Ameliorating Effect of Olive Leaf Extract on Cyclosporine-induced Nephrotoxicity in Rats.

Introduction: Olive leaves are traditionally used in the Mediterranean basin in many medical conditions for its potent antioxidant activity. Cyclosporine A, a well-known immunosuppressant, can induce nephrotoxicity through oxidative stress. This study investigated the effect of olive leaf extract (OLE) on cyclosporine-induced nephrotoxicity in rats.