Skin findings in neonates carry a wide differential diagnosis, ranging from self-limiting rashes to something more sinister, as cutaneous changes can be an indicator of a serious underlying infectious process. Even benign rashes can cause great concern for families and providers. Pathologic rashes pose a potential risk to the neonate's health.
View Article and Find Full Text PDFHere we describe a cutaneous neonatal myeloid sarcoma (MS) case with a subsequent diagnosis of acute myeloid leukemia (AML) seven days later. Cytogenetic studies were unusual demonstrating a triple copy of KAT6A abnormality and complex 8;14;22 translocation involving the 8p11.2 region.
View Article and Find Full Text PDFJ Toxicol Environ Health B Crit Rev
April 2022
Percutaneous absorption is of importance given its role in topical medicaments, transdermal drug systems, and dermatotoxicology. Many factors influence percutaneous penetration, including anatomical region, although little is currently known regarding this parameter. Hence, the aim of this study was to summarize existing data on regional variation in percutaneous penetration in human models.
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