Comparisons of postoperative outcomes of laparoscopic versus open surgery using inverse probability of treatment weighting analysis: an evidence from Iran.

Background: Colorectal cancer has created a significant burden worldwide, including in Iran. Open and laparoscopic surgery are important treatment methods for this disease. The aim of this study is to compare postoperative outcomes of laparoscopic versus open surgery in Iran, with a particular emphasis on controlling confounding factors.

The anti-inflammatory effects of antidepressants on colitis.

Aim: Clomipramine (tricyclic antidepressant), Risperidone (a non-typical antidepressant), and Escitalopram (selective serotonin reuptake inhibitor antidepressant) might be good candidates for investigating the anti-colitis activity.

Background: The incidence of depression with ulcerative colitis in patients has led to the use of antidepressants in their treatment. In addition to the antidepressant effect of these drugs, anti-inflammatory effects have also been reported.

Adiponectin and leptin levels of patients after sleeve gastrectomy, Roux-en-Y gastric bypass, and single anastomosis sleeve ileal bypass surgeries.

Background: Bariatric surgery is an appropriate treatment for obese patients with metabolic syndrome. Adipose tissue is an active endocrine tissue secreting leptin and adiponectin that affect body metabolism. Nowadays, a high incidence of metabolic syndrome with an increased risk of serious diseases has been detected in Shiraz.

The effectiveness of an online video-based group schema therapy in improvement of the cognitive emotion regulation strategies in women who have undergone bariatric surgery.

Background: Adaptive cognitive emotion regulation (CER) strategies toward eating play a very important role in obesity and according to schema therapy, patients with obesity learn that don't respond to their emotional stimuli by eating. Thus, this study aimed to evaluate the effectiveness of an online video-based group schema therapy in improvement of the CER strategies and body mass index (BMI) in women who had undergone bariatric surgery.

Methods: Forty women who had undergone sleeve gastrectomy were selected and randomly divided into two groups of control and experimental.

Evaluation of Inflammatory Cytokine and Anti Antibodies in the Pathogenesis of Parkinson's Disease.

: Parkinson's disease is a neurodegenerative disorder characterized by degeneration of dopaminergic neurons in the substantia nigari. Previous studies have shown that infection is associated with treatment and clinical response to Parkinson's disease. In the present study, we aimed to investigate the effect of infection in the pathogenesis of Parkinson's disease.

Bone Densitometry and Fat Index after Sleeve and Subsleeve Gastrectomy in Animal Model.

Background: Previous studies have reported that gastrectomy and fundectomy can induce osteopenia. Body fat index is a new index of obesity that shows central obesity and other risks of obesity. Sleeve gastrectomy (SG) is a bariatric surgery and a new technique introduced as subsleeve, which only resected fundus of the stomach.

Mortality-Related Risk Factors for Coronavirus Disease (COVID-19)-Associated Mucormycosis: a systematic review and meta-analysis.

Purpose Of Review: Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) can increase the susceptibility of individuals to contracting mucormycosis through several mechanisms. Nowadays, coronavirus disease (COVID-19)-associated mucormycosis (CAM) is a serious public health concern, particularly in developing countries. This meta-analysis aims to identify the risk factors that affect the mortality rate of patients with CAM.

larval therapy in the treatment of diabetic chronic wounds.

Purpose: Wounds with dead tissue, purulent wounds, and gangrene are good options for larval therapy. We aim to investigate the effect of larval therapy on diabetic wounds and compare it with traditional treatment.

Methods: The sterile larvae were used in wound treatment and the infection rate, Erythrocyte Sedimentation Rate (ESR), and wound size were measured and compared before and after the treatment.

Evaluation of the efficacy of Zataria multiflora essential oil versus albendazole in patients infected with liver cystic echinococcosis: A nonrandomized clinical trial.

Background: Cystic echinococcosis (CE) is a life-threatening disease in many countries. Albendazole, as the drug of choice for medical treatment of CE, is accompanied by adverse effects and may be ineffective in 20%-40% of cases; hence, new and more effective compounds are urgently needed to optimize the management of the disease. This study was performed to evaluate the efficacy of essential oil (ZMEO) versus albendazole against human liver CE.

The Short-Term Effects of Oil and Sesame Oil on Liver and Kidney Pathology of Rats and Human Cancer Cell Lines.

Background: Vegetable oils recently have been evaluated in many tissues. (mastic) of the Anacardiaceae family and (sesame) of the Pedaliaceae family are conventionally used in the management of gastrointestinal, lung, and skin illnesses. This assay attempts to determine if the oral usage of mastic and sesame oils has any short-term toxic effects on the rat and evaluate the human anticancer effect .

Mechanical effects of ranolazine on normal and diabetic-isolated rat heart.

Background And Purpose: Diabetic cardiomyopathy is a complication of diabetes defined as cardiac dysfunction without the involvement of pericardial vessels, hypertension, or cardiac valve disorders. Ranolazine, an antianginal drug, acts through blocking of cardiac late sodium channels and/or inhibiting beta-oxidation of fatty acids. With regard to its mechanism of action, the present work has been carried out to investigate the potential useful effects of ranolazine on the systolic and diastolic dysfunctions in an experimental rat model of diabetic cardiomyopathy.

In Vitro Cytotoxicity and Apoptotic Assay of Eucalyptus globulus Essential Oil in Colon and Liver Cancer Cell Lines.

