of tumors such as angiomyolipomas and lymphangioleiomyomatosis.

Patient Concerns: In this report, we present a case of a 28-year-old woman presenting with symptoms of severe abdominal pain and nausea with a medical history of cardiac rhabdomyoma, adenoma sebaceum, Ash leaf spots, bilateral renal angiomyolipomas, and retinal hamartoma, which are manifestations of tuberous sclerosis complex.

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Background: At least 25 metabolic/bariatric procedures have been proposed globally, 5 formally endorsed. A newer procedure, sleeve gastrectomy with transit bipartition (SG + TB), appears to markedly reduce weight and improve metabolic syndrome while being relatively simple technically and protective of long-term nutritional stability. We aimed to investigate SG + TB effectiveness and safety.

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Background: Fasting during Ramadan is one of the five pillars of the Muslim faith. Despite the positive effects of fasting on health, there are no guidelines or clear recommendations regarding fasting after metabolic/bariatric surgery (MBS). The current study reports the result of a modified Delphi consensus among expert metabolic/bariatric surgeons with experience in managing patients who fast after MBS.

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Article Synopsis
  • A pilot study investigated the effects of two home-based exercise programs on post-bariatric surgery patients: one focused solely on aerobic exercise (AE) and the other combined aerobic with progressive resistance training (AEPR).
  • The study found that patients in the AEPR group experienced greater weight loss and improvements in functional capacity, muscle strength, and overall body composition compared to those in the AE group.
  • Both exercise programs improved general health, but the AEPR regimen was significantly more effective in enhancing weight loss and physical performance after three months.
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The management of disappearing colorectal liver metastases in the postadjuvant chemotherapy setting is challenging. We describe a novel technique that facilitates laparoscopic resection of disappearing metastatic liver lesions with great precision. Details of this new technique are described in 2 patients with colorectal cancer synchronously metastatic to the liver.

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Background: Laparoscopic adrenalectomy has gained widespread acceptance. However, the optimal surgical approach to laparoscopic bilateral adrenalectomy has not been clearly defined. The aim of this study is to analyze the patient and intraoperative factors affecting the feasibility and outcome of different surgical approaches to define an algorithm for bilateral adrenalectomy.

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Background: Laparoscopic posterior retroperitoneal (PR) adrenalectomy is preferable in patients with bilateral adrenal masses, as it obviates the need for repositioning. Robotic adrenalectomy has been reported to improve surgeon ergonomics and facilitate dissection. Although robotic bilateral transabdominal lateral adrenalectomy has been described in the literature, to our knowledge, the robotic bilateral PR approach has not been reported before.

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