Experiences with the Use of Video Bikes and Virtual Reality in Nursing Homes - a Qualitative Study.

Purpose: The aim of the study was to explore how health personnel experience use of video bikes and VR (Virtual Reality) in nursing homes.

Methodology: The study had an explorative design with a qualitative approach.

Results: Nine individual interviews were conducted with health personnel.

F-FACBC and F-FDG PET/MRI in the evaluation of 3 patients with primary central nervous system lymphoma: a pilot study.

Background: This PET/MRI study compared contrast-enhanced MRI, F-FACBC-, and F-FDG-PET in the detection of primary central nervous system lymphomas (PCNSL) in patients before and after high-dose methotrexate chemotherapy. Three immunocompetent PCNSL patients with diffuse large B-cell lymphoma received dynamic F-FACBC- and F-FDG-PET/MRI at baseline and response assessment. Lesion detection was defined by clinical evaluation of contrast enhanced T1 MRI (ce-MRI) and visual PET tracer uptake.

Added Value of [18F]PSMA-1007 PET/CT and PET/MRI in Patients With Biochemically Recurrent Prostate Cancer: Impact on Detection Rates and Clinical Management.

Background: Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) can change management in a large fraction of patients with biochemically recurrent prostate cancer (BCR).

Purpose: To investigate the added value of PET to MRI and CT for this patient group, and to explore whether the choice of the PET paired modality (PET/MRI vs. PET/CT) impacts detection rates and clinical management.

Diagnostic accuracy of anti-3-[F]-FACBC PET/MRI in gliomas.

Purpose: The primary aim was to evaluate whether anti-3-[F]FACBC PET combined with conventional MRI correlated better with histomolecular diagnosis (reference standard) than MRI alone in glioma diagnostics. The ability of anti-3-[F]FACBC to differentiate between molecular and histopathological entities in gliomas was also evaluated.

Methods: In this prospective study, patients with suspected primary or recurrent gliomas were recruited from two sites in Norway and examined with PET/MRI prior to surgery.

Associations between detectable circulating tumor DNA and tumor glucose uptake measured by F-FDG PET/CT in early-stage non-small cell lung cancer.

Background: The low level of circulating tumor DNA (ctDNA) in the blood is a well-known challenge for the application of liquid biopsies in early-stage non-small cell lung cancer (NSCLC) management. Studies of metastatic NSCLC indicate that ctDNA levels are associated with tumor metabolic activity as measured by F-fluorodeoxyglucose positron emission tomography (F-FDG PET/CT). This study investigated this association in NSCLC patients considered for potentially curative treatment and explored whether the two methods provide independent prognostic information.

Prognostic value of combined MTV and ADC derived from baseline FDG PET/MRI in aggressive non-Hodgkins lymphoma.

Purpose: The aim of this prospective study was to investigate the prognostic value of metabolic tumor volume (MTV) and apparent diffusion coefficient (ADC) from baseline FDG PET/MRI compared to established clinical risk factors in terms of progression free survival (PFS) at 2 years in a cohort of diffuse large B-cell Lymphoma (DLBCL) and high-grade-B-cell lymphoma (HGBCL).

Methods: Thirty-three patients and their baseline PET/MRI examinations were included. Images were read by two pairs of nuclear medicine physicians and radiologists for defining lymphoma lesions.

Diagnostic Value of 18 F-FACBC PET/MRI in Brain Metastases.

Purpose: The study aims to evaluate whether combined 18 F-FACBC PET/MRI could provide additional diagnostic information compared with MRI alone in brain metastases.

Patients And Methods: Eighteen patients with newly diagnosed or suspected recurrence of brain metastases received dynamic 18 F-FACBC PET/MRI. Lesion detection was evaluated on PET and MRI scans in 2 groups depending on prior stereotactic radiosurgery (SRS group) or not (no-SRS group).

Palliative care in home health care services and hospitals - the role of the resource nurse, a qualitative study.

