Atom probe tomography (APT) was utilized to supplement scanning electron microscopy (SEM) characterization of a precipitation strengthening nickel-based superalloy, Alloy 247LC, processed by laser powder bed fusion (L-PBF). It was observed that the material in the as-built condition had a relatively high strength. Using both SEM and APT, it was concluded that the high strength was not attributed to the typical precipitation strengthening effect of γ'.
View Article and Find Full Text PDFThe manufacturing of parts from nickel-based superalloy Alloy 247LC by laser powder bed fusion (L-PBF) is challenging, primarily owing to the alloy's susceptibility to cracks. Apart from the cracks, voids created during the L-PBF process should also be minimized to produce dense parts. In this study, samples of Alloy 247LC were manufactured by L-PBF, several of which could be produced with voids and crack density close to zero.
View Article and Find Full Text PDFBackground: The productive capacity of retired people is usually not valued. However, some retirees produce much more than we might expect. This diary-based study identifies the activities of older people, and suggests some value mechanisms.
View Article and Find Full Text PDFObjectives: The clinical effectiveness and cost-effectiveness of implantable cardioverter defibrillators (ICD) for arrhythmias was assessed.
Methods: A systematic review of the literature of systematic reviews and randomized controlled trials that reported mortality outcomes associated with implantable cardioverter defibrillators compared with antiarrhythmic drug therapy in people at risk of sudden cardiac death due to arrhythmias was undertaken. Economic evaluations were also sought.
Objectives: To assess the clinical-effectiveness and cost-effectiveness of pegylated interferon alfa (2a and 2b) combined with ribavirin in previously untreated patients with moderate to severe chronic hepatitis C, compared with the current standard treatment, which is nonpegylated interferon alfa combined with ribavirin.
Methods: Systematic review and economic evaluation. A sensitive search strategy was applied to several electronic bibliographic databases.
To increase the knowledge of the final phase of acute myeloid leukaemia (AML) a retrospective review of the medical and nursing records of 106 adult patients with AML who had died in 1995-1997 was made. A total of 27 patients were treated with curative intent at the time of death and 79 patients were prescribed palliative care. From the documentation, an evaluation of the frequency and severity of bleeding and pain episodes was made during their last week in life, and the occurrence of infection criteria was studied.
View Article and Find Full Text PDFObjective: To characterise patients who collect their prescribed medicines from pharmacy representatives and compare them with those using regular pharmacies.
Method: Data were collected from the prescriptions delivered via pharmacy representatives and by questionnaires to the patients. Data for pharmacies were obtained from the Swedish drug statistics.