Insulin-like growth factor binding protein-3 in preterm infants with retinopathy of prematurity.

Background: Retinopathy of prematurity (ROP) is the main cause of visual impairment in preterm newborn infants.

Objective: This study was conducted to determine whether insulin-like growth factor binding protein -3 (IGFBP-3) is associated with proliferative ROP and has a role in pathogenesis of the disease in premature infants.

Materials And Methods: A total of 71 preterm infants born at or before 32 weeks of gestation participated in this study.