Purpose: Toxic effects of vegetables have been the subject of numerous investigations in recent years. Eucalyptus globulus of the Myrtaceae family has been traditionally used in the treatment of various infectious disorders. This study aims to assay the potential anticancer effect of Eucalyptus globulus essential oil, in vitro, and compare its cytotoxic effects on cancerous and non-cancerous cell lines.

Self-management Behaviors and Anthropometric Indices after Roux-en-Y Gastric Bypass.

Background: The aim of this study was to correlate the connection between self-management behaviors and anthropometric indices after Roux-en-Y gastric bypass (RYGB).

Methods: A sample of 180 patients suffering from obesity were treated with RYGB in 2019; 6 and 18 months after surgery, anthropometric indices, including weight, waist circumference, waist- to-height ratio, body mass index (BMI), and waist-to-hip ratio, were gauged, and participants completed the post-bariatric surgery self-management behaviors questionnaire.

Results: Correlation matrix results showed that all anthropometric indices had a significant positive relationship with self-management behaviors after RYGB; the results of the 18-month post-surgical follow-up exhibited no significant difference between anthropometric indices and self-management behaviors, 6 and 18 months after surgery.

Self-Efficacy, Happiness and Psychological Well-Being After Sleeve Gastrectomy.

Purpose: Sleeve gastrectomy (SG) is an effective treatment for patients with severe obesity and it leads to significant weight loss and promotes the quality of life. The aim of this study was evaluating the relationship between self-efficacy, happiness and psychological well-being after sleeve gastrectomy.

Methods: One hundred patients that underwent SG were participated in this study.

The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis.

Introduction: The mastic tree (Pistacia lentiscus), belonging to the Anacardiaceae family, has anti-inflammatory and antioxidant properties. This study aims to assay the anti-inflammatory effects of mastic in rats with colitis.

Methods: Forty-eight male Sprague-Dawley rats were randomly divided into six groups of control, colitis without treatment, colitis with mastic (400 mg/kg/daily) administered orally or intra-rectally, colitis with prednisolone (5 mg/kg of body weight), and colitis with sesame oil for seven successive days.

Electrocardiological effects of ranolazine and lidocaine on normal and diabetic rat atrium.

Purpose: Cellular changes occurring in diabetic cardiomyopathy include disturbances of calcium and sodium homeostasis. Voltage-gated sodium channels are responsible for the initiation of cardiac action potentials, and the excitability would create relevance. The effect of ranolazine as a sodium channel blocker on atrium electromechanical parameters is investigated and compared with lidocaine in streptozocin-treated diabetic rats.

Evaluation the Effects of Essential Oil and Hypertonic Saline as Scolicidal Agents in Induction of Sclerosing Cholangitis in Rabbits.

Background: There are several scolicidal agents for inactivation of hydatid cyst protoscolices during surgery, but most of them are associated with adverse side effects such as sclerosing cholangitis (SC) and liver necrosis. The present study aimed to evaluate the adverse effects of essential oil to induce SC in animal models.

Materials And Methods: Eighteen rabbits weighting 2000-3500 g were included in three groups for this study.

Do clinicopathologic features of rectal and colon cancer guide us towards distinct malignancies?

Background: Unlike developed countries where studies on all aspects of colorectal cancers are widely numerous, Iran as a Middle Eastern country show very few studies especially ones comparing the differences between colon and rectal cancer. In this study, firstly we report demographic, clinical and pathologic characteristics of patients with rectum and colon cancer and secondly compare these findings in order to investigate probable differences.

Methods: In this cross-sectional study, 238 patients were divided into two groups: the rectal cancer group and the colonic cancer group.

Outcomes of Implementation of Sacral Nerve Stimulation in Incontinent Patients in Shiraz.

Background: Fecal incontinence is a common disorder in old age; however, it may not threaten life, but it can cause morbidity and many problems. Sacral nerve stimulation (SNS) is a minimally invasive surgical procedure performed by chronic electrical stimulation of the nerves in the sacral plexus through a lead implanted at the S3 foramen. This study aimed to evaluate the outcomes of SNS in Shiraz.

Effects of Stapled Hemorrhoidopexy on Anorectal Function: A Prospective Randomized Controlled Trial.

Background: Stapled hemorrhoidopexy is a safe and acceptable alternative to traditional hemorrhoidectomy with shorter hospital stay, better satisfaction, and less postoperative pain. There have, however, been reports on early and late complications. Therefore, the present study was designed to assess the impact of stapled hemorrhoidopexy on anorectal function and continence.

Human Amniotic Membrane Effect on Perianal Fistula Healing in Rabbits: An Experimental Study.

Background: Perianal fistula is a complicated disorder and most difficult to manage. New treatment methods would help surgeons to achieve a better outcome in patients with perianal fistula. Human amniotic membrane (HAM) has positive effects on wound healing in several conditions.

Relationship between Body Image and Psychological Well-being in Patients with Morbid Obesity.

Background: Morbid obesity is rising around the world. It can cause unpleasant appearance and body image. Most of the studies have aimed to evaluate the psychopathology of overweight and obesity and paying attention to mental well-being in morbid obese individuals is rare.

Early Outcome of Patient with Ulcerative Colitis who Received High Dose of Steroid and Underwent Two Staged Total Proctocolectomy.

Background: Ulcerative colitis (UC) is an idiopathic inflammatory disorder. Currently, the final treatment is colectomy. The aim of this study was to investigate the outcomes of proctocolectomy in patients that used a high dose of prednisolone.