Publications by authors named "Halil Ibrahim Ellez"
Primary Biliary Cholangitis (PBC) is a chronic cholestatic liver disease typically diagnosed by elevated cholestatic liver enzymes and a positive anti-mitochondrial antibody (AMA) test. The clinical importance of AMA positivity in patients with normal cholestatic liver enzymes is unclear. The aim of this study was to determine the relationship between PBC and AMA positivity detected in individuals with normal cholestatic enzyme levels.
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- - The study investigates the Prognostic Nutritional Index (PNI) as a potential biomarker for predicting survival outcomes in patients with metastatic castration-sensitive prostate cancer (mCSPC), using data from 108 patients treated for at least three months between 2010 and 2021.
- - Results show that patients with a high PNI had significantly better overall survival (OS) and cancer-specific survival (CSS) compared to those with low PNI, with median OS of 65.60 months versus 34.93 months, and median CSS of 48.20 months versus 27.86 months, respectively.
- - Although the study suggests a trend indicating that PNI might affect progression-free survival (PFS),
Renal cell carcinoma (RCC) can cause various paraneoplastic syndromes, including metabolic and hematologic disturbances. Paraneoplastic hypereosinophilia has been reported in a variety of hematologic and solid tumors. Hypereosinophilia due to RCC is very rare and is only available as case reports in the literature.
View Article and Find Full Text PDFObjectives: To compare the survival of first- and second-generation tyrosine kinase inhibitors (TKIs) in patients with rare EGFR exon 18 and exon 20 mutation-positive non-small cell lung cancer (NSCLC).
Materials And Methods: We retrospectively evaluated survival characteristics of 125 patients with EGFR exon 18 and exon 20 mutated NSCLC who received erlotinib or afatinib as first line treatment between 2012 and 2021 from 34 oncology centres. Since exon 20 insertion is associated with TKI resistance, these 18 patients were excluded from the study.