Publications by authors named "Hala Khan"
Article Synopsis
- * Researchers found that while most children had normal neurodevelopmental scores, a significant number displayed issues, especially as they grew older; specific factors like low birth weight and maternal education influenced outcomes.
- * The findings suggest that children with sTOF may have elevated developmental concerns, and although the type of surgical intervention didn't seem to affect these outcomes, other risks like genetic syndromes are important to consider for early intervention.
To evaluate the association between initial management strategy of neonatal symptomatic Tetralogy of Fallot (sTOF) and later health-related quality of life (HRQOL) outcomes. We performed a multicenter, cross-sectional evaluation of a previously assembled cohort of infants with sTOF who underwent initial intervention at ≤ 30 days of age, between 2005 and 2017. Eligible patients' parents/guardians completed an age-appropriate Pediatric Quality of Life Inventory, a Pediatric Quality of Life Inventory Cardiac Module Heart Disease Symptoms Scale, and a parental survey.
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- - The study investigates how preoperative levels of Carbohydrate Antigen 19-9 (CA19-9) relate to the presence of occult metastasis in pancreatic cancer patients.
- - Researchers analyzed data from 10 studies involving 1,431 patients, finding that those with metastasis had significantly higher mean CA19-9 levels compared to those without.
- - A cut-off CA19-9 level of 336 was identified, with high sensitivity (90%) and specificity (80%) for predicting metastasis, suggesting its potential use in future clinical studies.
Background: Neonates with tetralogy of Fallot and symptomatic cyanosis (sTOF) require early intervention.
Objectives: This study sought to perform a balanced multicenter comparison of staged repair (SR) (initial palliation [IP] and subsequent complete repair [CR]) versus primary repair (PR) treatment strategies.
Methods: Consecutive neonates with sTOF who underwent IP or PR at ≤30 days of age from 2005 to 2017 were retrospectively reviewed from the Congenital Cardiac Research Collaborative.