Publications by authors named "Hale Molla Kafi"
Introduction: Pulmonary exacerbations increase the requirement of aminoglycoside (AG) antibiotics in people with cystic fibrosis (pwCF). Several studies have shown that AGs have a cumulative effect on ototoxicity. We aimed to investigate the relationship between AG exposure and ototoxicity by using 3 different methods in patients with CF.
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- The study analyzes data from the CF Registry of Turkey to measure the rate of decline in pulmonary function (ppFEV1) among cystic fibrosis patients and identifies risk factors related to this decline.
- It found that patients with more severe disease (ppFEV1 < 40) had poorer nutritional status and a higher prevalence of chronic Pseudomonas aeruginosa infection compared to those with better lung function.
- The results emphasize the need for regular monitoring of patients with normal initial ppFEV1 and early treatment for P. aeruginosa infections, highlighting the crucial role of proper nutrition in managing cystic fibrosis.