Publications by authors named "Hakki Perk"

Introduction: Both hypertension and β-blocker drugs used for treating hypertension (HT) can cause erectile dysfunction (ED). Nebivolol, unlike other β-blockers, may not cause impotence since it increases the release of Nitric Oxide (NO), which is the main mediator of erection. This study investigated the effect of Nebivolol and Metoprolol on erectile functions in hypertensive men.

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Article Synopsis
  • This study evaluated the effectiveness of different biopsy methods (6-, 10-, and 12-core) for diagnosing prostate cancer in patients with renal failure, totaling 122 participants.
  • Out of these patients, 30.3% were found to have prostate cancer, with the 12-core technique showing the highest detection rate at 30.7%.
  • The findings suggest that using a minimum of a 10-core strategy, especially incorporating the 12-core method, can enhance cancer detection rates, particularly for those with elevated PSA levels.
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The aim of this study was to assess the cadmium (Cd) toxicity on renal nitric oxide synthase (NOS) isoenzymes. The study was carried out on 18 inbred male (Cd group: 10 and control group: 8) Wistar rats. Cd group received drinking water containing 15 mg/L Cd for 30 days; and at the end of the 30 days, plasma Cd was analysed.

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Cavernous hemangioma is a congenital, benign vascular tumor that occurs in the deep dermis and subcutaneous tissue. Scrotal hemangiomas are rare entities and are usually diagnosed in childhood. Adult scrotal hemangiomas are also extremely rare.

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Objective: Bone metastasis is a major cause of morbidity in prostatic cancer. Therefore, detecting and monitoring bone lesions are crucial for treatment of prostatic carcinoma. We aimed to evaluate total body bone mineral density and regional bone mineral density in patients with prostate cancer with and without metastases, and to compare them with bone scintigraphy.

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Objectives: Prostate cancer is the most frequently diagnosed malignancy. Luteinizing hormone-releasing hormone (LH-RH) agonists are used in most patients with locally advanced and metastatic prostate cancer, and decrease testosterone production. We aimed to find out the effects of androgen deprivation therapy with LH-RH agonist on the hand function, quality of life, and mood of the patients with prostate cancer.

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Objectives: To evaluate whether assessment of experimental pain perception using the modified tourniquet test before a biopsy procedure could predict the pain scores during transrectal ultrasound-guided prostate biopsy. However, the relationship between the experimental pain assessment before prostate biopsy and the pain scores during the biopsy procedure has not been established.

Methods: A total of 67 men who underwent transrectal ultrasound-guided 12-core prostate biopsy were prospectively enrolled in the study.

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Objective: To assess the relationship between inflammatory cell infiltration and tumor type, stage and grade, the presence of multifocality and survival in tumors and in tumor-free normal parenchyma.

Material And Methods: A total of 99 patients who underwent radical nephrectomy for renal cell carcinoma (RCC) between 1995 and 2001 and were subsequently followed up were included in the study. Formalin-fixed, paraffin-embedded tissues from the patients were reassessed by a pathologist and inflammation in both tumor and normal renal tissue was scored using a five-point scale.

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Introduction: We studied the various stone, renal, and therapy factors that could affect steinstrasse formation after shock wave lithotripsy (SWL) to define their predictive value.

Patients And Methods: Between May 1999 and September 2002, 563 patients were treated with a Stonelight V3 lithotriptor. A steinstrasse was recorded in 46 patients.

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A 42-year-old man presented with right lower quadrant abdominal pain and dysuria. The bladder was displaced to the right side of the pelvis in excretory urography. Abdominal CT revealed a mass in right adrenal gland, measuring 8 cm in diameter.

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Insulin-like growth factor (IGF)-1, a mitogenic and anti-apoptotic peptide, can affect the proliferation of epithelial cells, and is thought to play a role in cancer development. The free IGF-1 represents the biologically active fraction of IGF-1. We hypothesised that there is a difference in free IGF-1 levels in the urine and serum from patients with TCC and normal subjects.

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Background: The objective was to study prospectively the effectiveness of tension-free vaginal tape as an ambulatory and minimal invasive operation for the treatment of female stress incontinence.

Methods: The tension-free vaginal tape procedure was performed in 25 patients with genuine stress incontinence and they were followed for a 2-year period. All patients were diagnosed with urodynamics to have genuine stress incontinence.

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Background: We describe a new operative technique for the surgical treatment of bladder cancer.

Methods: Male patients with invasive bladder cancer were managed by radical cystoprostatectomy using a technically different approach than the conventional method. The main feature of this method includes a small vertical incision between pubis and umbilicus, keeping the abdominal peritoneum closed during the surgery.

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Malignant urachal lesions are exceedingly rare and occur predominantly in adult life. In this case report, an adult patient with urachal carcinoma is presented with abdominal plain film, intravenous urography, gray-scale ultrasonography (US), Doppler US, and computed tomography (CT). Doppler US successfully showed the neovascularity with low resistive index value in the urachus tumor.

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Objective: The purpose of this study was to evaluate the accuracy of magnetic resonance imaging (MRI) in the pre and postoperative assessment of stress urinary incontinence.

Methods: Fifteen female patients with clinical evidence of stress urinary incontinence were included in this prospective study. All the patients underwent MRI in the supine position both preoperatively and postoperatively.

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Objectives: To evaluate the effects of ileal bladder substitution or colonic Indiana pouch on skeletal bone density and various biochemical parameters related to bone metabolism.

Patients And Methods: In 27 patients with urinary diversion and 14 controls with benign urologic disease, bone mineral density (BMD), assessed by dual-photon absorptiometry; serum electrolyte, creatinine, alkaline phosphatase and parathyroid hormone levels were determined, and capillary blood gas analysed. BMD was measured in the lumbar spine and the femur neck.

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In this study, the lead, cadmium, nickel, and aluminum concentrations were analyzed in inner nucleus and outer crust parts of various kinds of urinary calculi, and the results obtained were statistically compared. Significant differences were found among the element concentrations in the different stone groups. In general, higher element concentrations were found in the nuclei as compared with the crust parts.

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A patient with vaginal agenesis presented with complaints of urethral damage due to urethral coitus. We performed a urethrospincteric reconstruction and formation of a new vagina using the bladder flap and the urethra which was used for coitus, respectively. To the best of our knowledge, this is the first report of this procedure.

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