Publications by authors named "Haizhou Yu"

Gold (Au) nanoclustersare promising photocatalysts for biomedicine, sensing, and environmental remediation. However, the short carrier lifetime, inherent instability, and unclear charge transfer mechanism hinder their application. Herein, the Au nanoclusters decorated with three different isomers of o-Aminophenol, m-Aminophenol, and p-Aminophenol are synthesized, namely o-Au, m-Au, and p-Au, which achieve efficient hydrogen peroxide (HO) photoproduction through two-step one-electron oxygen reduction reaction (ORR).

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Article Synopsis
  • Dual-emission light-emitting diodes (DEDs) show potential for applications in fields like medical imaging and optical communication, but material design and packaging are ongoing challenges.
  • A novel method was developed using commercially available materials, specifically a mix of carbon dots (CDs) and a luminescent polymer, to create DEDs that emit at two wavelengths (436 nm and 632 nm).
  • The CDs enhance performance by storing and reinjecting charges into the polymer, improving long-wavelength emission, offering a fresh approach to designing effective DEDs.
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  • Gastric cancer (GC) has a poor prognosis and is characterized by aggressive development, prompting research into circular RNAs (circRNAs) as potential biomarkers and therapeutic targets, specifically hsa_circ_0008667.
  • This study analyzed the expression of hsa_circ_0008667 in GC tissues and cells, finding it linked to lymph node metastasis and a higher tumor-node-metastasis stage, indicating a worse patient prognosis.
  • The silencing of hsa_circ_0008667 suppressed GC cell growth and invasion, while also negatively regulating miR-9-5p, suggesting that hsa_circ_0008667 could serve as a valuable prognostic biomarker and tumor promoter in GC.
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Bisdemethoxycurcumin (BDMC) is one of major forms of curcuminoids found in the rhizomes of turmeric. Docetaxel (DTX) is the standard of care for men diagnosed with androgen-independent prostate cancers. Here we report for the first time that BDMC could reinforce the effect of DTX against prostate cancer in vitro and in vivo.

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Gastric cancer, a prevalent malady within the digestive tract, has a complex pathological mechanism and numerous patients. The regulation of gastric cancer process by long non-coding RNA (lncRNA) presented new prospects for the study of its molecular mechanism and the treatment of patients. The abnormal expressed genes in gastric cancer were screened by GSE193109 dataset.

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Aqueous zinc-ion batteries (AZIBs) are considered as attractive energy storage systems with great promise owing to their low cost, environmental friendliness and high safety. Nevertheless, cathode materials with stable structure and rapid diffusion of zinc ions are in great demand for AZIBs. In this work, a new kind of potassium vanadate compound (KV O ) is synthesized with fibrous morphology as an excellent cathode material for AZIBs, which shows outstanding electrochemical performance.

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Seeking cathode materials with high areal capacity and excellent cycling tolerance is a key step to develop aqueous rechargeable zinc-based alkaline batteries with high energy density, power density and excellent stability. Here, the bilayered cathode composite (MCN-LDH@CP) of molybdate intercalated cobalt-nickel layered hydroxide nanosheets (MCN-LDH) grown on cobalt phosphate octahydrate microsheet (CP) was prepared by a two-step hydrothermal process. Molybdate intercalation significantly reduces the thickness of cobalt-nickel layered hydroxide, greatly increases its specific surface area, regulates its pore distribution, increases the crystal plane spacing, promotes the diffusion rate of hydroxide in it, and increases its specific capacity.

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Lithium-sulfur batteries (LSBs) have attracted much attention due to their high energy density and theoretical specific capacity. However, the "shuttle effect" of polysulfides limits their application. Herein, we propose a postsynthetic modification (PSM) strategy to synthesize a fibrous carborane-tailored covalent organic framework (PMCB-COF).

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Herein, we described the self-assembly of a triblock copolymer, poly(styrene--2-vinylpyridine--ethylene oxide) (PS--P2VP--PEO), in THF/water at room temperature to form segmented wormlike nanostructures. We found two different formation mechanisms of the segmented wormlike nanostructures from PS--P2VP--PEO with different molecular weights. Moreover, the dimension of such segmented wormlike nanostructures depends on the stirring rate.

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The purpose of this research was to explore the diagnostic/prognostic significance and prospective molecular mechanisms of mitogen-activated protein kinase kinase kinases () in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Diagnostic/prognostic significance of was screened in the GSE1450 data set and validated in the Guangxi cohort. Various bioinformatics tools were used to explore the biological functions of prognosis-related genes.

