Publications by authors named "Haley A Partlow"
Article Synopsis
- Despite vaccines against COVID-19, SARS-CoV-2 continues to spread, prompting the need for new vaccines with better effectiveness.
- Researchers developed an adjuvanted subunit vaccine using the receptor-binding domain (RBD) of the virus's spike protein and synthetic adjuvants to enhance immune response.
- Their findings show that adding specific TLR (toll-like receptor) ligands improves immune response types and boosts antibody production against SARS-CoV-2.
A diversity of vaccines is necessary to reduce the mortality and morbidity of SARS-CoV-2. Vaccines must be efficacious, easy to manufacture, and stable within the existing cold chain to improve their availability around the world. Recombinant protein subunit vaccines adjuvanted with squalene-based emulsions such as AS03™ and MF59™ have a long and robust history of safe, efficacious use with straightforward production and distribution.
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