Design, syntheses, theoretical calculations, MM-GBSA, potential anti-cancer and enzyme activities of novel Schiff base compounds.

In this study, new Schiff base compounds (, and ) were derived from chalcone-derived amine compounds containing halogen groups and 4-hydroxybenzaldehyde. Also, their phthalonitrile compounds (, and ) have been synthesized. The structures of these compounds were elucidated by NMR, FT-IR and Mass spectroscopic methods.

Synthesis of peripheral and non-peripheral substituted metallophthalocyanines containing (E)-3-(5-bromo-2-hydroxphenyl)-1-o-tolyprop-2-en-1-one: Investigation of the photophysical and photochemical properties.

In this study, the novel peripherally (5-7) and non-peripherally (9-11) metallo (zinc, magnesium and lead) phthalocyanine derivatives were synthesized from their (E)-4-(4-bromo-2-(3-oxo-3-o-tolyprop-1-enyl)phenoxy) substituted phthalonitrile precursors (4 and 8). These novel phthalocyanine derivatives including chalcone groups were characterized by spectroscopic techniques such as FT-IR, UV-vis, H NMR, C NMR and MALDI-TOF mass spectra. In the next stage, the photophysical and photochemical properties of synthesized compounds were searched in DMSO which is not cause toxic effects at a certain concentration in biological applications.

The use of new metallophthalocyanines carrying peripherally 4-methyl-N-(3-morpholinopropyl)benzenesulfonamide moieties for the sensitive fluorimetric determination of banned food dye Sudan II in red chili peppers.

The structural elucidation and syntheses methods of new peripherally tetra-substituted MPcs [Cu(6), Co(7), MnCI(8), and Ni(9) phthalocyanines] carrying 4-methyl-N-(3-morpholinopropyl)benzenesulfonamide moieties were reported in the present study. The corroboration of the prepared compounds (3, 5, and 6 to 9) was made by LC-TOF/MS, UV-Vis, Fourier Infrared, H NMR, C NMR, and MALDI-TOF mass spectral data. Herein, we submit a new procedure that uses metallophthalocyanine complexes for the first time as spectrofluorimetric agents to detect and determine health-threatening food additive, Sudan II dye, with a new simpler, cheaper, and faster spectrofluorimetric method instead of time-consuming and expensive HPLC processes.