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Lithium-sulfur batteries (LSBs) have been considered as one of the most promising energy storage systems because of their high theoretical energy density. However, the "shuttle effect" caused by polysulfide results in poor cycling stability and low electrochemical properties, which strongly impedes the practical application of LSBs. Herein, a kind of amphiphilic carborane-based covalent organic framework (CB-COF) is synthesized and treated as nano-trappers for polysulfide.

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The ectopic expression of ubiquitin-specific peptidase 21 (USP21) is common in different types of cancer. However, its relationship with radio-sensitivity in cervical cancer (CC) remains unclear. In this study, we aimed to uncover the effect of USP21 on CC radio-resistance and its underlying mechanism.

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Background: Bladder cancer (BLCA) refers to the malignancy growth that spreads from the bladder linings to the bladder muscles. However, the impact of miR-22-3p and lncRNA TRPM2-AS on this tumor has generated divergent views in the literature. This research aimed to study the effects of lncRNA TRPM2-AS on BLCA and its interaction with miR-22-3p and GINS2 mRNA.

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An amphiphilic dimeric-podophyllotoxin (PODO) phospholipid was synthesized to assemble into liposomes as a combination of prodrug and nanocarrier. The results have demonstrated that the cell membrane-like delivery system possessed an improved cellular uptake and favorable antitumor efficacy with reduced side-effects. This strategy provides a new effective platform in drug delivery for cancer chemotherapy.

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Viral capsid-like materials have been recognized as bionanotechnology platforms with great potential in controlled drug release, gene transfer and bioimaging. However, their functions still need to be optimized in aspects such as efficient drug transfer and selective targeting. Herein, we report a simple alternative strategy to fabricate viral capsid-like titania (VCL-TiO2) bearing ordered mesoporous channels and protrusions on its surface.

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This study investigated the effect of muscle-derived stem cells (MDSCs) and adipose tissue-derived stem cells (ADSCs) in the treatment of stress urinary incontinence (SUI) and their differences in a rat model. MDSCs and ADSC were isolated from rats (n = 10), examined for their properties, and labeled with enhanced green fluorescent protein (EGFP) and β-galactosidase (β-gal) gene. Rats received bladder-neck and transurethral sphincter injection of EGFP-labeled MDSCs and β-gal gene-labeled ADSC and injection of D-Hanks as a control (n = 24 each group).

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This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).

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This study aimed to investigate the exact regulatory mechanisms of retinoid-interferon-induced mortality 19 (GRIM-19) in renal carcinoma. Tumour tissue samples from patients with renal carcinoma (n = 30, there were seven cases of Stage I, eight cases of Stage II, eight cases of Stage III, seven cases of Stage IV) and control subjects were selected from adjacent normal tissue (n = 10). Real-time quantitative PCR and western blotting were used to assess the level of GRIM-19, signal transducer and activator of transcription-3 (STAT3) and its downstream molecules.

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A phytochemical investigation of Ajuga forrestii Diels led to the isolation of 14 compounds, including eight neo-clerodane diterpenes (1-8), two phytoecdysteroids (9, 11), one stigmastane sterol (10) and three iridoid glycosides (12-14). The structures of these compounds were identified by spectroscopic methods and a comparison of their data with those reported in the literature. This is the first report of compounds 1-14 from A.

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To date, it is still a challenge to prepare high-flux and highselectivity microporous membranes thinner than 20 nm without introducing defects. In this work, we report for the first time the application of cellulose membranes for selective separation of small molecules. A freestanding cellulose membrane as thin as 10 nm has been prepared through regeneration of trimethylsilyl cellulose (TMSC).

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MiR-211 has strong inhibitive effects on melanoma cell growth, invasion and metastasis. However, how it is downregulated and whether other genes are involved its downstream regulation in melanoma are not clear. In this study, we firstly verified the expression of miR-211 in melanoma cell lines and observed that its downregulation is associated with increased DNMT1 expression.

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Recently two quite different types of "nano-containers" have been recognized as attractive potential drug carriers; these are wormlike filamenteous micelles ("filomicelles") on the one hand and metal organic frameworks on the other hand. In this work we combine these two concepts. We report for the first time the manufacturing of metal organic framework nanotubes with a hollow core.

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The self-assembly of block copolymers is an emerging strategy to produce isoporous ultrafiltration membranes. However, thus far, it has not been possible to bridge the gap from ultra- to nanofiltration and decrease the pore size of self-assembled block copolymer membranes to below 5 nm without post-treatment. It is now reported that the self-assembly of blends of two chemically interacting copolymers can lead to highly porous membranes with pore diameters as small as 1.

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The combination of nonsolvent-induced phase separation and the self-assembly of block copolymers can lead to asymmetric membranes with a thin highly ordered isoporous skin layer. The effective pore size of such membranes is usually larger than 15 nm. We reduced the pore size of these membranes by electroless gold deposition.

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