Background: The role of the resource nurse aims at bridging the gap between the specialist nurses and the nurses who work in non-specialist wards. The role is established internationally and used in a wide area of clinical settings. The resource nurse is promoting evidence-based practice.

A comparison of FDG PET/MR and PET/CT for staging, response assessment, and prognostic imaging biomarkers in lymphoma.

The aim of the current study was to investigate the diagnostic performance of FDG PET/MR compared to PET/CT in a patient cohort including Hodgkins lymphoma, diffuse large B-cell lymphoma, and high-grade B-cell lymphoma at baseline and response assessment. Sixty-one patients were examined with FDG PET/CT directly followed by PET/MR. Images were read by two pairs of nuclear medicine physicians and radiologists.

Palliative care in the community - the role of the resource nurse, a qualitative study.

Background: Approaches involving resource nurses have been used in several fields of practice to enhance quality of care. A literature review reveals limited research on the role of the resource nurse in palliative care in the community.

Aim: To explore experiences related to the role of the resource nurse in palliative care in the setting of nursing homes in Norway.

F-FACBC PET/MRI in the evaluation of human brain metastases: a case report.

Background: Patients with metastatic cancer to the brain have a poor prognosis. In clinical practice, MRI is used to delineate, diagnose and plan treatment of brain metastases. However, MRI alone is limited in detecting micro-metastases, delineating lesions and discriminating progression from pseudo-progression.

[A woman in her fifties with left bundle branch block and recurrent arrhythmias].

Background: Sarcoidosis is a multi-system inflammatory disorder resulting in the formation of non-caseating granulomas in various parts of the body. Cardiac involvement is associated with worse prognosis, probably due to the destructive effects the granulomas can have on the electrical conduction system. The diagnosis of cardiac sarcoidosis can be challenging due to the limited accuracy of various clinical criteria.

Detection of Recurrent Prostate Cancer With F-Fluciclovine PET/MRI.

Objective: Simultaneous PET/MRI combines soft-tissue contrast of MRI with high molecular sensitivity of PET in one session. The aim of this prospective study was to evaluate detection rates of recurrent prostate cancer by F-fluciclovine PET/MRI.

Methods: Patients with biochemical recurrence (BCR) or persistently detectable prostate specific antigen (PSA), were examined with simultaneous F-fluciclovine PET/MRI.

Prostate-Specific Membrane Antigen PET/Magnetic Resonance Imaging for the Planning of Salvage Radiotherapy in Patients with Prostate Cancer with Biochemical Recurrence After Radical Prostatectomy.

This article presents an overview of the current literature on PET imaging with prostate-specific membrane antigen ligands, especially focusing on the potential role of simultaneous PET/magnetic resonance imaging for the planning of salvage radiotherapy in patients with prostate cancer with biochemical recurrence after radical prostatectomy.

18F-FACBC PET/MRI in Diagnostic Assessment and Neurosurgery of Gliomas.

Purpose: This pilot study aimed to evaluate the amino acid tracer F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas.

Materials And Methods: Eleven patients with suspected primary or recurrent low- or high-grade glioma received an F-FACBC PET/MRI examination before surgery. PET and MRI were used for diagnostic assessment, and for guiding tumor resection and histopathological tissue sampling.

The Effect of Including Bone in Dixon-Based Attenuation Correction for F-Fluciclovine PET/MRI of Prostate Cancer.

The objective of this study was to evaluate the effect of including bone in Dixon-based attenuation correction for F-fluciclovine PET/MRI of primary and recurrent prostate cancer. F-fluciclovine PET data from 2 PET/MRI studies-one for staging of high-risk prostate cancer (28 patients) and one for diagnosis of recurrent prostate cancer (81 patients)-were reconstructed with a 4-compartment (reference) and 5-compartment attenuation map. In the latter, continuous linear attenuation coefficients for bone were included by coregistration with an atlas.

Multimodal F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma.

Background: Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, there is a risk of undergrading caused by histopathologic sampling errors. MRI has limitations in identifying tumor grade and type, detecting diffuse invasive growth, and separating recurrences from treatment induced changes.