Role of cold shock proteins B and D in subsp. physiology and virulence in lumpfish ().

Cold shock proteins (Csp) are pivotal nucleic acid binding proteins known for their crucial roles in the physiology and virulence of various bacterial pathogens affecting plant, insect, and mammalian hosts. However, their significance in bacterial pathogens of teleost fish remains unexplored. subsp.

Systematic analysis of ocular features and responses of cultured spotted wolffish (Anarhichas minor).

A better understanding of unique anatomical and functional features of the visual systems of teleost fish could provide key knowledge on how these systems influence the health and survival of these animals in both wild and culture environments. We took a systematic approach to assess some of the visual systems of spotted wolffish (Anarhichas minor), a species of increasing importance in North Atlantic aquaculture initiatives. The lumpfish (Cyclopterus lumpus) was included in these studies in a comparative manner to provide reference.

Inactivated Aeromonas salmonicida impairs adaptive immunity in lumpfish (Cyclopterus lumpus).

Aeromonas salmonicida, a widely distributed aquatic pathogen causing furunculosis in fish, exhibits varied virulence, posing challenges in infectious disease and immunity studies, notably in vaccine efficacy assessment. Lumpfish (Cyclopterus lumpus) has become a valuable model for marine pathogenesis studies. This study evaluated several antigen preparations against A.

Transcriptome profiling of lumpfish (Cyclopterus lumpus) head kidney to Renibacterium salmoninarum at early and chronic infection stages.

Renibacterium salmoninarum causes Bacterial Kidney Disease (BKD) in several fish species. Atlantic lumpfish, a cleaner fish, is susceptible to R. salmoninarum.

Role of riboflavin biosynthesis gene duplication and transporter in virulence in marine teleost fish.

Active flavins derived from riboflavin (vitamin B) are essential for life. Bacteria biosynthesize riboflavin or scavenge it through uptake systems, and both mechanisms may be present. Because of riboflavin's critical importance, the redundancy of riboflavin biosynthetic pathway (RBP) genes might be present.

Multi-Organ Transcriptome Response of Lumpfish () to Subspecies Systemic Infection.

Lumpfish is utilized as a cleaner fish to biocontrol sealice infestations in Atlantic salmon farms. , a Gram-negative facultative intracellular pathogen, is the causative agent of furunculosis in several fish species, including lumpfish. In this study, lumpfish were intraperitoneally injected with different doses of to calculate the LD.

Nutritional immunomodulation of Atlantic salmon response to bacterin.

We investigated the immunomodulatory effect of varying levels of dietary ω6/ω3 fatty acids (FA) on Atlantic salmon () antibacterial response. Two groups were fed either high-18:3ω3 or high-18:2ω6 FA diets for 8 weeks, and a third group was fed for 4 weeks on the high-18:2ω6 diet followed by 4 weeks on the high-18:3ω3 diet and termed "switched-diet". Following the second 4 weeks of feeding (i.

Host-Pathogen Interactions of Marine Gram-Positive Bacteria.

Marine Gram-positive bacterial pathogens, including , , , , and spp. cause economic losses in marine fish aquaculture worldwide. Comprehensive information on these pathogens and their dynamic interactions with their respective fish-host systems are critical to developing effective prophylactic measures and treatments.

Comparative Reverse Vaccinology of , , , and , Frequent Pathogens of Atlantic Salmon and Lumpfish Aquaculture.

Marine finfish aquaculture is affected by diverse infectious diseases, and they commonly occur as co-infection. Some of the most frequent and prevalent Gram-negative bacterial pathogens of the finfish aquaculture include , , , and . To prevent co-infections in aquaculture, polyvalent or universal vaccines would be ideal.

Comparative Genomics of Typical and Atypical Complete Genomes Revealed New Insights into Pathogenesis Evolution.

is a global distributed Gram-negative teleost pathogen, affecting mainly salmonids in fresh and marine environments. strains are classified as typical or atypical depending on their origin of isolation and phenotype. Five subspecies have been described, where   subsp.

Lumpfish () Is Susceptible to Infection and Induces Cell-Mediated Immunity in the Chronic Stage.

is a Gram-positive, intracellular pathogen that causes Bacterial Kidney Disease (BKD) in several fish species in freshwater and seawater. Lumpfish () is utilized as a cleaner fish to biocontrol sea lice infestation in Atlantic salmon () farms. Atlantic salmon is susceptible to , and it can transfer the infection to other fish species.

Oral Immunization of Larvae and Juvenile of Lumpfish () against Does Not Influence Systemic Immunity.

, a marine bacterial pathogen that causes vibriosis, is a recurrent pathogen of lumpfish Lumpfish is utilized as a cleaner fish in the Atlantic salmon () aquaculture in the North Atlantic region because of its ability to visualize and prey on the ectoparasite sea lice () on the skin of Atlantic salmon, and its performance in cold environments. Lumpfish immunity is critical for optimal performance and sea lice removal. Oral vaccine delivery at a young age is the desired method for fish immunization because is easy to use, reduces fish stress during immunization, and can be applied on a large scale while the fish are at a young age.

A Novel Marine Pathogen Isolated from Wild Cunners (): Comparative Genomics and Transcriptome Profiling of sp. Strain J380.

Cunner () is a cleaner fish being considered for utilized in the North Atlantic salmon () aquaculture industry to biocontrol sea lice infestations. However, bacterial diseases due to natural infections in wild cunners have yet to be described. This study reports the isolation of sp.

Comparative Genomics Analysis of Isolated from Lumpfish () in Newfoundland Reveal Novel Chromosomal Organizations.

is a Gram-negative marine pathogen causative agent of vibriosis in a wide range of hosts, including invertebrates and teleosts. Lumpfish (), a native fish of the North Atlantic Ocean, is utilized as cleaner fish to control sea lice () infestations in the Atlantic salmon () aquaculture industry. is one of the most frequent bacterial pathogens affecting lumpfish.

Aeromonas salmonicida infection kinetics and protective immune response to vaccination in sablefish (Anoplopoma fimbria).

Effective vaccine programs against Aeromonas salmonicida have been identified as a high priority area for the sablefish (Anoplopoma fimbria) aquaculture. In this study, we established an A. salmonicida infection model in sablefish to evaluate the efficacy of commercial vaccines and an autogenous vaccine preparation.

Profiling the transcriptome response of Atlantic salmon head kidney to formalin-killed Renibacterium salmoninarum.

Renibacterium salmoninarum is a Gram-positive, intracellular bacterial pathogen that causes Bacterial Kidney Disease (BKD) in Atlantic salmon (Salmo salar). The host transcriptomic response to this immune-suppressive pathogen remains poorly understood. To identify R.

Identification and validation of reliable Aeromonas salmonicida subspecies salmonicida reference genes for differential gene expression analyses.

Aeromonas salmonicida subsp. salmonicida is a Gram-negative, facultative intracellular pathogen of a wide range of freshwater and marine fish species. A.

Vibrogen-2 vaccine trial in lumpfish (Cyclopterus lumpus) against Vibrio anguillarum.

Lumpfish (Cyclopterus lumpus), a native fish of the North Atlantic Ocean, is utilized as cleaner fish to biocontrol sea lice infestations in Atlantic salmon aquaculture. However, bacterial infections are affecting cleaner fish performance. Vibrio anguillarum, the aetiological agent of vibriosis, is one of the most frequent bacterial infections in lumpfish, and effective vaccine programmes against this pathogen have been identified as a high priority for lumpfish.