Screening for congenital defects and genetic diseases of the fetus at University Hospital in Olomouc and sending/ reporting to the National register of reproductive health in the Czech Republic.

Objective: The aim of the study was to analyze the results of the screening for congenital defects (CD) and genetic diseases (GD) of the fetus in the Fetal Medicine Centre at the Department of Obstetrics and Gynecology, University Hospital in Olomouc.

Materials And Methods: Prospective cohort study. In the period from 1 January 2020 to 31 December 2021, a total of 14,460 health services were performed on 4,916 pregnant women.

Transabdominal amniocentesis in expectant management of preterm premature rupture of membranes: A single center prospective study.

Aims: The aim of this study was to evaluate the role of IL-6 point-of-care test in amniotic fluid obtained from serial amniocentesis in expectantly managed women with PPROM between 24 and 34 weeks of gestation.

Methods: We conducted a prospective observational cohort study which included 62 pregnant women with PPROM in gestational weeks between 22+0 and 34+0. Women aged >18 years were eligible if they presented with PPROM and a singleton pregnancy.

The association between mode of birth delivery and attention-deficit/hyperactivity disorder: a systematic review protocol of epidemiological evidence.

Caesarean section is currently the most frequently performed intervention after episiotomy in obstetrics and one of the most common abdominal operations overall. Rates of caesarean section have been rising globally. Given the increasing rate worldwide it is therefore necessary and important to understand how caesarean section affects child development.

The role of nCD64 in the diagnosis of neonatal sepsis in preterm newborns.

Background: Diagnosing neonatal sepsis is difficult, particularly in preterm newborns. A promising method appears to be evaluation of cell surface markers by flow cytometry.

Methods: This prospective study investigated 217 newborns suspected of having early- or late-onset neonatal sepsis.

Bilateral position-related ulnar neuropathy at elbow in pediatric population and review of the literature.

Perioperative ulnar neuropathies attributed to inappropriate arm positioning and padding during surgical procedures are commonly found in adults. However, their extremely rare incidence in the pediatric population may cause absent awareness of the risk of nerve injury in anesthetized pediatric patients. Furthermore, young patients respond to conservative treatment of neuropathy less favorably than adults and their response also depends on the pathomechanism of the ulnar nerve injury.

Kinematic analysis of preterm newborns' spontaneous movements for postural activity assessment.

Aims: The objectives of this pilot study were to assess the potential use of 3D videography for analyzing the motion of the body center of mass (COM) in newborns and to determine differences in spontaneous movements between preterm and full-term infants.

Methods: The group comprised 10 preterm newborns (gestational age at birth between 26 and 37 weeks; birth weight 800 to 2960 g; gestational age at the time of examination 34 to 39 weeks) and 10 full-term infants (gestational week 38 to 41; birth weight 2810 to 4360 g). To determine the range of motion of the COM, 3D videography was used (2 cameras, 25 Hz).

[Developmental impairment of children with very low and extremely low birth weight at 24 months corrected age, born in the Czech Republic in 2000-2009].

Objective: To evaluate the incidence of neonatal morbidity (NM), and developmental impairments (DIs) of very low (VLBW) and extremely low birth weight (ELBW) infants born in 2000-2009.

Design: Epidemiological study.

Setting: Outpatient clinics for children with perinatal risk at the regional neonatal centers.

[Changes in the developmental outcome of very low and extremely low birth weight infants at 24 months' corrected age born in 1997-2007].

Objective: To describe the incidence of developmental impairments (DI) among very low birth weight (VLBW) infants at 24 months' corrected age, born in perinatal centers in 1997-2007, and evaluate their changing prognosis of intact development.

Design: Prospective epidemiological study.

Setting: Follow-up clinics of neonatal centers level III.

Diagnostic accuracy of postnatal ultrasound screening for urinary tract abnormalities.

The study was aimed at (1) the determination of the incidence of abnormalities of the urinary tract in newborn infants detected by postnatal ultrasound screening, and (2) the evaluation of the diagnostic accuracy of postnatal ultrasound screening for detecting surgical urinary tract abnormalities. The prospective study was of full-term neonates born in the University Hospital of Olomouc in 2005-2008 who underwent renal ultrasound screening after 72 h of life. Significant findings were recorded.

