Publications by authors named "Haleh Pak"

Article Synopsis
  • Postoperative urinary dysfunction is a major issue for patients who have undergone rectal cancer surgery, and the effectiveness of pelvic floor muscle training (PFMT) in this context is still being evaluated.
  • A clinical trial with 79 patients demonstrated that starting Kegel exercises shortly after surgery resulted in notable improvements in urinary symptoms compared to standard care, with adherence linked to better outcomes and no adverse effects reported.
  • The study suggests that early Kegel exercises may help improve urinary function post-surgery, calling for further research to refine patient care approaches.
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  • Crohn's disease perianal fistulae often don't respond well to standard therapies, but mesenchymal stem cell (MSC)-derived exosomes have shown potential as a treatment, being deemed safe in previous studies.
  • A phase II clinical trial was conducted with 23 patients suffering from refractory perianal fistulas, where exosomes were injected directly into the fistula tracts over a period of 6 months.
  • Results indicated that 60% of patients achieved complete fistula closure, and overall, 69.7% of treated fistula tracts showed significant closure, along with some observed improvements in discharge from the tracts.
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Background: Identifying the severity of trauma to provide timely and adequate treatment and predict the prognosis are some of the significant challenges in trauma management. Increased red blood cell distribution width (RDW) is associated with several pathologies and associated mortality. This study aims to evaluate the RDW in predicting 24 h and 30-day mortality among multiple trauma patients.

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Ileus and pseudo-obstruction are clinical syndromes that are among the most common postoperative complications. Identifying an effective treatment approach for these conditions is essential. Therefore, the aim of this study is to investigate the effect of Dimethicone on preventing ileus in patients with pelvic and femoral fractures.

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  • This study investigates how COVID-19 affects patients with chest trauma who need emergency surgery, comparing those infected with COVID-19 to those who are not.
  • Out of 56 trauma patients, 21 had COVID-19; symptoms were mild and hospitalization was shorter for COVID-19 patients compared to non-infected patients.
  • While there were notable differences in hospitalization length, ICU admissions, and pneumonia rates, the mortality rates were similar for both groups.
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Sigmoid volvulus accounts for 20%-50% of colonic obstructions in Eastern countries. This occurs mostly in patients with a lack of mobility and a history of chronic constipation. There are some very known complications of a undescended intra-abdominal testicle such as cancer, ischemia, and infertility; But the rotation of the colon around the spermatic cord of one UDT is a very rare phenomenon that there is no similar report.

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Article Synopsis
  • * Eleven patients with long-term fistulas received exosome injections, and after six months, most showed improvement, with several achieving complete resolution of their condition.
  • * The findings suggest that MSC-derived exosomes are safe and effective in treating complex perianal fistulas, highlighting their potential for future research and clinical use.
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Background And Aims: Ventilator-associated pneumonia is highly prevalent nosocomial infection among patients under mechanical ventilation. Bronchoalveolar lavage (BAL) is effective in identifying the type of pathogen involved and determine the course of antibiotic. The aim of this study was to evaluate the prevalence of different pathogens involved in ventilator-associated pneumonia (VAP) and associated antibiotic resistance and sensitivity pattern.

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Objective: Sternal fracture may be associated with major and serious injuries. In this study, the complications associated with isolated sternal fracture in trauma patients are evaluated based on radiographic and cardiac findings.

Methods: This retrospective study was performed on patients with isolated sternal fractures admitted to the emergency department of (XXX) Madani Educational-Medical.

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Background And Aims: Acute appendicitis is one of the common causes of abdominal surgeries, however, the rate of negative appendectomy is as high as 20% as the diagnosis of appendicitis is challenging. The study aimed to evaluate complete blood count (CBC)-associated parameters among positive and negative appendectomy patients and determine their diagnostic importance.

Methods: In this cross-sectional study, patients who suspected of acute appendicitis were included.

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We report a case of cooccurrence of xanthogranulomatous and emphysematous pyelonephritis along with necrotizing fasciitis (NF) of scrotum and premium in a patient was nondiabetic and the history of kidney stones. This case a unique presentation of NF due to two pyelonephritis causing fournier gangrene. Surgical management and antibiotics provide an effective management of the disease.

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Background: Advancements in diagnostic and therapeutic sciences have allowed early diagnosis and treatment of cancer. Colorectal cancer is one of the most commonly reported cancers, particularly in elderly patients.

Methods: Open and laparoscopic surgeries are used for the removal of the tumor, along with chemotherapy, depending on the stage of cancer.

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A 41-year-old man with abdominal enlargement, as a result of large retroperitoneal Schwannoma, was reported to our center. It was seen to have caused the displacement of the colon and was attached to the presacral region of the spine. Following the diagnosis, successful resection of Schwannoma was achieved.

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Antiphospholipid antibody syndrome (APS) is known to cause hypercoagulability, affecting a wide range of vessels, systematically. A 56-year-old woman was referred to our center with severe epigastric pain, with the history of APS. She was treated with packed cells, fresh frozen plasma and anticoagulation therapies.

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