Discriminative Cervical Lesion Detection in Colposcopic Images With Global Class Activation and Local Bin Excitation.

Accurate cervical lesion detection (CLD) methods using colposcopic images are highly demanded in computer-aided diagnosis (CAD) for automatic diagnosis of High-grade Squamous Intraepithelial Lesions (HSIL). However, compared to natural scene images, the specific characteristics of colposcopic images, such as low contrast, visual similarity, and ambiguous lesion boundaries, pose difficulties to accurately locating HSIL regions and also significantly impede the performance improvement of existing CLD approaches. To tackle these difficulties and better capture cervical lesions, we develop novel feature enhancing mechanisms from both global and local perspectives, and propose a new discriminative CLD framework, called CervixNet, with a Global Class Activation (GCA) module and a Local Bin Excitation (LBE) module.

Leisure-time physical activity and milk intake synergistically reduce the risk of pathoglycemia: A cross-sectional study in adults in Beijing, China.

Background And Objectives: To evaluate the synergistic and individual associations of leisure-time physical activity (LTPA) intensity and the frequency of milk intake in adulthood with newly diagnosed pathoglycemia. Pathoglycemia comprised impaired fasting glucose (IFG) and type 2 diabetes mellitus (T2DM).

Methods And Study Design: This cross-sectional study of 3977 adults was conducted in Mentougou District, Beijing, China.

Study on the correlation between hTREC and HPV load and cervical CINI/II/III lesions and cervical cancer.

Objective: To investigate the correlation between hTREC and human papillomavirus (HPV) load and cervical intraepithelial neoplasia (CIN) grade II/III lesions and cervical cancer.

Methods: A total of 135 patients with cervical lesions of different degrees admitted to our hospital from January 2016 to February 2017 were selected, including CIN I/III 65 cases, grade III 39 cases, and cervical cancer 31 cases. The expression of hTERC gene was detected by fluorescence in situ hybridization (FISH) in three groups, and the HPV load was detected by second-generation hybridization capture (HC II) method, and its relationship with cervical lesion grade was analyzed.

Associations of physical activity and egg intake with hypertension among Chinese middle-aged and older population.

To explore the independent and interaction associations of physical activity (PA) and egg intake with hypertension. A cross-sectional study of 2189 individuals (aged ≥50 years) selected using multi-stage stratified random sampling was conducted in Mentougou of Beijing, China. Data of PA and egg intake were obtained from questionnaire survey, and blood pressure from physical examination.

Soy product consumption and type 2 diabetes among adults in Beijing, China.

Background And Objectives: To examine the association between the frequency of soy products consumption and type 2 diabetes or impaired fasting glucose.

Methods And Study Design: A cross-sectional study of 3,314 subjects aged 18-79 years was conducted in Beijing, China in 2016. Consumption of soy products was assessed by a validated food-frequency questionnaire and examined with type 2 diabetes or impaired fasting glucose risk using multiple logistic regression.

Colorimetric Detection of 23 Human Papillomavirus Genotypes by Loop-Mediated Isothermal Amplification.

Background: Human papillomavirus (HPV) infection is linked to cervical cancer. With the technological development of molecular biology and epidemiology, detection and treatment of HPV has become an important mean to prevent cervical cancer.

Methods: A simple, rapid, and sensitive colorimetric loop-mediated isothermal amplification (LAMP) method was established herein to detect 23 HPV genotypes.

Isothermal Method of a Recombinase Polymerase Amplification Assay for the Detection of Most Common High-Risk Human Papillomavirus Type 16 and Type 18 DNA.

Background: Cervical cancer is a common gynecologic malignant tumor and has a great impact on women's health. Human papillomavirus (HPV) is implicated in cervical cancer and precancerous lesions and the two are possibly two stages of disease progression. With the technological development of molecular biology and epidemiology, detection and treatment of HPV has become an important means to prevent cervical cancer.