Chronic smoking and its effect on arterial stiffness.

Aims: The goal of this study was to investigate the effect of chronic smoking on arterial stiffness at a peripheral site using pulse wave analysis.

Methods: Forty two non-smokers (17 males, 25 females) of average age 20.2 +/- 1.

Parameters describing the pulse wave.

Pulse wave analysis permits non-invasive assessment of arterial elasticity indices. The contour varies in different parts of the circulation. It depends on physiological or pathophysiological conditions of the organism.

Derivation of sonograph quality parameters by the use of point spread function analysis.

A measuring system evaluating a Point Spread Function generated in an ultrasonographic image by scanning a spherical target was developed. The target is moved in measuring bath filled by water over scanned volume via 3D computer controlled positioning system. A video signal obtained is converted to digital form and analyzed by original software to derive various objective parameters of the imager as follows: Focal areas in both the azimuth and the elevation directions, Ultrasound scanning lines visualisation, Manufacturer preloaded TGC, Width of the scanning plane, Side lobe levels and Amplification uniformity in the azimuth direction.

In vitro study of reactive oxygen species production during photodynamic therapy in ultrasound-pretreated cancer cells.

Several recent studies bring evidence of cell death enhancement in photodynamic compound loaded cells by ultrasonic treatment. There are a number of hypotheses suggesting the mechanism of the harmful ultrasonic effect. One of them considers a process in the activation of photosensitizers by ultrasonic energy.

Pulse wave variability within two short-term measurements.

Background: Pulse wave analysis permits non-invasive assessment of indices of arterial elasticity. Decreased arterial elasticity results in higher pulse wave velocity and therefore earlier wave reflection.

Aim: The aim of this study was to evaluate the short-term variability for measurement of surface arteries.

A contribution to sonograph image quality estimation using point spread function.

In medical sonography, sonograph image quality is an essential aspect for the safety of both patient and doctor. Its evaluation therefore requires an accurate and objective method for measurement. In this regard, a number of methods are in current use.

Surface artery volume pulse wave measurement - verification of a new method.

The aim of this paper is to prove the possible reproducibility of measurement with a new developed device for artery elasticity monitoring and determining the standard of major pulse wave parameters. As a measurement sensor, a conic probe with thin convex membrane was used. This technique allows setting an arbitrary pressure to a measured surface artery.

[Early maternal and neonatal morbidity after spontaneous and surgically-assisted vaginal delivery].

Objective: To evaluate the differences in early maternal and neonatal morbidity after spontaneous delivery, forceps delivery and vacuum-extraction.

Design: Retrospective clinical study.

Setting: Department of Obstetrics and Gynecology, University Hospital, Palacký University, Olomouc.

A method of local skin perfusion detection.

On the epidermal surface there are inhomogeneities which manifest as, among other things, lower local impedance. These regions include Head's zones, sweat glands, and also the so-called acupuncture points. The aim of this paper is to examine the effect of skin perfusion on epidermal impedance at the acupuncture points.

[Financing of education and research in universities].

Universities in the Czech Republic undergo a process of deep changes. There are different perspectives concerning the correctness of the way started with this process. This contribution shows the possibilities which the ministry of Education, Youth and Sports can use to support the quality of teaching as well as the quality of science and research at our universities.

[The concept of practical teaching of medical informatics at the Medical School of Palacký University in Olomouc].

The method and conditions of medical information technology teaching represent a direct reflection of both significant progress of information technology and change in public approach to computer techniques. Over the years, the content of the course has been changed to a large extent. It is a result of the existing wide scale of available program products, modernization of local computer network and information technology classrooms and especially common attempt to availability of Internet.

[Results of measurement of resolution capability of ultrasonographic equipment using our new method].

The quality of sonographic instruments is vital for accurate medical diagnosis. To overcome one subjective problem associated with sonographic equipment, we have designed a system for objective instrument evaluation that is simple, accurate and valid. The system described fulfills the criteria for solving the outlined problem and enables us now to measure the parameters of both the axial and transversal resolutions.

[Laparoscopic cholecystectomy].

The authors present an account of their experience assembled during one year with laparoscopic operations of the gallbladder. They indicated 248 patients for CHE incl. 237, i.