Heparin/N-acetylcysteine: an adjuvant in the management of burn inhalation injury: a study of different doses.

Purpose: Nebulized heparin may reduce fibrin cast formation and reduce the degree of airway obstruction in burn inhalation injury.

Methods: Twenty-nine patients admitted to burn intensive care unit (ICU) within 24 hours of burn inhalation injury were included in this prospective double-blinded randomized study. Group H5 received nebulized heparin sulfate 5,000 IU, and group H10 received nebulized heparin sulfate 10,000 IU.