Publications by authors named "Hajer Ben Ismail"
Isolated Cutaneous Chronic Lymphocytic Leukemia: A Case Report.
J Investig Med High Impact Case Rep
May 2024
Article Synopsis
- Skin lesions occur in 4% to 20% of patients with chronic lymphocytic leukemia (CLL) and are less common than in T-cell leukemia.
- These lesions often present as leukemic cutis or secondary conditions like urticaria, itching, and cutaneous vasculitis.
- The case discussed involves a patient whose skin lesions led to the late diagnosis of isolated cutaneous CLL, highlighting the need for improved awareness and prompt diagnosis to enhance treatment outcomes.
Background: In the literature, reported cases of Acquired hemophilia A (AHA) induced by COVID-19 vaccination occurred after Adenoviral Vector Deoxyribonucleic Acid (DNA)- and SARS-CoV-2 Messenger Ribonucleic acid (mRNA)-Based vaccines. Here, and to the best of our knowledge, we report the first case of AHA occurring after an inactivated Sinovac-coronavac COVID-19 vaccine.
Case Presentation: A 69-year-old Tunisian male patient consulted for severe left leg pain limiting physical mobility due to a 5*6 cm large ecchymosis located at the left inner thigh, having spontaneously appeared 5 days prior consultation and without notion of trauma.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in December 2019, causing millions of deaths all over the world, and the lack of specific treatment for severe forms of coronavirus disease 2019 (COVID-19) have led to the development of vaccines in record time, increasing the risk of vaccine safety issues. Recently, several cases of thrombotic thrombocytopenic purpura (TTP) have been reported following COVID-19 vaccination. TTP is a rare disease characterized by thrombocytopenia, microangiopathic hemolytic anemia and ischemic end-organ lesions.
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